Results 11 to 20 of about 367,353 (219)

Clear Cell Renal Cell Carcinoma [PDF]

open access: yesRadiopaedia.org, 2020
These are also called as Environmental cells; these are having a pale appearance, with 70% individuals and renal cell cancer, the growth of this type of cell are either be fast or be slow.
null Sarah Bastawrous   +2 more
semanticscholar   +7 more sources

Metabolic reprogramming of clear cell renal cell carcinoma

open access: yesFrontiers in Endocrinology, 2023
Clear cell renal cell carcinoma (ccRCC) is a malignancy that exhibits metabolic reprogramming as a result of genetic mutations. This reprogramming accommodates the energy and anabolic needs of the cancer cells, leading to changes in glucose, lipid, and ...
Haiyan Zhu   +3 more
doaj   +2 more sources

Pembrolizumab versus placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma (KEYNOTE-564): 30-month follow-up analysis of a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

open access: yesThe Lancet Oncology, 2022
BACKGROUND The first interim analysis of the KEYNOTE-564 study showed improved disease-free survival with adjuvant pembrolizumab compared with placebo after surgery in patients with clear cell renal cell carcinoma at an increased risk of recurrence.
T. Powles   +222 more
semanticscholar   +1 more source

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

open access: yes, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA   +8 more
core   +2 more sources

Phase II Trial of Cabozantinib Plus Nivolumab in Patients With Non–Clear-Cell Renal Cell Carcinoma and Genomic Correlates

open access: yesJournal of Clinical Oncology, 2022
PURPOSE To assess the efficacy and safety of cabozantinib plus nivolumab in a phase II trial in patients with non–clear-cell renal cell carcinoma (RCC).
Chung-Han Lee   +17 more
semanticscholar   +1 more source

Clinical utility of MCM2 and CD44 expression in clear cell renal cell carcinoma

open access: yesPolish Journal of Pathology, 2021
Clear cell renal cell carcinoma (ccRCC) has an unpredictable clinical consequence even with the use of usual prognostic factors. To determine whether utilization of cell proliferation and cell adhesion by using MCM2 and CD44 immuno-expression could ...
Mariana F. Gayyed   +2 more
doaj   +1 more source

A Positive Feedback Loop between Inactive VHL-Triggered Histone Lactylation and PDGFRβ Signaling Drives Clear Cell Renal Cell Carcinoma Progression

open access: yesInternational Journal on Biological Sciences, 2022
Inactive von Hippel-Lindau (VHL) is linked to metabolic reprogramming and plays pivotal roles in the pathogenesis of clear cell renal cell carcinoma (ccRCC).
Jiefeng Yang   +13 more
semanticscholar   +1 more source

Ipsilateral synchronous clear and papillary renal cell carcinoma: A case report and review of the literature

open access: yesUrology Case Reports, 2018
Clear cell renal cell carcinoma and papillary renal cell carcinoma are the most common types of renal tumors. However, coexistence of both tumors in the same kidney is a rare condition.We report a 56-year old male who was found to have ipsilateral ...
Muna Alhusban   +3 more
doaj   +1 more source

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