Results 21 to 30 of about 367,353 (219)

A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]

, 2015
Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio, Leto, Antonino, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Silvestri, Luigi   +6 more
core   +1 more source

Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline

Journal of Clinical Oncology, 2022
PURPOSE To provide recommendations for the management of patients with metastatic clear cell renal cell carcinoma (ccRCC). METHODS An Expert Panel conducted a systematic literature review to obtain evidence to guide treatment recommendations. RESULTS The
W. Rathmell, R. Rumble, P. V. Van Veldhuizen, H. Al-Ahmadie, H. Emamekhoo, R. Hauke, A. Louie, M. Milowsky, A. Molina, T. Rose, S. Siva, Nicholas G Zaorsky, Tian Zhang, R. Qamar, Terry M Kungel, Bryan Lewis, E. Singer   +16 more
semanticscholar   +1 more source

Nuclear Pedigree Criteria for the Identification of Individuals Suspected to be at Risk of an Inherited Predisposition to Renal Cancer [PDF]

, 2005
Renal clear cell carcinomas represent about 3% of all visceral cancers and account for approximately 85% of renal cancers in adults. Environmental and genetic factors are involved in the development of renal cancer.
Aleksandra Tołoczko-Grabarek, Andrzej Sikorski, Marek Brzosko, Jan Lubiński   +3 more
core   +2 more sources

A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma

Genes, 2022
Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, which is characterized by metabolic reprogramming. Cuproptosis, a novel form of cell death, is highly linked to mitochondrial metabolism and mediated by ...
Zilong Bian, Rong Fan, Lingmin Xie
semanticscholar   +1 more source

The long noncoding RNA urothelial carcinoma-associated 1 overexpression as a poor prognostic biomarker in clear cell renal cell carcinoma

Tumor Biology, 2017
Long noncoding RNA urothelial carcinoma-associated 1 has previously played important roles in cancer. However, its role is still unknown in clear cell renal cell carcinoma.
Yang Wang, Wen Gao, Jiali Xu, Yizhi Zhu, Lingxiang Liu   +4 more
doaj   +1 more source

Cellular milieu in clear cell renal cell carcinoma

Frontiers in Oncology, 2022
Clear cell renal cell carcinoma (ccRCC) is globally the most prevalent renal cancer. The cells of origin in ccRCC have been identified as proximal tubular epithelial cells (PTEC); however, the transcriptomic pathways resulting in the transition from ...
Arti M. Raghubar, Arti M. Raghubar, Arti M. Raghubar, Arti M. Raghubar, Arti M. Raghubar, Matthew J. Roberts, Matthew J. Roberts, Matthew J. Roberts, Matthew J. Roberts, Simon Wood, Simon Wood, Helen G. Healy, Helen G. Healy, Helen G. Healy, Andrew J. Kassianos, Andrew J. Kassianos, Andrew J. Kassianos, Andrew J. Mallett, Andrew J. Mallett, Andrew J. Mallett, Andrew J. Mallett   +20 more
doaj   +1 more source

Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness.

