Results 191 to 200 of about 126,267 (387)
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.SuperResNET is a powerful integrated software that reconstructs network architecture and molecular distribution of subcellular structures from single molecule localization microscopy datasets. SuperResNET segments the nuclear pore complex and corners, extracts size, shape, and network features of all segmented nuclear pores and uses modularity analysis
Yahongyang Lydia Li +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.The construction of mitochondria‐targeted nanomedicine is achieved by incorporating into COFs a prodrug, which is a catalase inhibitor and a Fenton‐like reaction copper complex linked by a disulfide bond. These findings confer organelle‐specific targeting properties to COF materials for efficient delivery of therapeutic drugs and enhanced cancer ...
Qihang Ding +9 more
wiley +2 more sources
AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear +16 more
wiley +1 more source
Angewandte Chemie, EarlyView.The proposed Bio‐Cy conjugate emerges as an avant‐garde molecular entity, adeptly activating the pyroptosis and cGAS‐STING pathways by disrupting pyroptosis checkpoints to heighten the cytocidal impact of photon‐driven immunotherapy. Abstract Immunotherapy is a groundbreaking approach for clinically treating tumors, but its effectiveness is hindered by
Shuang Zeng +15 more
wiley +2 more sources
An ATP-driven proton pump in clathrin-coated vesicles.
, 1983 Dennis K. Stone +2 more
openalex +1 more source
Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. [PDF]
, 1993 L H Wang +2 more
openalex +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Neuroaxonal dystrophy (NAD) with osteopetrosis syndrome (OMIM # 600329) was first reported in a consanguineous Moroccan Jewish family. However, to date, no genetic variant has been linked to this disease. We report on sibs, born to consanguineous Pakistani parents identified prenatally with cerebral ventriculomegaly and agenesis of the corpus ...
Yael Fisher +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Self‐assembled thiol‐rich polypseudorotaxanes with high modularity were developed via a “one‐pot” preparation through the threading of thiolated α‐cyclodextrins on polymers and subsequent oxidation of thiols into disulfide bonds. This dynamic motif was used as a functionalization platform for thiophilic metal nanoparticles, either tethering them to a ...
Xiang Xu +12 more
wiley +2 more sources
Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats.
, 1983 S Zaremba, James H. Keen
openalex +1 more source