Results 41 to 50 of about 11,895 (212)

Determinants of Virulence of Classical Swine Fever Virus Strain Brescia [PDF]

Journal of Virology, 2004
ABSTRACT Two related classical swine fever virus (CSFV) strain Brescia clones were isolated from blood samples from an infected pig. Virus C1.1.1 is a cell-adapted avirulent variant, whereas CoBrB is a virulent variant. Sequence analysis revealed 29 nucleic acid mutations in C1.1.1, resulting in 9 amino acid substitutions ...
van Gennip, H.G.P., Vlot, A.C., Hulst, M.M., de Smit, A.J., Moormann, R.J.M.   +4 more
openaire   +2 more sources

Rate of inter-herd transmission of classical swine fever virus by different types of contact during the 1997-8 epidemic in The Netherlands

, 2002
In this study we quanti®ed the rate at which classical swine fever had been transmitted by several different types of inter-herd contact during the 1997±8 epidemic in The Netherlands. During that epidemic 428 CSFV-infected pig herds were detected, 403 of
Stegeman, J.A., Bouma, A., Jong, M.C.M., de, Elbers, A.R.W.   +3 more
core   +1 more source

Spatio-temporal epidemic modelling using additive-multiplicative intensity models [PDF]

, 2008
An extension of the stochastic susceptible-infectious-recovered (SIR) model is proposed in order to accommodate a regression context for modelling infectious disease surveillance data. The proposal is based on a multivariate counting process specified by
Höhle, Michael
core   +1 more source

Local spread of classical swine fever upon virus introduction into The Netherlands: Mapping of areas at high risk

, 2008
Background In the recent past, the introduction of Classical Swine Fever Virus (CSFV) followed by between-herd spread has given rise to a number of large epidemics in The Netherlands and Belgium.
Boender, G.J., Hagenaars, T.H.J., Jong, M.C.M., de, Nodelijk, G., Elbers, A.R.W.   +4 more
core   +1 more source

Assessing the Protective Dose of a Candidate DIVA Vaccine against Classical Swine Fever

Vaccines, 2021
Classical swine fever is a highly contagious and deadly disease in swine. The disease can be controlled effectively by vaccination with an attenuated virus known as the “Chinese” (C)-strain.
Tinka Jelsma, Jacob Post, Erwin van den Born, Ruud Segers, Jeroen Kortekaas   +4 more
doaj   +1 more source

Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)

Advanced Science, EarlyView.
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang, Jiahao Ding, Si Chen, Lijie Yan, Shichao Ding, Lavonda Li, Junyi Sun, Haodong Liu, Tongge Li, Ning Liu, Mingji Wei, Xiaoyong Zhu, Xiaobo Zou, Shouqi Yuan, Xingcai Zhang   +14 more
wiley   +1 more source

Interaction of classical swine fever virus with dendritic cells

Journal of General Virology, 2004
Functional disruption of dendritic cells (DCs) is an important strategy for viral pathogens to evade host defences. Monocytotropic viruses such as classical swine fever virus (CSFV) could employ such a mechanism, since the virus can suppress immune responses and induce apoptosis without infecting lymphocytes.
Carrasco, C.P., Rigden, R.C., Vincent, I.E., Balmelli, C., Ceppi, M., Bauhofer, O., Tache, V., Hjertner, B., McNeilly, F., van Gennip, H.G.P., McCullough, K.C., Summerfield, A.   +11 more
openaire   +2 more sources

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source