Apoptotic Fragmentation of Tricellulin [PDF]
International Journal of Molecular Sciences, 2019 Apoptotic extrusion of cells from epithelial cell layers is of central importance for epithelial homeostasis. As a prerequisite cell–cell contacts between apoptotic cells and their neighbors have to be dissociated. Tricellular tight junctions (tTJs)
Otmar Huber
exaly +6 more sources
Loss of tricellular tight junction tricellulin leads to hyposalivation in Sjögren’s syndrome [PDF]
International Journal of Oral ScienceTricellulin, a key tricellular tight junction (TJ) protein, is essential for maintaining the barrier integrity of acinar epithelia against macromolecular passage in salivary glands.
Xiangdi Mao +9 more
doaj +4 more sources
Loss of Occludin Affects Tricellular Localization of Tricellulin [PDF]
Molecular Biology of the Cell, 2008 The tricellular tight junction (tTJ) forms at the convergence of bicellular tight junctions (bTJs) where three epithelial cells meet in polarized epithelia, and it is required for the maintenance of the transepithelial barrier. Tricellulin is a four transmembrane domain protein recently identified as the first marker of tTJ, but little is known about ...
Junichi Ikenouchi +2 more
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Tricellulin Effect on Paracellular Water Transport [PDF]
International Journal of Molecular Sciences, 2019 In epithelia, large amounts of water pass by transcellular and paracellular pathways, driven by the osmotic gradient built up by the movement of solutes. The transcellular pathway has been molecularly characterized by the discovery of aquaporin membrane channels. Unlike this, the existence of a paracellular pathway for water through the tight junctions
Carlos Ayala-Torres +2 more
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The Role of Tricellulin in Epithelial Jamming and Unjamming via Segmentation of Tricellular Junctions [PDF]
Advanced Science, 2020 Collective cellular behavior in confluent monolayers supports physiological and pathological processes of epithelial development, regeneration, and carcinogenesis. Here, the attainment of a mature and static tissue configuration or the local reactivation
Sophie Lohmann +7 more
doaj +6 more sources
Contribution of the tricellular tight junction proteins, tricellulin and angulin-1, to paracellular water permeability [PDF]
Journal of Cell Biology, 2021 In epithelia, large amounts of water pass by transcellular and paracellular pathways, driven by the osmotic gradient built up by solutes’ movement.
Ayala Torres, Carlos Mario
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Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin [PDF]
Particle and Fibre Toxicology, 2020 Background While exposure to diesel exhaust particles has been linked to aberrant immune responses in allergic diseases such as asthma, little attention has been paid to their effects on the airway epithelial barrier.
Timothy Smyth +5 more
doaj +3 more sources
Looking at tricellulin expression in the brain [PDF]
, 2010 Tese de mestrado. Biologia (Biologia Molecular e Genética). Universidade de Lisboa, Faculdade de Ciências, 2010It was recently reported the existence of a protein, called tricellulin (TRIC), concentrated at tricellular tight junctions (TJ) but also ...
Mariano, Cibelle Neiva Cavalcanti, 1984-
core +2 more sources
Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells [PDF]
Biology Open, 2014 Occludin is the first identified protein in the tight junction (TJ), but its function has remained for the most part obscure. TJs have been demonstrated to play important roles in the inner ear function, and occludin is expressed in all the epithelial ...
Shin-ichiro Kitajiri +5 more
doaj +3 more sources
Tricellulin Expression and its Prognostic Significance in Primary Liver Carcinomas
Pathology and Oncology Research, 2014 Numerous data suggest that altered expression of tight junction proteins such as occludin and claudins plays important role in carcinogenesis. However, little is known about tricellulin, a transmembrane tight junction protein concentrated where three epithelial cells meet. We aimed to characterize tricellulin expression in normal and cirrhotic liver in
Áron Somorácz +2 more
exaly +4 more sources