Results 41 to 50 of about 21,285,591 (295)

Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells. [PDF]

PLoS ONE, 2012
Dysregulation of tight junctions (TJs) is often associated with human diseases including carcinogenesis and recent studies support role of TJ integral proteins in the regulation of Epithelial-to-Mesenchymal Transition (EMT). In this regard, expression of
Ajaz A Bhat, Ashok Sharma, Jillian Pope, Moorthy Krishnan, Mary K Washington, Amar B Singh, Punita Dhawan   +6 more
doaj   +1 more source

Claudin-2 and occludin protein expressions. [PDF]

, 2018
Western blot was used to measure claudin-2 (Fig 6A) and occludin (Fig 6B) protein expressions in intestine. The levels of claudin-2 and occludin in FF and BO groups were significantly decreased compared to the FO group. Claudin-2 and occludin levels were
David Clark (738), Qinghe Meng (3857866), Benjamin D. Sadowitz (5545631), Robert N. Cooney (748866), Shreyas K. Roy (5545622), Joshua Satalin (5545628), Michaela Kollisch-Singule (5545619), Louis A. Gatto (5545616), Natesh Yepuri (3857863), Gary F. Nieman (5545625)   +9 more
core   +1 more source

Claudin-Low Breast Cancer; Clinical & Pathological Characteristics. [PDF]

, 2017
Claudin-low breast cancer is a molecular type of breast cancer originally identified by gene expression profiling and reportedly associated with poor survival. Claudin-low tumors have been recognised to preferentially display a triple-negative phenotype,
John Hassell, Ying Wu, Mark Levine, Kay Dias, John Hassell (3529412), Gregory R. Pond (3611303), Gregory R Pond, Anita L Bane, Anita L. Bane (3611300), Robin M Hallett, Ying Wu (19057), Mark Levine (106449), Robin M. Hallett (328197), Anna Dvorkin-Gheva (201099), Tim Whelan (26979), Kay Dias (3529400), Anna Dvorkin-Gheva, Tim Whelan   +17 more
core   +1 more source

Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling. [PDF]

PLoS ONE, 2013
The altered expressions of claudin proteins have been reported during the tumorigenesis of colorectal cancer. However, the molecular mechanisms that regulate these events in this cancer type are poorly understood.
Waldemir F de Souza, Natalia Fortunato-Miranda, Bruno K Robbs, Wallace M de Araujo, Julio C de-Freitas-Junior, Lilian G Bastos, João P B Viola, José A Morgado-Díaz   +7 more
doaj   +1 more source

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm, Kathrin Hueging, Michael Ott, Hueging, Kathrin, Brohm, Christiane, Ott, Michael, Bitzegeio, Julia, Dorothea Bankwitz, Herrmann, Eva, Sibylle Haid, Thomas Pietschmann, Mirjam B. Zeisel, Baumert, Thomas F, Iken, Marcus, Haid, Sibylle, Marcus Iken, Julia Bitzegeio, Thomas F. Baumert, Zeisel, Mirjam B, Thomas F Baumert, Mirjam B Zeisel, Eva Herrmann, Baumert, Thomas, Bankwitz, Dorothea, Zeisel, Mirjam B., Pietschmann, Thomas   +25 more
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Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells

Cell Structure and Function, 2022
The claudin family of membrane proteins is responsible for the backbone structure and function of tight junctions (TJs), which regulate the paracellular permeability of epithelia.
Mikio Furuse, Daiki Nakatsu, Wendy Hempstock, Shiori Sugioka, Noriko Ishizuka, Kyoko Furuse, Taichi Sugawara, Yugo Fukazawa, Hisayoshi Hayashi   +8 more
doaj   +1 more source

Claudin-1 as a Biomarker of Cervical Cytology and Histology

Pathology & Oncology Research, 2015
Several immunochemistry tests are used for triaging human papilloma virus (HPV) and cytology positive cases in cervical cancer screening and as an adjunct test to diagnose cervical cancer. Claudin-1 (CLDN1) protein is a major component of the tight junction, shown to have altered expression in cervical cancer. In this study, value of CLDN1 was analysed
Márta, Benczik, Ádám, Galamb, Róbert, Koiss, Attila, Kovács, Balázs, Járay, Tamás, Székely, Tímea, Szekerczés, Zsuzsa, Schaff, Gábor, Sobel, Csaba, Jeney   +9 more
openaire   +3 more sources

Serum Zonula Occludens-1 and Claudin-5 Levels in Patients with Insomnia Disorder: A Pilot Study [PDF]

, 2023
Mei Fan, Fangyi Deng, Rui Tang, Yixian Cai, Xiaotao Zhang, Hongyao Li, Ting Xiang, Jiyang Pan Department of Psychiatry, Sleep Medicine Centre, The First Affiliated Hospital, Jinan University, Guangzhou, People’s Republic of ChinaCorrespondence: Jiyang ...
Li H, Pan J, Xiang T, Zhang X, Fan M, Tang R, Cai Y, Deng F   +7 more
core  

Low Claudin-1 Expression Has Association with Deep Invading and Higher-Grade Colorectal Adenocarcinoma

Indonesian Journal of Cancer, 2020
Background Claudin-1 is a tight junction protein in the cell that organizes paracellular permeability and epithelial polarity and maintains apical cell-to-cell adhesion.
Putu Erika Paskarani, Herman Saputra, Ni Putu Sriwidyani, I Gusti Ayu Sri Mahendra Dewi, Luh Putu Iin Indrayani Maker, I Made Muliartha   +5 more
doaj   +1 more source

A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients

Cells, 2021
Identifying molecular characteristics that are associated with aggressive cancer phenotypes through gene expression profiling can help predict treatment responses and clinical outcomes. Claudins are deregulated in colorectal cancer (CRC).
Saiprasad Gowrikumar, Mark Primeaux, Kristina Pravoverov, Chao Wu, Bryan C. Szeglin, Charles-Etienne Gabriel Sauvé, Ishwor Thapa, Dhundy Bastola, Xi Steven Chen, J. Joshua Smith, Amar B. Singh, Punita Dhawan   +11 more
doaj   +1 more source