Results 1 to 10 of about 80,524 (163)
Biomedicines, 2023 (1) Introduction: Claudin-9 (CLDN9) is a member of the claudin protein family, a critical transmembrane protein family for tight junctions that are implemented in the progression of numerous cancer types.
Xinguo Zhuang +8 more
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Polish Journal of Pathology, 2022 We investigated the expression of claudin 6 in non-small-cell lung carcinomas (NSCLC) by immunohistochemistry. Samples of 164 patients with NSCLC were studied by immunohistochemistry. Claudin 6 was expressed in 42 % of cases.
Ylermi Soini +4 more
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Toxins, 2023 Background: Clostridioides difficile binary toxin (CDT) defines the hypervirulence of strains in nosocomial antibiotic-induced colitis with the highest mortality.
Lucas Heils +4 more
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Context-Dependent Roles of Claudins in Tumorigenesis
Frontiers in Oncology, 2021 The barrier and fence functions of the claudin protein family are fundamental to tissue integrity and human health. Increasing evidence has linked claudins to signal transduction and tumorigenesis. The expression of claudins is frequently dysregulated in
Jian Li
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Developmental expression of claudins in the mammary gland [PDF]
, 2017 Claudins are a large family of membrane proteins whose classic function is to regulate the permeability of tight junctions in epithelia. They are tetraspanins, with four alpha-helices crossing the membrane, two extracellular loops, a short cytoplasmic N ...
Baumgartner, Heidi K. +8 more
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Human Claudin-7 cis-Interactions Are Not Crucial for Membrane-Membrane (Trans-) Interactions
Frontiers in Molecular Biosciences, 2022 Human Claudin-7 (Cldn7) is a member of the Claudin (Cldn) superfamily. In vivo, these proteins form tight junctions, which establish constricted connections between cells. Cldns oligomerize within the membrane plane (= cis-interaction), and also interact
Lena Ahlswede +5 more
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Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion [PDF]
, 2017 Thousands of genes have been well demonstrated to play important roles in cancer progression. As genes do not function in isolation, they can be grouped into “networks” based on their interactions.
Chen, Xiao-wan +9 more
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Physiological Reports, 2023 Using the 16HBE 14o‐ human airway epithelial cell culture model, calcitriol (Vitamin D) was shown to improve barrier function by two independent metrics – increased transepithelial electrical resistance (TER) and reduced transepithelial diffusion of 14C ...
Elizabeth Rybakovsky +6 more
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VE-cadherin and claudin-5: it takes two to tango [PDF]
, 2008 Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively.
A Taddei +17 more
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The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]
, 2009 The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Bracarense, Ana-Paula +8 more
core +2 more sources