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Ergot alkaloids (EAs) are a group of mycotoxins that are mainly produced from the plant pathogen Claviceps. Claviceps purpurea is one of the most important species, being a major producer of EAs that infect more than 400 species of monocotyledonous ...
Sofia Agriopoulou
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The Biological Roles of Class II Hydrophobins at the Cell Wall of Filamentous Ascomycetes
ABSTRACT One of the most elusive aspects of fungal cell wall biology has been dilucidating the specific functions of most cell wall proteins. Class II hydrophobins are small amphipathic proteins produced exclusively by filamentous ascomycetes. A comparative synthesis of their biological functions across species has been lacking for this specific group ...
Wilhelm Hansberg, Omar Páez
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An endophytic fungus (Daldinia sp.) was isolated from the leaves of Avicennia officinalis collected from mangrove forests of Goa. The ethyl acetate extract of Avicennia officinalis (AO‐EA) of the identified endophyte demonstrated antibacterial and antibiofilm activity against Escherichia coli and Shigella sp.
Nickita Dutta +3 more
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In LPS‐induced Caco‐2 cells, EGT inhibits inflammatory cytokine overproduction and restores tight‐junction proteins. In DSS‐induced colitis mice, EGT alleviates colitis symptoms, lowers inflammatory mediators and immunoglobulins, and remodels gut microbiota.
Lin Wang +6 more
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Ergot sclerotia effect cereal crops intended for consumption. Ergot alkaloids within ergot sclerotia are assessed to ensure contamination is below safety standards established for human and animal health.
Jensen Cherewyk +3 more
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Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease
Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi +6 more
wiley +1 more source
Additional file S8. Orthofinder results based on Claviceps species PSP. Orthofinder results based on the PSP of C. purpurea and C.
H. Oberti (8261559) +6 more
core +1 more source
Effect of Field-applied Fungicides on Claviceps purpurea Sclerotia and Associated Toxins in Wheat
Claviceps purpurea (Fr.) Tul is the causal organism for ergot impacting grass hosts, including wheat. The pathogen produces ergot alkaloids (EAs) during the development of mature sclerotia leading to potential wheat quality discounts or rejection at the ...
Shatha Alaoufi +2 more
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Abstract Dihydroergotamine (DHE) prescribing information contains a boxed warning regarding the possibility of serious and/or life‐threatening peripheral ischemia with co‐administration of strong cytochrome P450 3A4 (CYP3A4) inhibitors. The effects of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics and safety of nasally administered ...
Detlef Albrecht +2 more
wiley +1 more source
Using a strain of Claviceps purpurea which produces under submerged conditions chanoclavine, ergometrine and mainly ergotoxine the biosynthesis of ergoline derivatives has been studied. DL-Tryptophan- (ring-2-14C) is specifically incorporated into the lysergic acid moiety of ergotoxine· alkaloids.
D. Gröger, D. Erge
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