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Immune classification of clear cell renal cell carcinoma [PDF]

open access: yesScientific Reports, 2021
Since the outcome of treatments, particularly immunotherapeutic interventions, depends on the tumor immune micro-environment (TIM), several experimental and computational tools such as flow cytometry, immunohistochemistry, and digital cytometry have been
Sumeyye Su   +2 more
doaj   +5 more sources

Clear Cell Papillary Renal Cell Carcinoma [PDF]

open access: yesArchives of Pathology & Laboratory Medicine, 2019
Clear cell papillary renal cell carcinoma (ccpRCC) is a recently recognized entity and represents the fourth most common variant of renal cell carcinoma (RCC). It has unique morphologic and immunohistochemical features and demonstrates an indolent clinical behavior.
Jianping, Zhao, Eduardo, Eyzaguirre
openaire   +3 more sources

LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway

open access: yesCells, 2022
ccRCC is highly immunogenic, yet its underlying immune-related molecular mechanisms are unknown. Leukotriene B4 Receptor 1 (LTB4R), a novel immune-related gene associated in our previous research with the prognosis of ccRCC patients, has been found in ...
Xiao Zhang   +4 more
doaj   +1 more source

Prognostic significance of CKAP2L expression in patients with clear cell renal cell carcinoma

open access: yesFrontiers in Genetics, 2023
Background: Cytoskeleton-associated protein 2-like protein (CKAP2L) is thought to promote the progression of glioma, breast cancer, and ovarian cancer. However, the role of cytoskeleton-associated protein 2-like protein in clear cell renal cell carcinoma
Zhi Liu   +6 more
doaj   +1 more source

Renal Lipid Metabolism Abnormalities in Obesity and Clear Cell Renal Cell Carcinoma

open access: yesMetabolites, 2021
Clear cell renal cell carcinoma is the most common and deadly type of cancer affecting the kidney, and is characterized histologically by large intracellular lipid deposits.
Ion Alexandru Bobulescu   +8 more
doaj   +1 more source

Genetics and Tumor Microenvironment of Renal Cell Carcinoma

open access: yesSociété Internationale d’Urologie Journal, 2022
Renal cell carcinoma is a diverse group of diseases that can be distinguished by distinct histopathologic and genomic features. In this comprehensive review, we highlight recent advancements in our understanding of the genetic and microenvironmental ...
Sari Khaleel   +7 more
doaj   +1 more source

HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma [PDF]

open access: yes, 2016
Indexación: Web of ScienceBackground: Class I histone deacetylases (HDACs) have been reported to be overexpressed in clear cell renal cell carcinoma (ccRCC), whereas the expression of class II HDACs is unknown.
Attwood, Kris   +14 more
core   +4 more sources

Clear Cell Renal Cell Carcinoma: Local Recurrence and Bilateral Adrenal Metastases - A Case Report

open access: yesJournal of the Belgian Society of Radiology, 2022
Introduction: Clear cell renal cell carcinoma is the most frequent type of renal cell carcinoma, which is often diagnosed incidentally in an advanced stage.
Eliza-Maria Popa   +2 more
doaj   +1 more source

Role of tumor-derived exosomes in metastasis, drug resistance and diagnosis of clear cell renal cell carcinoma

open access: yesFrontiers in Oncology, 2022
Renal cancer is one of the most extensively studied human tumors today, with clear cell renal cell carcinoma accounting for approximately 80% of all cases.
Tiancheng Jiang   +9 more
doaj   +1 more source

Radiogenomics in clear cell renal cell carcinoma: correlations between advanced CT imaging (texture analysis) and microRNAs expression [PDF]

open access: yes, 2019
Purpose: A relevant challenge for the improvement of clear cell renal cell carcinoma management could derive from the identification of novel molecular biomarkers that could greatly improve the diagnosis, prognosis, and treatment choice of these ...
Badia, S.   +12 more
core   +1 more source

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