Results 81 to 90 of about 309,052 (305)
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Dynamics Simulation and Experiment of the Slider-crank Mechanism with Dry Friction Clearance Joint
Jixie chuandong, 2017 Based on dynamics simulation software,the dynamics analysis of the slider-crank mechanism with clearance joint is carried out and the effect of joint with different clearance size under dry contact and non-friction conditions on dynamic response of ...
Han Yuncheng, Xu Lixin, Huang Xiaoqiu
doaj
Dynamic Analysis of the Mechanism with Joint Clearance [PDF]
, 2015 随着工业水平的不断发展，含间隙机构的动力学及其控制的研究逐渐成为了一个热门课题。由于间隙的存在对机械机构的动力学特性造成了一定的影响，所以分析运动副间隙的影响对于机械机构设计和优化的意义就显得十分重大。本文中主要是以具有代表性的含间隙曲柄滑块机构和机械手臂机构为例，来分析间隙以及柔性因素给机械机构动力学特性带来的一些影响。 建立了机械系统的动力学方程，为含间隙机构动力学分析研究提供了理论基础；分析了基于弹簧阻尼模型的Impact接触碰撞函数，为研究轴与轴套间的接触碰撞过程提供了理论依据 ...
牟佳冬
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Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Jixie chuandong, 2001 This paper takes account of the boundary condition of elements of a joint with clearance when contact occur, by using the nonlinear spring damper formulation to model the resulting reaction force between the elements of clearance joint.
王国庆, 刘宏昭
doaj
Dynamics Behavior Analysis of Parallel Mechanism with Joint Clearance and Flexible Links
Shock and Vibration, 2018 In this study, the dynamics behaviors analysis of parallel mechanism considering joint clearance and flexible links are investigated using a computational methodology.
Chen Xiulong +3 more
doaj +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Identifying Trippers and Non-Trippers Based on Knee Kinematics During Obstacle-Free Walking [PDF]
, 2018 Trips are a major cause of falls. Sagittal-plane kinematics affect clearance between the foot and obstacles, however, it is unclear which kinematic measures during obstacle-free walking are associated with avoiding a trip when encountering an obstacle ...
Benson, Lauren C. +5 more
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Leakage performance of a novel turbomachinery shaft seal [PDF]
, 2009 Advanced sealing systems are needed to control parasitic leakage flows to achieve high turbine engine efficiency and low emissions. Typical extreme turbomachinery engine operating conditions when combined rotor excursions do not lend simple sealing ...
Akcan, Caner +3 more
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