Cancer Cell, 2022
Clear cell renal cell carcinomas (ccRCCs) represent ∼75% of RCC cases and account for most RCC-associated deaths. Inter- and intratumoral heterogeneity (ITH) results in varying prognosis and treatment outcomes. To obtain the most comprehensive profile of
Yize Li, T. Lih, S. Dhanasekaran, R. Mannan, Lijun Chen, M. Cieslik, Yige Wu, Rita Jui-Hsien Lu, D. Clark, Iga Kołodziejczak, R. Hong, Siqi Chen, Yanyan Zhao, Seema Chugh, Wagma Caravan, Nataly Naser Al Deen, Noshad Hosseini, Chelsea J. Newton, Karsten Krug, Yuanwei Xu, Kyung-Cho Cho, Yingwei Hu, Yuping Zhang, Chandan Kumar-Sinha, Weiping Ma, A. Calinawan, Matthew A. Wyczalkowski, M. Wendl, Yuefan Wang, Shenghao Guo, Cissy Zhang, A. Le, Aniket Dagar, A. Hopkins, Hanbyul Cho, F. Leprevost, Xiaojun Jing, Guo Ci Teo, Wenke Liu, M. Reimers, R. Pachynski, A. Lazar, A. Chinnaiyan, B. V. Van Tine, Bing‐yu Zhang, K. Rodland, G. Getz, D. Mani, Pei Wang, F. Chen, G. Hostetter, M. Thiagarajan, W. Linehan, D. Fenyö, S. Jewell, G. Omenn, R. Mehra, M. Wiznerowicz, A. Robles, M. Mesri, Tara Hiltke, E. An, Henry Rodriguez, Daniel W. Chan, C. Ricketts, A. Nesvizhskii, Hui Zhang, Li Ding, Alicia Francis, A. Paulovich, A. Antczak, Anthony Green, A. Colaprico, A. Hakimi, B. Pruetz, B. Hindenach, B. Yadav, B. Reva, Brenda Fevrier-Sullivan, B. Druker, C. Szczylik, C. A. Goldthwaite, Chet Birger, Corbin D. Jones, D. Rohrer, Darlene Tansil, D. Chesla, David I Heiman, Elizabeth Duffy, Erin Schadt, F. Petralia, G. Bromiński, G. Quiroga-Garza, G. Wilson, Ginny X. Li, Grace Zhao, Y. Hsiao, J. Hsieh, J. Lubiński, Jasmin Bavarva, Jasmine Huang, J. Hafron, J. Eschbacher, Jennifer Hon, Jesse Francis, J. Freymann, Josh N. Vo, Joshua M Wang, J. Kirby, Kakhaber Zaalishvili, K. Ketchum, K. Hoadley, K. S. Um, L. Qi, M. Domagalski, Matt Tobin, Maureen A. Dyer, M. Anurag, M. Borucki, Michael A. Gillette, M. Birrer, M. Ittmann, M. Roehrl, M. Schnaubelt, Michael V. Smith, M. Fam, Nancy V. Roche, Negin Vatanian, Nicollette Maunganidze, O. Potapova, O. Paklina, Pamela VanderKolk, Patricia D. Castro, Paweł Kurzawa, P. Hariharan, Qin Li, Q. K. Li, R. Dhir, Ratna R. Thangudu, Rebecca Montgomery, Richard D. Smith, S. Mareedu, S. Payne, Sandra R. Cerda, S. Cottingham, Sarah Haynes, S. Satpathy, Shannon Richey, Shilpi Singh, S. Tsang, Shuang Cai, Song Cao, S. Gabriel, Steve Carr, T. Liu, Thomas Bauer, Toan Le, X. S. Chen, Xu Zhang, Y. Shutack, Zhen Zhang   +160 more
semanticscholar   +1 more source

