Results 21 to 30 of about 56,637 (316)

La libertad de prensa encarcelada. Informar mata

open access: yesChasqui, 2015
Con la única referencia de "Reporteros sin fronteras" se afirma que la libertad de prensa no está garantizada en más de la mitad de los países del mundo.
Rafael Jiménez Claudín
doaj   +1 more source

Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

open access: yesFrontiers in Physiology, 2019
The ability of epithelial cells to organize through cell–cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions (TJ), adherens junctions (AJ),
Ajaz A. Bhat   +10 more
doaj   +1 more source

Quercetin improves and protects Calu-3 airway epithelial barrier function

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: In light of the impact of airway barrier leaks in COVID-19 and the significance of vitamin D in COVID-19 outcomes, including airway barrier protection, we investigated whether the very common dietary flavonoid quercetin could also be ...
K. M. DiGuilio   +8 more
doaj   +1 more source

Biology of claudins

open access: yesAmerican Journal of Physiology-Renal Physiology, 2008
Claudins are a family of tight junction membrane proteins that regulate paracellular permeability of epithelia, likely by forming the lining of the paracellular pore. Claudins are expressed throughout the renal tubule, and mutations in two claudin genes are now known to cause familial hypercalciuric hypomagnesemia with nephrocalcinosis. In this review,
Susanne, Angelow   +2 more
openaire   +3 more sources

Claudin Family Participates in the Pathogenesis of Inflammatory Bowel Diseases and Colitis-Associated Colorectal Cancer

open access: yesFrontiers in Immunology, 2019
Claudins are a multigene transmembrane protein family comprising at least 27 members. In gastrointestinal tract, claudins are mainly located in the intestinal epithelia; many types of claudins form a network of strands in tight junction plaques within ...
Liguo Zhu   +5 more
doaj   +1 more source

The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling

open access: yesCells, 2023
Cell adhesion molecules, including integrins, cadherins, and claudins (CLDNs), are known to activate Src-family kinases (SFKs) that organize a variety of physiological and pathological processes; however, the underlying molecular basis remains unclear ...
Naoki Ichikawa-Tomikawa   +3 more
doaj   +1 more source

Claudins in teleost fishes [PDF]

open access: yesTissue Barriers, 2013
Teleost fishes are a large and diverse animal group that represent close to 50% of all described vertebrate species. This review consolidates what is known about the claudin (Cldn) family of tight junction (TJ) proteins in teleosts. Cldns are transmembrane proteins of the vertebrate epithelial/endothelial TJ complex that largely determine TJ ...
Kolosov, Dennis   +3 more
openaire   +2 more sources

Claudin and pancreatic cancer

open access: yesFrontiers in Oncology, 2023
Due to the lack of timely and accurate screening modalities and treatments, most pancreatic cancer (PCa) patients undergo fatal PCa progression within a short period since diagnosis. The claudin(CLDN) family is expressed specifically as tight junction structure in a variety of tumors, including PCa, and affects tumor progression by changing the cell ...
Chen Wang   +5 more
openaire   +3 more sources

Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins

open access: yesFrontiers in Physiology, 2012
The anadromous salmonid life cycle includes both fresh water (FW) and seawater (SW) stages. The parr-smolt transformation (smoltification) pre–adapt the fish to SW while still in FW.
Kristina eSundell, Henrik eSundh
doaj   +1 more source

Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins

open access: yesCells, 2020
The homologs EpCAM and TROP2, which both interact with claudin-1 and claudin-7, are frequently coexpressed in epithelia including skin. Intestine uniquely expresses high levels of EpCAM but not TROP2.
Chuan-Jin Wu   +4 more
doaj   +1 more source

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