Results 191 to 200 of about 79,602 (359)

Changes in the Expression and Distribution of Claudins, Increased Epithelial Apoptosis, and a Mannan-Binding Lectin-Associated Immune Response Lead to Barrier Dysfunction in Dextran Sodium Sulfate-Induced Rat Colitis

open access: yesGut and Liver, 2015
Background/AimsThis animal study aimed to define the underlying cellular mechanisms of intestinal barrier dysfunction.Methods : Rats were fed 4% with dextran sodium sulfate (DSS) to induce experimental colitis.
doaj   +1 more source

mRNA and protein expression levels of claudin-16 and claudin-19.

open access: yes, 2013
a) Effect of cisplatin on renal mRNA expression levels of tight junction proteins claudin-16 and claudin-19. b) Expression of claudin-16 and claudin-19 protein in kidney tissue of rats was examined with Western blot analyses using claudin-16 and claudin ...
Gaëlle A. Boulet (209386)   +4 more
core   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

open access: yesExploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi   +5 more
wiley   +1 more source

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

open access: yesFlavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang   +3 more
wiley   +1 more source

Bibliothèque facétieuse historique et singulière ou Réimpression de pièces curieuses, rares ou peu connues des XVe, XVIe et XVIIe siècles / [publiée par A. Claudin]

open access: yes
Comprend : Regrets funèbres sur la mort du joyeux Rondibilis dont tous les honnestes goinfres sont obligez d'en solenniser la mémoire ; Sur l'enlèvement des reliques de sainct Fiacre apportées de la ville de Meaux pour la guérison du Q de Mr le cardinal ...
Gaultier Garguille (1573?-1633). Auteur du texte   +1 more
core  

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

open access: yesFood Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Evaluation of Claudin-1 and Claudin-4 immunreaktivity at benign, premalign and malign lesions of prostate [PDF]

open access: yes, 2009
YÖK Tez No: 236326Amaç: Prostat karsinomları erkeklerde en sık görülen malignitedir. Yasam süresinin uzamasıve yardımcı tanı yöntemleri ile prostat adenokarsinomlarının sıklıgı artmıstır.
Önal, Ali Can
core  

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