Results 261 to 270 of about 135,129 (369)
Quantifying the dynamic interactions between a clathrin-coated pit and cargo molecules [PDF]
Aubrey V. Weigel +2 more
openalex +1 more source
Clathrin-mediated endocytosis in budding yeast at a glance
Rebecca Lu, D. Drubin, Yidi Sun
semanticscholar +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava +9 more
wiley +1 more source
GRK phosphorylation drives β-arrestin-independent internalization of chemokine receptor CXCR5. [PDF]
Crecelius JM +6 more
europepmc +1 more source
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley +1 more source
Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis. [PDF]
Maestro A +15 more
europepmc +1 more source
ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar +4 more
wiley +1 more source
Enhanced visualization of influenza A virus entry into living cells using virus-view atomic force microscopy. [PDF]
Yoshida A +5 more
europepmc +1 more source

