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Classical and Alternative Pathways of Mast Cell Activation
Critical Reviews™ in Immunology, 2002It has long since been recognized that mast cells are critical effectors of anaphylactic reactions, and the existence of these potentially hazardous cells has solely been justified due to their beneficial role in some infections with extracellular parasites. A novel understanding of mast cells as sentinels of the immune system has been made possible by
Lothar Hültner +2 more
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An immunofluorescence assay for complement activation by the classical pathway
Journal of Immunological Methods, 1981The functional integrity of classical complement pathway components was determined by an immunofluorescence (IFL) assay based on the capacity of cytoskeletal intermediate filaments (IMF) to bind C1q and to activate the complement pathway. The assay uses IMF-rich capillary endothelium of human term placentae as complement-activating substrate.
S. Meri, M. Rhen, Ewert Linder
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The Initiation Complexes of the Classical and Lectin Pathways
2006Various antigen structures initiate the classical and the lectin pathways of complement activation. Multidomain modular proteases (C1r, C1s and MASPs) are involved in the initiation complexes of both pathways. Despite the identical domain organization of these serine proteases there are differences in their specificities and functions.
Géza Ambrus +3 more
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Classical pathway deficiencies – A short analytical review
Molecular Immunology, 2015Deficiencies in the classical pathway of complement activation have some common features but show also great differences. Deficiencies of each of the components (C1q, C1s, C1r, C4 and C2) imply increased susceptibility to bacterial infections. They are also associated with increased risk to develop systemic lupus erythematosus where deficiency of C1q ...
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CLASSICAL COMPLEMENT PATHWAY IN HIV INFECTION
The Lancet, 1989E T Davies +5 more
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In Situ Observation of Non‐Classical 2‐Norbornyl Cation in Confined Zeolites at Ambient Temperature
Angewandte Chemie - International Edition, 2021Wei Chen, Anmin Zheng, Zhiqiang Liu
exaly
Classical and alternative pathway of complement in amphibia
Developmental & Comparative Immunology, 1983B. Hofmanová +3 more
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