Results 31 to 40 of about 21,285,591 (295)

Prognostic Role of Claudin-1 Immunohistochemistry in Malignant Solid Tumors: A Meta-Analysis [PDF]

Journal of Pathology and Translational Medicine, 2019
Background Although the correlation between low claudin-1 expression and worse prognosis has been reported, details on the prognostic implications of claudin-1 expression in various malignant tumors remain unclear.
Jung-Soo Pyo, Nae Yu Kim, Won Jin Cho
doaj   +1 more source

Claudin-1 localisation at the tight junctions is disrupted by PAF and restored by BML-111. [PDF]

, 2023
Composite X/Y confocal images of 16HBE14o- polarised monolayers untreated (control) or treated with P. aeruginosa filtrate (PAF) for 24h or PAF + 200 nmol/L BML-111 (BML) immunostained for (A) ZO-1 (red), (B) Claudin-1 (red), (C) E-cadherin (red). Nuclei
Sonya Jackson (3179151), Deborah L. Baines (11105430), Kameljit K. Kalsi (16496511)   +2 more
core   +1 more source

Regulation of Tight Junctions by Sex Hormones in Goat Mammary Epithelial Cells

Animals, 2022
The sex hormones of estrogen and progesterone (P4) play a vital role in mammary gland development and milk lactation in ruminants. The tight junction (TJ) between adjacent secretory epithelial cells is instrumental in establishing the mammary blood–milk ...
Hongmei Zhu, Qianqian Jia, Yanyan Zhang, Dongming Liu, Diqi Yang, Li Han, Jianguo Chen, Yi Ding   +7 more
doaj   +1 more source

Inhibition of hepatitis C virus infection by anti‐claudin‐1 antibodies is mediated by neutralization of E2–CD81–Claudin‐1 associations† [PDF]

Hepatology, 2010
The tight junction protein claudin-1 (CLDN1) has been shown to be essential for hepatitis C virus (HCV) entry-the first step of viral infection. Due to the lack of neutralizing anti-CLDN1 antibodies, the role of CLDN1 in the viral entry process is poorly understood.
Krieger, Sophie, Zeisel, Mirjam, Davis, Christopher, Thumann, Christine, Harris, Helen, Schnober, Eva, Mee, Christopher, Soulier, Eric, Royer, Cathy, Lambotin, Mélanie, Grunert, Fritz, Dao Thi, Viet Loan, Dreux, Marlène, François-Loïc, Cosset, Mckeating, Jane, Schuster, Catherine, Baumert, Thomas   +16 more
openaire   +7 more sources

The impact of CLAUDIN-1 on follicular thyroid carcinoma aggressiveness [PDF]

Endocrine-Related Cancer, 2015
CLAUDIN-1 belongs to the family of transmembrane tight junction proteins tightening the paracellular cleft of epithelial cells. In human malignancies, CLAUDIN-1 is often dysregulated and located in subcellular compartments, particularly in the nucleus where it may influence cellular behaviour.
Zwanziger, Denise, Badziong, Julia, Ting, Saskia, Möller, Lars, Kurt Werner, Schmid, Siebolts, Udo, Wickenhauser, Claudia, Dralle, Henning, Führer, Dagmar   +8 more
openaire   +2 more sources

The Expression and Localization of ZO-1, Claudin 1, and Claudin 4 in the Pig Epididymis

Journal of Animal Reproduction and Biotechnology, 2019
Tight junctions are constituents of the blood–epididymis barrier that play roles in regulating the unidirectional transcellular transport of ions, water, and solutes to maintain optimal conditions for sperm maturation and storage. Claudin 1 (Cldn1) and 4
Yun-Jae Park, Bongki Kim
doaj   +1 more source

Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells. [PDF]

PLoS ONE, 2017
Claudin-2, ZO-1, and occludin are major components of tight junctions (TJs) in the proximal tubule. However, their roles in maintaining paracellular permeability as leaky epithelia have yet to be defined.To investigate the contributory role of TJ ...
Sua Kim, Gheun-Ho Kim
doaj   +1 more source

Claudin-1 expression in cervical cancer

Molecular and Clinical Oncology, 2017
Claudin-1 is a tight junction protein that has been demonstrated to be involved in tumorigenesis and tumor progression in various types of solid tumors. In the present study, the protein expression of claudin-1 in squamous cervical cancer tissues obtained from 106 patients was analyzed by immunohistochemistry.
Friederike, Hoellen, Annika, Waldmann, Constanze, Banz-Jansen, Uwe, Holtrich, Thomas, Karn, Martina, Oberländer, Jens K, Habermann, Mareike, Hörmann, Frank, Köster, Julika, Ribbat-Idel, Marc, Thill, Achim, Rody, Ahmed, El-Balat, Lars, Hanker   +13 more
openaire   +3 more sources

Claudin‐1 correlates with poor prognosis in lung adenocarcinoma [PDF]

Thoracic Cancer, 2016
BackgroundThis study was conducted to investigate the clinical significance ofclaudin‐1 (CLDN1) expression in patients with lung adenocarcinoma.MethodsWe examinedCLDN1protein expression by immunohistochemistry in a tissue microarray from 258 patients with lung adenocarcinoma.
Sun, Bing‐sheng, Yao, Yi‐qun, Pei, Bao‐xiang, Zhang, Zhen‐fa, Wang, Chang‐li   +4 more
openaire   +2 more sources

Claudin-1 protein expression levels determined by western blot. [PDF]

, 2016
The relative folds changes of Claudin-1 in the SO, CPB, MHCA and DHCA groups were 1.000 ± 0.130, 0.992 ± 0.069, 0.956 ± 0.062 and 0.784 ± 0.054, respectively. Mean ± SD; n = 5. **P < 0.05 DHCA vs. CPB; ^ P < 0.05 DHCA vs. MHCA.
Mengya Liang (3186129), Zhixian Tang (3186135), Xiao Yang (19898), Jian Rong (598108), Weibin Lin (3186132), Guangxian Chen (3186126), Zhongkai Wu (2287063), Kangni Feng (3186123)   +7 more
core   +1 more source