Results 61 to 70 of about 21,285,591 (295)

Expression of claudin 1, 4 and 7 in thyroid neoplasms

Oncology Letters, 2017
The distinction of thyroid carcinoma from benign thyroid neoplasm, as well as the subtyping of papillary carcinoma (PC) and follicular carcinoma (FC), may be performed histopathologically in the majority of cases. However, in certain cases, it is difficult to histopathologically distinguish between PC and FC, as well as follicular adenoma (FA), FC and ...
Suren, Dinc, Yildirim, Mustafa, Sayiner, Alper, Alikanoglu, Arsenal Sezgin, Atalay, Irem, Gunduz, Seyda, Gunduz, Umutriza, KAYA, Vildan, ORUÇ, MEHMET SEBİH, Sezer, Cem   +9 more
openaire   +5 more sources

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Claudin-1 is a p63 target gene with a crucial role in epithelial development.

PLoS ONE, 2008
The epidermis of the skin is a self-renewing, stratified epithelium that functions as the interface between the human body and the outer environment, and acts as a barrier to water loss.
Teresa Lopardo, Nadia Lo Iacono, Barbara Marinari, Maria L Giustizieri, Daniel G Cyr, Giorgio Merlo, Francesca Crosti, Antonio Costanzo, Luisa Guerrini   +8 more
doaj   +1 more source

Representative photographs of colonic claudin-1, claudin-2 and claudin-3 immunostaining in mice. [PDF]

, 2013
Moderate claudin-1 immunostaining was observed in colons from control group (A). The intensity was significantly decreased in colitis group (B), and increased when treated with AMD3100 (C).
Xian-Ming Xia (340280), Bing-Bing Zou (340288), Ju Zhou (340283), Su-Wen Li (340287), Kai-Feng Hu (340284), Fang-Yu Wang (340282)   +5 more
core   +1 more source

Claudin 1 and nephrin label cellular crescents in diabetic glomerulosclerosis [PDF]

Human Pathology, 2014
Cellular crescents are typically inflammatory and associated with rapidly progressive glomerulonephritis. Their pathogenesis involves glomerular basement membrane rupture due to circulating or intrinsic factors. Crescents associated with diabetic glomerulosclerosis are rarely reported.
Joseph P, Gaut, Masato, Hoshi, Sanjay, Jain, Helen, Liapis   +3 more
openaire   +2 more sources

Lubiprostone Induces Claudin-1 and Protects Intestinal Barrier Function [PDF]

Pharmacology, 2019
<b><i>Introduction:</i></b> Lubiprostone, a chloride channel activator, is said to reduce epithelial permeability. However, whether lubiprostone has a direct effect on the epithelial barrier function and how it modulates the intestinal barrier function remain unknown.
Norio Nishii, Tadayuki Oshima, Min Li, Hirotsugu Eda, Kumiko Nakamura, Akio Tamura, Tomohiro Ogawa, Takahisa Yamasaki, Takashi Kondo, Tomoaki Kono, Katsuyuki Tozawa, Toshihiko Tomita, Hirokazu Fukui, Hiroto Miwa   +13 more
openaire   +2 more sources

The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]

, 2009
The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Nougayrède, Jean-Philippe, Oswald, Isabelle P, Moreno, Carolina, Marin, Daniela E., Loureiro-Bracarense, Ana-Paula, Ferrier, Laurent, Oswald, Isabelle P., Pinton, Philippe, Del Rio, Juan-Carlos, Kolf-Clauw, Martine, Bracarense, Ana-Paula   +10 more
core   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers [PDF]

, 2015
In epithelial/endothelial barriers, claudins form tight junctions, seal the paracellular cleft, and limit the uptake of solutes and drugs. The peptidomimetic C1C2 from the C-terminal half of claudin-1's first extracellular loop increases drug delivery ...
Staat, Christian, Andjelkovic, Anuska V, Dabrowski, Sebastian, Engelhardt, Britta, Coisne, Caroline Marie, Stamatovic, Svetlana M, Wolburg, Hartwig, Blasig, Ingolf E   +7 more
core   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source