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

medRxiv, 2021
Antigen recognition and T-cell mediated cytotoxicity in clear-cell renal cell carcinoma (ccRCC) remains incompletely understood. To address this knowledge gap, we analysed 115 multiregion tumour samples collected from 15 treatment-naive patients pre- and
L. Au, E. Hatipoglu, M. Robert de Massy, K. Litchfield, G. Beattie, A. Rowan, Desiree Schnidrig, R. Thompson, F. Byrne, S. Horswell, N. Fotiadis, S. Hazell, D. Nicol, S. Shepherd, A. Fendler, R. Mason, L. Del Rosario, K. Edmonds, K. Lingard, S. Sarker, Mary Mangwende, E. Carlyle, J. Attig, K. Joshi, Imran Uddin, P. Becker, M. W. Sunderland, A. Akarca, I. Puccio, William W. Yang, T. Lund, Kim Dhillon, M. Vasquez, E. Ghorani, Hang Xu, Charlotte Spencer, J. López, A. Green, U. Mahadeva, E. Borg, M. Mitchison, D. Moore, I. Proctor, M. Falzon, L. Pickering, A. Furness, J. Reading, R. Salgado, T. Marafioti, M. Jamal-Hanjani, G. Kassiotis, B. Chain, J. Larkin, C. Swanton, S. Quezada, S. Turajlic, C. Abbosh, K. Shiu, J. Bridgewater, D. Hochhauser, Martin D. Forster, S. Lee, T. Ahmad, D. Papadatos-Pastos, S. Janes, P. van Loo, Katey S. S. Enfield, N. Mcgranahan, A. Huebner, S. Beck, Peter J. Parker, H. Walczak, T. Enver, R. Hynds, Ron Sinclair, Chi-wah Lok, Zoe Rhodes, D. Moore, R. Khiroya, G. Trevisan, P. Ellery, M. Linch, S. Brandner, C. Hiley, S. Veeriah, Maryam Razaq, H. Shaw, G. Attard, M. Akther, C. Naceur-Lombardelli, Lizi Manzano, M. Al-Bakir, S. Summan, N. Kanu, S. Ward, U. Asghar, E. Lim, F. Gishen, A. Tookman, P. Stone, C. Stirling, N. Hunter, Sarah Vaughan, L. Spain, Haixi Yan, B. Shum, N. Yousaf, S. Popat, O. Curtis, G. Stamp, A. Toncheva, E. Nye, Aida Murra, Justine Korteweg, D. Josephs, A. Chandra, J. Spicer, Ruby Stewart, Lara-Rose Iredale, T. Mackay, B. Deakin, D. Enting, S. Rudman, Sharmistha Ghosh, Lena Karapagniotou, E. Pintus, A. Tutt, S. Howlett, V. Michalarea, J. Brenton, C. Caldas, Rebecca Fitzgerald, M. Jimenez-Linan, E. Provenzano, A. Cluroe, G. Stewart, C. Watts, R. Gilbertson, U. McDermott, S. Tavaré, E. Beddowes, P. Roxburgh, A. Biankin, A. Chalmers, S. Fraser, K. Oien, A. Kidd, K. Blyth, M. Krebs, F. Blackhall, Y. Summers, C. Dive, R. Marais, F. Gomes, M. Carter, Joanne Dransfield, J. Le Quesne, D. Fennell, J. Shaw, B. Naidu, S. Baijal, B. Tanchel, G. Langman, Andrew Robinson, M. Collard, P. Cockcroft, C. Ferris, H. Bancroft, A. Kerr, G. Middleton, J. Webb, S. Kadiri, P. Colloby, B. Olisemeke, Rodelaine Wilson, I. Tomlinson, S. Jogai, C. Ottensmeier, David Harrison, M. Loda, A. Flanagan, Mairead McKenzie, A. Hackshaw, J. Ledermann, Kitty Chan, A. Sharp, L. Farrelly, Hayley Bridger, B. Challacombe, S. Chowdhury, W. Drake, A. Fernando, K. Harrison-Phipps, Peter Hill, C. Horsfield, T. O'brien, J. Olsburgh, A. Polson, M. Varia, H. Verma   +199 more
semanticscholar   +1 more source

Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT

Diagnostic and Interventional Radiology, 2013
PURPOSEConventional clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma (pRCC) have different behavioral characteristics and clinical management strategies (nephrectomy vs. nephron-sparing surgery).
Pal Bata, Janos Gyebnar, David Laszlo Tarnoki, Adam Domonkos Tarnoki, Dora Kekesi, Attila Szendroi, Bence Fejer, A. Marcell Szasz, Peter Nyirady, Kinga Karlinger, Viktor Berczi   +10 more
doaj   +1 more source

Overexpression of TRIM2 suppresses proliferation, migration and stemness of clear cell renal cell carcinoma cells in vitro

Di-san junyi daxue xuebao, 2019
Objective To explore the effect of tripartite motif-containing protein 2 (TRIM2) on the proliferation, migration and stemness of clear cell renal clear carcinoma.
LUO Xing, LUO Jing, LIU Xin, ZHOU Tao, SUN Bishao   +4 more
doaj   +1 more source