Results 191 to 200 of about 135,129 (369)

Evaluating the potential of RNA interference for control of striped cucumber beetle, Acalymma vittatum (Fabricius) (Coleoptera: Chrysomelidae)

open access: yesPest Management Science, EarlyView.
SCB has a robust RNAi response to injected dsRNA, but oral RNAi is less efficient. Nucleases do not appear to be responsible for the discrepancy, suggesting other factors are involved. Abstract BACKGROUND The striped cucumber beetle (SCB) is a serious pest of cucurbit crops, causing damage both by feeding on plants and by vectoring plant diseases ...
Emine Kaplanoglu   +2 more
wiley   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

open access: yesPest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus   +13 more
wiley   +1 more source

Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2 [PDF]

open access: gold, 2016
Luis L. P. daSilva   +6 more
openalex   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

open access: yesSmall, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi   +13 more
wiley   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

open access: yesSmall, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom   +6 more
wiley   +1 more source

Endocytosis of Ubiquitylation‐Deficient EGFR Mutants via Clathrin‐Coated Pits is Mediated by Ubiquitylation [PDF]

open access: bronze, 2015
Arola Fortian   +6 more
openalex   +1 more source

Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders

open access: yesSmall, EarlyView.
Little is known about the effects of polystyrene nanoplastics (PS‐NPs) on gonadotropin releasing hormone (GnRH) neurons, which control puberty onset and fertility. By applying tailored in vitro GnRH neuron models, this article shows how PS‐NPs are internalized and impact hormone secretion and cell migration, through gene expression changes. Ultimately,
Federica Amoruso   +14 more
wiley   +1 more source

Clathrin is required for Scar/Wave-mediated lamellipodium formation [PDF]

open access: bronze, 2011
Jérémie Gautier   +11 more
openalex   +1 more source

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