Results 81 to 90 of about 21,285,591 (295)
Antioxidants, 2022 Claudin 5 is one of the major proteins of tight junctions and is responsible for cerebrovascular integrity and BBB function. Muscone and (+)-borneol is the major ingredient of moschus and borneolum, respectively, with antioxidative and anti-inflammatory ...
Yu-Chen Li +8 more
doaj +1 more source
Development of Claudin 2 and Claudin 4 in Embryonic and Hatched Chick Intestine [PDF]
, 2008 The epithelium of the vertebrate intestine is a dynamic structure, under constant renewal. The intestinal crypts represent a proliferative compartment that is monoclonal and is maintained by multiple stem cells.
Wingate, Marvin Jason
core
Advanced Science, EarlyView.Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang +11 more
wiley +1 more source
Claudin 1 mediates TNFα-induced gene expression and cell migration in human lung carcinoma cells.
PLoS ONE, 2012 Epithelial-mesenchymal transition (EMT) is an important mechanism in carcinogenesis. To determine the mechanisms that are involved in the regulation of EMT, it is crucial to develop new biomarkers and therapeutic targets towards cancers.
Atsushi Shiozaki +8 more
doaj +1 more source
Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst
Cells, 2020 Embryo implantation into the uterine wall is a highly modulated, complex process. We previously demonstrated that Annexin A1 (AnxA1), which is a protein secreted by epithelial and inflammatory cells in the uterine microenvironment, controls embryo ...
Cristina B. Hebeda +7 more
doaj +1 more source
Romanian Journal of Laboratory Medicine, 2022 Background: Claudin-1 is involved in various cancers, but its expression and role in gastric carcinoma remain unclear.
Lv Jun, She Zhuocui, Cai Ang
doaj +1 more source
IL-17 decreases zona occludens 1 (ZO-1), claudin-1, and claudin-4 synthesis in a skin-equivalent model. [PDF]
, 2016 (a) Double-immunostaining of claudin-1 (fluorescein isothiocyanate; green) and claudin-4 (Cy3, red) was performed in skin-equivalent model specimens incubated with IL-17. Scale bars = 50 μm.
Takuo Yuki (3097797) +4 more
core +1 more source
Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, EarlyView.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells
International Journal of Medical Sciences, 2009 Cytoplasmic expression of claudin-1 in metastatic melanoma cells correlates to increased migration, and increased secretion of MMP-2 in a PKC dependent manner, whereas claudin-1 nuclear expression is found in benign nevi.
Amanda D. French, Jennifer L. Fiori, Tura C. Camilli, Poloko D. Leotlela, Michael P. O'Connell, Brittany P. Frank, Sarah Subaran, Fred. E. Indig, Dennis D. Taub, Ashani T. Weeraratna
doaj
Advanced Science, EarlyView.Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin +13 more
wiley +1 more source