Results 141 to 150 of about 328,516 (352)

Combination of ring-opening polymerization and “click” chemistry towards functionalization of aliphatic polyesters [PDF]

, 2005
Raphaël Riva, Stéphanie Schmeits, François Stoffelbach, Christine Jérôme, Robert Jérôme, Philippe Lecomte   +5 more
openalex   +1 more source

Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide‐Based Binding Domains to Tailor Affinity

Advanced Materials Interfaces, EarlyView.
The 7‐mer peptide motifs QFFLFFQ, QFFEFFQ, and QFQQSFF, known as good, medium, and poor binders for the photosensitizers m‐THPC and Chlorin E6 are covalently immobilized on commercial amino‐functionalized silica particles by inverse electron‐demand Diels‐Alder ligation.
Steffen A. Busche, Lukas D. Bangert, Raoul D. Brand, Tommy Kröger, Enrico Heyl, Hans G. Börner   +5 more
wiley   +1 more source

SYNTHESIS AND CHARACTERISATION OF NOVEL BIOPOLYMERS VIA CLICK CHEMISTRY [PDF]

, 2011
The work throughout is the exploitation of copper catalysed Huisgen 1,3-dipolar azide–alkyne cycloaddition, as an efficient Click reaction, for the synthesis of novel biopolymers with a broad range of potential medical/industrial applications.
EISSA-MOHAMED, AHMED,MOHAMED
core  

Clicktok: Click Fraud Detection using Traffic Analysis [PDF]

arXiv, 2019
Advertising is a primary means for revenue generation for millions of websites and smartphone apps (publishers). Naturally, a fraction of publishers abuse the ad-network to systematically defraud advertisers of their money. Defenses have matured to overcome some forms of click fraud but are inadequate against the threat of organic click fraud attacks ...
arxiv  

Aqueous Synthesis of Poly(ethylene glycol)‐Amide‐Norbornene‐Carboxylate for Modular Hydrogel Crosslinking

Advanced Materials Interfaces, EarlyView.
An all aqueous synthesis of poly(ethylene glycol)‐amide‐norbornene‐carboxylate (PEGaNBCA) is developed via reacting carbic anhydride with amino‐terminated PEG. PEGaNBCA is readily crosslinked into hydrogels by click chemistries. PEGaNBCA crosslinked thiol‐norbornene hydrogels are hydrolytically stable but can be rendered hydrolytically labile through ...
Nathan H. Dimmitt, Chien‐Chi Lin
wiley   +1 more source

A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry

International Journal of Pharmaceutics: X, 2019
Targeted delivery of therapeutics is an attractive strategy for vascular diseases. Recently, variable domains of heavy-chain-only antibodies (VHHs) have gained momentum as targeting ligands to achieve this.
Marc V.A. van Moorsel, Rolf T. Urbanus, S. Verhoef, C.A. Koekman, Maurice Vink, T. Vermonden, Coen Maas, Gerard Pasterkamp, Raymond M. Schiffelers   +8 more
doaj  

“Clickphine”: A Novel and Highly Versatile P,N Ligand Class via Click Chemistry [PDF]

, 2006
Remko J. Detz, S. Arévalo Heras, R. De Gelder, Piet W. N. M. van Leeuwen, Henk Hiemstra, Joost N. H. Reek, Jan H. van Maarseveen   +6 more
openalex   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Antifouling PEG Coatings by Thiol‐Acrylate Conjugate Addition Reactions for Generation of Protein Patterns via Photobleaching‐Induced Protein Binding (PiPB) BioBitmaps Using Maskless Projection Lithography

Advanced Materials Interfaces, EarlyView.
Homo‐bifunctional PEG, acrylate‐PEG‐acrylate (PEGDA), coatings are prepared on glass and glass‐type surfaces using solvent‐free thiol‐acrylate conjugate addition reactions at room temperature. The prepared PEGDA coatings are stable, antifouling, and provide feature terminal acrylates that can act as free radical acceptors for photobleaching‐induced ...
Ali Usama, Evelin Schäfer, Pang Zhu, Qingchuan Song, Alexander Weißbach, Dorothea Helmer, Joachim Wollschläger, Changjiang You, Martin Steinhart, Pegah Pezeshkpour, Peilong Hou, Bastian E. Rapp   +11 more
wiley   +1 more source

Click chemistry in the development of PROTACs

RSC Chemical Biology
This review discusses leveraging click chemistry to address unmet needs in PROTAC development.
Ce Yang, Ravi Tripathi, Binghe Wang
openaire   +2 more sources