Results 21 to 30 of about 80,593 (229)

Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

open access: yesFrontiers in Physiology, 2019
The ability of epithelial cells to organize through cell–cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions (TJ), adherens junctions (AJ),
Ajaz A. Bhat   +10 more
doaj   +1 more source

Quercetin improves and protects Calu-3 airway epithelial barrier function

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: In light of the impact of airway barrier leaks in COVID-19 and the significance of vitamin D in COVID-19 outcomes, including airway barrier protection, we investigated whether the very common dietary flavonoid quercetin could also be ...
K. M. DiGuilio   +8 more
doaj   +1 more source

Claudins and the Kidney [PDF]

open access: yesJournal of the American Society of Nephrology, 2015
Claudins are tight-junction membrane proteins that function as both pores and barriers in the paracellular pathway in epithelial cells. In the kidney, claudins determine the permeability and selectivity of different nephron segments along the renal tubule. In the proximal tubule, claudins have a role in the bulk reabsorption of salt and water.
openaire   +2 more sources

Claudin Family Participates in the Pathogenesis of Inflammatory Bowel Diseases and Colitis-Associated Colorectal Cancer

open access: yesFrontiers in Immunology, 2019
Claudins are a multigene transmembrane protein family comprising at least 27 members. In gastrointestinal tract, claudins are mainly located in the intestinal epithelia; many types of claudins form a network of strands in tight junction plaques within ...
Liguo Zhu   +5 more
doaj   +1 more source

The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling

open access: yesCells, 2023
Cell adhesion molecules, including integrins, cadherins, and claudins (CLDNs), are known to activate Src-family kinases (SFKs) that organize a variety of physiological and pathological processes; however, the underlying molecular basis remains unclear ...
Naoki Ichikawa-Tomikawa   +3 more
doaj   +1 more source

Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins

open access: yesFrontiers in Physiology, 2012
The anadromous salmonid life cycle includes both fresh water (FW) and seawater (SW) stages. The parr-smolt transformation (smoltification) pre–adapt the fish to SW while still in FW.
Kristina eSundell, Henrik eSundh
doaj   +1 more source

Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins

open access: yesCells, 2020
The homologs EpCAM and TROP2, which both interact with claudin-1 and claudin-7, are frequently coexpressed in epithelia including skin. Intestine uniquely expresses high levels of EpCAM but not TROP2.
Chuan-Jin Wu   +4 more
doaj   +1 more source

Transport relaxation time and length scales in turbulent suspensions [PDF]

open access: yes, 2010
We show that in a turbulent flow transporting suspended sediment, the unsaturated sediment flux $q(x,t)$ can be described by a first-order relaxation equation.
Andreotti, B., Charru, F., Claudin, P.
core   +1 more source

Endomicroscopic and transcriptomic analysis of impaired barrier function and malabsorption in environmental enteropathy [PDF]

open access: yes, 2016
Introduction: Environmental enteropathy (EE) is associated with growth failure, micronutrient malabsorption and impaired responses to oral vaccines.
A Prendergast   +61 more
core   +10 more sources

Which Russia, twenty years later? [PDF]

open access: yesRevista CIDOB d'Afers Internacionals, 2011
Russia is proud of its position among the emerging powers, of the strength provided by its ample energetic resources and its nuclear potential with which it can influence the world and always be taken into account. Nevertheless, the perception within the
Carmen Claudín
doaj  

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