Results 61 to 70 of about 126,267 (387)
Synaptic vesicles are primed for fast clathrin-mediated endocytosis at the ribbon synapse
Frontiers in Molecular Neuroscience, 2014 Retrieval of synaptic vesicles can occur 1-10 s after fusion, but the role of clathrin during this process has been unclear because the classical mode of clathrin-mediated endocytosis (CME) is an order of magnitude slower, as during retrieval of surface ...
Ilaria ePelassa +8 more
doaj +1 more source
Clathrin heavy chain is important for viability, oviposition, embryogenesis and, possibly, systemic RNAi response in the predatory mite Metaseiulus occidentalis. [PDF]
PLoS ONE, 2014 Clathrin heavy chain has been shown to be important for viability, embryogenesis, and RNA interference (RNAi) in arthropods such as Drosophila melanogaster.
Ke Wu, Marjorie A Hoy
doaj +1 more source
Conformation Switching of Clathrin Light Chain Regulates Clathrin Lattice Assembly [PDF]
Developmental Cell, 2010 Clathrin-coated vesicle formation is responsible for membrane traffic to and from the endocytic pathway during receptor-mediated endocytosis and organelle biogenesis, influencing how cells relate to their environment. Generating these vesicles involves self-assembly of clathrin molecules into a latticed coat on membranes that recruits receptors and ...
Michael Lane +7 more
openaire +3 more sources
An ultrasensitive sorting mechanism for EGF receptor endocytosis [PDF]
, 2008 Background The EGF receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling ...
Dikic, Ivan +4 more
core +2 more sources
Nature Communications, 2018 Using real-time TIRF microscopy imaging, we identify sites of clathrin and dynamin-independent CLIC/GEEC (CG) endocytic vesicle formation. This allows spatio-temporal localisation of known molecules affecting CG endocytosis; GBF1 (a GEF for ARF1), ARF1 ...
Mugdha Sathe +7 more
semanticscholar +1 more source
Clathrin-independent pathways of endocytosis. [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 There are many pathways of endocytosis at the cell surface that apparently operate at the same time. With the advent of new molecular genetic and imaging tools, an understanding of the different ways by which a cell may endocytose cargo is increasing by leaps and bounds.
S. Mayor, R. Parton, J. Donaldson
semanticscholar +5 more sources
Molecular Cancer, 2013 Background During metaphase clathrin stabilises the mitotic spindle kinetochore(K)-fibres. Many anti-mitotic compounds target microtubule dynamics.
Smith Charlotte M +4 more
doaj +1 more source
Molecular Brain, 2020 Clathrin-mediated endocytosis plays an important role in the recycling of synaptic vesicle in presynaptic terminals, and in the recycling of transmitter receptors in neuronal soma/dendrites.
Jung-Hwa Tao-Cheng
doaj +1 more source
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling. [PDF]
PLoS ONE, 2011 Endocytosis of tyrosine kinase receptors can influence both the duration and the specificity of the signal emitted. We have investigated the mechanisms of internalization of fibroblast growth factor receptor 3 (FGFR3) and compared it to that of FGFR1 ...
Ellen Margrethe Haugsten +6 more
doaj +1 more source
Clathrin‐independent internalization and recycling [PDF]
Journal of Cellular and Molecular Medicine, 2007 Introduction Clathrin‐dependent internalization Clathrin‐independent internalization Macropinocytosis Caveolae‐dependent internalization Clathrin‐and‐caveolae‐independent internalization Pericentrion, a novel PKC‐dependent recycling endosomal structure Clathrin‐independent pathways in neuronal cells Summary AbstractThe functionality of receptor and ...
Dzwokai Ma +2 more
openaire +3 more sources