Results 21 to 30 of about 79,602 (359)
Journal of the American Society of Nephrology, 2022 Significance Statement Claudin-10 is a tight junction protein expressed along the nephron. The claudin-10a isoform is a paracellular anion channel; claudin-10b facilitates paracellular Na+ transport in the thick ascending limb.
T. Breiderhoff +23 more
semanticscholar +1 more source
Claudin-Low Breast Cancer; Clinical & Pathological Characteristics. [PDF]
, 2017 Claudin-low breast cancer is a molecular type of breast cancer originally identified by gene expression profiling and reportedly associated with poor survival. Claudin-low tumors have been recognised to preferentially display a triple-negative phenotype,
John Hassell +17 more
core +1 more source
Claudins in teleost fishes [PDF]
Tissue Barriers, 2013 Teleost fishes are a large and diverse animal group that represent close to 50% of all described vertebrate species. This review consolidates what is known about the claudin (Cldn) family of tight junction (TJ) proteins in teleosts. Cldns are transmembrane proteins of the vertebrate epithelial/endothelial TJ complex that largely determine TJ ...
Kolosov, Dennis +3 more
openaire +2 more sources
La libertad de prensa encarcelada. Informar mata
Chasqui, 2015 Con la única referencia de "Reporteros sin fronteras" se afirma que la libertad de prensa no está garantizada en más de la mitad de los países del mundo.
Rafael Jiménez Claudín
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Significant calcium absorption across renal and intestinal epithelia occurs via the paracellular pathway. However, the identity of the paracellular pore involved is unknown.
Megan R Beggs +10 more
semanticscholar +1 more source
SUMOylation of claudin-2: SUMOylation of claudin-2 [PDF]
Annals of the New York Academy of Sciences, 2012 The C‐terminal cytoplasmic tails of claudins are likely sites for interaction with proteins that regulate their function. We performed a yeast two‐hybrid screen with the tail of human claudin‐2 against a human kidney cDNA library and identified interactions with the PDZ3 domain of ZO‐2 as well as ubiquitin‐conjugating enzyme E2I (SUMO ligase‐1) and E3 ...
Van Itallie, Christina M. +2 more
openaire +3 more sources
Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk
Frontiers in Physiology, 2019 The ability of epithelial cells to organize through cell–cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions (TJ), adherens junctions (AJ),
Ajaz A. Bhat +10 more
doaj +1 more source
Quercetin improves and protects Calu-3 airway epithelial barrier function
Frontiers in Cell and Developmental Biology, 2023 Introduction: In light of the impact of airway barrier leaks in COVID-19 and the significance of vitamin D in COVID-19 outcomes, including airway barrier protection, we investigated whether the very common dietary flavonoid quercetin could also be ...
K. M. DiGuilio +8 more
doaj +1 more source
Claudin-5: gatekeeper of neurological function
Fluids and Barriers of the CNS, 2019 Tight junction proteins of the blood–brain barrier are vital for maintaining integrity of endothelial cells lining brain blood vessels. The presence of these protein complexes in the space between endothelial cells creates a dynamic, highly regulated and
C. Greene, N. Hanley, M. Campbell
semanticscholar +1 more source
Journal of Crohn's & Colitis, 2021 BACKGROUND AND AIMS Dysfunction of the vitamin D receptor (VDR) contributes to the etiology of IBD by regulating autophagy, immune response, and mucosal permeability. VDR directly controls the paracellular tight junction protein Claudin-2.
I. Chatterjee +5 more
semanticscholar +1 more source