Results 111 to 120 of about 328,516 (352)
You Must Have Clicked on this Ad by Mistake! Data-Driven Identification of Accidental Clicks on Mobile Ads with Applications to Advertiser Cost Discounting and Click-Through Rate Prediction [PDF]
, 2018 In the cost per click (CPC) pricing model, an advertiser pays an ad network only when a user clicks on an ad; in turn, the ad network gives a share of that revenue to the publisher where the ad was impressed. Still, advertisers may be unsatisfied with ad networks charging them for "valueless" clicks, or so-called accidental clicks.
arxiv +1 more source
Advanced Healthcare Materials, EarlyView.Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre +5 more
wiley +1 more source
Alkyne-Azide “Click” Chemistry in Designing Nanocarriers for Applications in Biology
Molecules, 2013 The alkyne-azide cycloaddition, popularly known as the “click” reaction, has been extensively exploited in molecule/macromolecule build-up, and has offered tremendous potential in the design of nanomaterials for applications in a diverse range of ...
Pramod K. Avti +2 more
doaj +1 more source
Fluorophore-Assisted Click Chemistry through Copper(I) Complexation
Biomolecules, 2020 The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure efficient
Victor Flon +5 more
doaj +1 more source
Submicrometric Films of Surface-Attached Polymer Network with Temperature-Responsive Properties [PDF]
, 2016 Temperature-responsive properties of surface-attached poly(N-isopropylacrylamide) (PNIPAM) network films with well-controlled chemistry are investigated. The synthesis consists of cross-linking and grafting preformed ene-reactive polymer chains through thiol--ene click chemistry.
arxiv +1 more source
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Advanced Healthcare Materials, EarlyView.Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou +4 more
wiley +1 more source
Visible and selective gel assembly via covalent click chemistry
SmartMatThis study marks the birth of visible and selective click covalent assembly. It is achieved by amplifying orthogonal alkyne−azide click chemistry through interfacial multisite interactions between azide/alkyne functionalized polymer hydrogels ...
Yinglin Zheng, Zhihai Ke
doaj +1 more source
Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis
Advanced Healthcare Materials, EarlyView.An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back +3 more
wiley +1 more source
Click chemistry within LDPE [PDF]
, 2018 Specialty LDPE copolymers provide some of the highest added value polyolefin applications and, in the quest to differentiate in an increasingly commoditized polyolefin environment, are of considerable interest to LDPE producers and other polyolefin ...
Busch, Markus +4 more
core +1 more source
Layer-by-layer deposition of functional click polymers for microarray applications
eXPRESS Polymer Letters, 2019 Bioprobes immobilization methods that elevate the probes from the substrate are generally preferred in microarray technology because they prevent steric limitations during the hybridization of the target to probes.
L. Sola +8 more
doaj +1 more source