Results 51 to 60 of about 21,285,591 (295)
Development of claudin‐1‐specific ligand
The FASEB Journal, 2013 Claudins (CLs) are a family of tetratransmembrane proteins consisting of 27 members and are potential targets for enhancing mucosal drug absorption, treating cancer, and mucosal vaccination using the C‐terminal fragment of Clostridium perfringens enterotoxin (C‐CPE), a CL‐3/‐4 binder.
Shotaro Nagase +6 more
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Expression of Tight Junction Protein Claudin-1 in Human Crescentic Glomerulonephritis
International Journal of Nephrology, 2014 The origin of crescent forming cells in human glomerulonephritis (GN) remains unknown. Some animal studies demonstrated that parietal epithelial cells of Bowman’s capsule (PECs) were the main component of proliferating cells and PEC-specific tight ...
Ryo Koda +8 more
doaj +1 more source
Immunocytochemical Localization of Claudin-1 in the Maturation Ameloblasts of Rat Incisors [PDF]
Frontiers in Physiology, 2010 Claudin-1 is a tight junction transmembrane protein. Its localization in the maturation ameloblasts of rat incisors was examined by immunofluorescence microscopy. Distal junction area of ruffle-ended ameloblasts (RA) and the Golgi apparatus of a sub-population of smooth-ended ameloblasts (SA) and RAs stained positive with anti-claudin-1 antibodies ...
Nishikawa, Sumio, Abe, Michio
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Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells
BMC Cancer, 2010 Background Claudin-1 is a membrane protein of tight junctions, and is associated with the development of various cancers. However, the significance of claudin-1 expression in cancer cells is not well understood.
Liu Yang +8 more
doaj +1 more source
Production, purification and characterization of recombinant, full-length human claudin-1.
PLoS ONE, 2013 The transmembrane domain proteins of the claudin superfamily are the major structural components of cellular tight junctions. One family member, claudin-1, also associates with tetraspanin CD81 as part of a receptor complex that is essential for ...
Nicklas Bonander +13 more
doaj +1 more source
Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions
Nature Communications, 2016 Alcohol abuse is a risk factor for acute respiratory distress syndrome, flooding of the lungs due to compromised barrier function. Here the authors report that alcohol upregulates claudin-5 that is then recruited to tight junctions in alveolar epithelial
Barbara Schlingmann +9 more
doaj +1 more source
Translational Oncology, 2019 Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression.
Anne A. Blanchard +10 more
doaj +1 more source
Scientific Reports, 2023 Next to the skin, the peritoneum is the largest human organ, essentially involved in abdominal health and disease states, but information on peritoneal paracellular tight junctions and transcellular channels and transporters relative to peritoneal ...
Eszter Levai +15 more
doaj +1 more source
Hepatology, EarlyView., 2022 KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou +15 more
wiley +1 more source
Loss of expression of claudin-1 in psoriasis is associated with proliferative state of keratinocytes
Indian Journal of Dermatopathology and Diagnostic Dermatology, 2020 Background: Psoriasis is a chronic remitting and relapsing inflammatory disease, with a prevalence of 0.44%–2.5% and is characterized by T-cell-mediated rapid turnover of epithelial cells.
Manoj Gopal Madakshira +2 more
doaj +1 more source