Results 101 to 110 of about 328,516 (352)
Diels‐Alder clicks chemistry addresses thermal runaway in lithium‐ion batteries. A thermoresponsive electrolyte with lithium salt in vinylene carbonate (VC) and 2,5‐dimethylfuran (DMFu) operates at room temperature but undergoes Diels‐Alder reactions at high temperatures, enabling a two‐step safety mechanism: a warning phase at ≈100 °C and complete ...
Arnab Ghosh+9 more
wiley +1 more source
Application of Click Chemistry for PET [PDF]
Sharpless et al. presented, in 2001, a review in which they introduced the concept of "click chemistry". In this review a "new way" of making chemicals, with a particular emphasis on drugs, is presented. Current drugs are often based on natural products that were first extracted from plants or other organisms and then with enormous effort were ...
Bernard Feringa+4 more
openaire +4 more sources
Simultaneous utilization of calix[4]pyrrole‐ and crown ether‐based molecular recognition allows the construction of a high molecular weight alternating supramolecular polymer. This heat processible polymer can be used as a durable and reusable adhesive on glass and steel with temperature‐enhanced adhesion strength without the need for a solvent ...
Deniz Memis, Abdullah Aydogan
wiley +1 more source
La click-chemistry en el descubrimiento de fármacos [PDF]
La revisión bibliográfica que se presenta a continuación trata sobre la llamada clickchemistry y su aplicación en el descubrimiento de fármacos. Para ello se parte de la definición de click-chemistry y sus principales características que la hacen ...
González Vázquez, María
core
Design of On-Target FAAH Inhibitors [PDF]
In this issue of Chemistry & Biology, Alexander and Cravatt [1] propose a model for the binding of carbamate inhibitors to fatty acid amide hydrolase (FAAH), the enzyme that breaks down signaling lipids. Using competitive activity-based protein profiling
Deutsch, Dale G.
core +1 more source
Click reactions in chitosan chemistry [PDF]
The review provides the first generalized and systematized information on the use of click reactions in chitosan chemistry for the preparation of novel polymers with attractive physicochemical and biological properties. The reactions of copper-catalyzed azide—alkyne cycloaddition and the click reactions of chitosan derivatives occurring in the absence ...
Kritchenkov A.S., Skorik Y.A.
openaire +3 more sources
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia+7 more
wiley +1 more source
Syntheses of Sulfo-Glycodendrimers Using Click Chemistry and Their Biological Evaluation
A series of novel glycol-clusters containing sulfonated N-acetyl-D-glucosamine (GlcNAc) have been synthesized using click chemistry. Three dendrimers with aromatic dendrons were synthesized using chlorination, azidation and click chemistries.
Tomohiro Fukuda+2 more
doaj +1 more source
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman+6 more
wiley +1 more source
Metal free click chemistry on nucleosides and oligonucleotides [PDF]
Chemoselective ligation of biologically significant moieties through azide alkyne Click Chemistry has recently received much attention1. The reaction is attractive in that it regioselectively affords stable triazole linked bioconjugated products under ...
Batchelor, Caroline+3 more
core +1 more source