Results 11 to 20 of about 337,050 (372)
Establishment of patient-derived three-dimensional organoid culture in renal cell carcinoma [PDF]
Investigative and Clinical Urology, 2020 Purpose: Renal cell carcinoma is a heterogeneous kidney cancer, and over 403,000 cases were reported worldwide in 2018. Current methods for studying renal cell carcinoma are limited to two-dimensional (2D) culture of primary cell lines and patient ...
Joon Chae Na +9 more
doaj +4 more sources
Clear cell renal cell carcinoma
Radiopaedia.org, 2017 Vikas Shah, Bruno Paulino Di Muzio
semanticscholar +3 more sources
Sorafenib in advanced clear-cell renal-cell carcinoma.
New England Journal of Medicine, 2007 BACKGROUND We conducted a phase 3, randomized, double-blind, placebo-controlled trial of sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients with advanced clear-cell renal-cell carcinoma.
B. Escudier +18 more
semanticscholar +4 more sources
BIGH3 is overexpressed in clear cell renal cell carcinoma
Oncology Reports, 2008 To identify new target marker genes in renal cell carcinoma (RCC), we compared the gene expression profiles of clear cell RCC (cc-RCC) and normal kidney tissue using serial analysis of gene expression. Our results revealed that the transforming growth factor beta induced 68 kDa protein (TGF-betaI: beta ig-h3 (BIGH3), plasminogen activator inhibitor-1 ...
Masanori YAMANAKA +6 more
openalex +5 more sources
Cells, 2022 ccRCC is highly immunogenic, yet its underlying immune-related molecular mechanisms are unknown. Leukotriene B4 Receptor 1 (LTB4R), a novel immune-related gene associated in our previous research with the prognosis of ccRCC patients, has been found in ...
Xiao Zhang +4 more
doaj +1 more source
Clear Cell Papillary Renal Cell Carcinoma [PDF]
Archives of Pathology & Laboratory Medicine, 2019 Clear cell papillary renal cell carcinoma (ccpRCC) is a recently recognized entity and represents the fourth most common variant of renal cell carcinoma (RCC). It has unique morphologic and immunohistochemical features and demonstrates an indolent clinical behavior.
Jianping Zhao, Eduardo Eyzaguirre
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Prognostic significance of CKAP2L expression in patients with clear cell renal cell carcinoma
Frontiers in Genetics, 2023 Background: Cytoskeleton-associated protein 2-like protein (CKAP2L) is thought to promote the progression of glioma, breast cancer, and ovarian cancer. However, the role of cytoskeleton-associated protein 2-like protein in clear cell renal cell carcinoma
Zhi Liu +6 more
doaj +1 more source
Genetics and Tumor Microenvironment of Renal Cell Carcinoma
Société Internationale d’Urologie Journal, 2022 Renal cell carcinoma is a diverse group of diseases that can be distinguished by distinct histopathologic and genomic features. In this comprehensive review, we highlight recent advancements in our understanding of the genetic and microenvironmental ...
Sari Khaleel +7 more
doaj +1 more source
Proteomics Characterization of Clear Cell Renal Cell Carcinoma
Journal of Clinical Medicine, 2023 Purpose: To explore the tumor proteome of patients diagnosed with localized clear cell renal cancer (ccRCC) and treated with surgery. Material and methods: A total of 165 FFPE tumor samples from patients diagnosed with ccRCC were analyzed using DIA-proteomics.
Jesús Miranda-Poma +14 more
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Cancers, 2023 Simple Summary The aim of the present review is to discuss novel prognostic and therapeutic markers for clear cell renal cell carcinoma, a subtype of renal cell carcinoma which is the most common variant and is characterized by high aggressiveness ...
Valentina Schiavoni +8 more
semanticscholar +1 more source