, 2011 Effective lubrication performance of metal-on-metal hip implants only requires optimum conformity within the main loaded area, while it is advantageous to increase the clearance in the equatorial region.
Anissian H.L. +20 more
core +1 more source
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Shear joint capability versus bolt clearance [PDF]
The results of a conservative analysis approach into the determination of shear joint strength capability for typical space-flight hardware as a function of the bolt-hole clearance specified in the design are presented. These joints are comprised of high-
Lee, H. M.
core +1 more source
Dynamic Analysis of the Mechanism with Joint Clearance [PDF]
, 2015 随着工业水平的不断发展，含间隙机构的动力学及其控制的研究逐渐成为了一个热门课题。由于间隙的存在对机械机构的动力学特性造成了一定的影响，所以分析运动副间隙的影响对于机械机构设计和优化的意义就显得十分重大。本文中主要是以具有代表性的含间隙曲柄滑块机构和机械手臂机构为例，来分析间隙以及柔性因素给机械机构动力学特性带来的一些影响。 建立了机械系统的动力学方程，为含间隙机构动力学分析研究提供了理论基础；分析了基于弹簧阻尼模型的Impact接触碰撞函数，为研究轴与轴套间的接触碰撞过程提供了理论依据 ...
牟佳冬
core
Analysis of collocated feedback controllers for four-bar planar mechanisms with joint clearances [PDF]
, 2016 International audienceThis article presents an analysis of two-dimensional four-bar mechanisms with joint clearance, when one joint is actuated by collocated open-loop or state feedback controllers (proportional-derivative, state feedback linearization ...
Acary, Vincent +2 more
core +3 more sources
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats [PDF]
, 2017 The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in ...
Beaudry, F +6 more
core +3 more sources
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Dynamics Simulation and Experiment of the Slider-crank Mechanism with Dry Friction Clearance Joint
Jixie chuandong, 2017 Based on dynamics simulation software,the dynamics analysis of the slider-crank mechanism with clearance joint is carried out and the effect of joint with different clearance size under dry contact and non-friction conditions on dynamic response of ...
Han Yuncheng, Xu Lixin, Huang Xiaoqiu
doaj
Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt +8 more
wiley +1 more source