Results 21 to 30 of about 56,637 (316)
La libertad de prensa encarcelada. Informar mata
Con la única referencia de "Reporteros sin fronteras" se afirma que la libertad de prensa no está garantizada en más de la mitad de los países del mundo.
Rafael Jiménez Claudín
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Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk
The ability of epithelial cells to organize through cell–cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions (TJ), adherens junctions (AJ),
Ajaz A. Bhat +10 more
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Quercetin improves and protects Calu-3 airway epithelial barrier function
Introduction: In light of the impact of airway barrier leaks in COVID-19 and the significance of vitamin D in COVID-19 outcomes, including airway barrier protection, we investigated whether the very common dietary flavonoid quercetin could also be ...
K. M. DiGuilio +8 more
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Claudins are a family of tight junction membrane proteins that regulate paracellular permeability of epithelia, likely by forming the lining of the paracellular pore. Claudins are expressed throughout the renal tubule, and mutations in two claudin genes are now known to cause familial hypercalciuric hypomagnesemia with nephrocalcinosis. In this review,
Susanne, Angelow +2 more
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Claudins are a multigene transmembrane protein family comprising at least 27 members. In gastrointestinal tract, claudins are mainly located in the intestinal epithelia; many types of claudins form a network of strands in tight junction plaques within ...
Liguo Zhu +5 more
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The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling
Cell adhesion molecules, including integrins, cadherins, and claudins (CLDNs), are known to activate Src-family kinases (SFKs) that organize a variety of physiological and pathological processes; however, the underlying molecular basis remains unclear ...
Naoki Ichikawa-Tomikawa +3 more
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Claudins in teleost fishes [PDF]
Teleost fishes are a large and diverse animal group that represent close to 50% of all described vertebrate species. This review consolidates what is known about the claudin (Cldn) family of tight junction (TJ) proteins in teleosts. Cldns are transmembrane proteins of the vertebrate epithelial/endothelial TJ complex that largely determine TJ ...
Kolosov, Dennis +3 more
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Due to the lack of timely and accurate screening modalities and treatments, most pancreatic cancer (PCa) patients undergo fatal PCa progression within a short period since diagnosis. The claudin(CLDN) family is expressed specifically as tight junction structure in a variety of tumors, including PCa, and affects tumor progression by changing the cell ...
Chen Wang +5 more
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Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins
The anadromous salmonid life cycle includes both fresh water (FW) and seawater (SW) stages. The parr-smolt transformation (smoltification) pre–adapt the fish to SW while still in FW.
Kristina eSundell, Henrik eSundh
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The homologs EpCAM and TROP2, which both interact with claudin-1 and claudin-7, are frequently coexpressed in epithelia including skin. Intestine uniquely expresses high levels of EpCAM but not TROP2.
Chuan-Jin Wu +4 more
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