Results 201 to 210 of about 328,516 (352)

Convenient Approach to Access Octa-Glycosylated Porphyrins via “Click Chemistry” [PDF]

, 2009
Misako Okada, Yuko Kishibe, Kanako Ide, T. Takahashi, Teruaki Hasegawa   +4 more
openalex   +1 more source

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1‐NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang, Jiazhuang Zhu, Jianping Hu, Xingkai Wang, Xiaolong Ma, Enjie Xu, Kunpeng Zhu, Chunlin Zhang   +7 more
wiley   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source

Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using ‘click chemistry’

, 2008
Farnusch Kaschani, Steven H. L. Verhelst, Paul F. van Swieten, Martijn Verdoes, C.‐H. Wong, Zhe-Ming Wang, Markus Kaiser, Herman S. Overkleeft, Matthew Bogyo, Renier A. L. van der Hoorn   +9 more
openalex   +1 more source

Polymer Multilayer Films Obtained by Electrochemically Catalyzed Click Chemistry [PDF]

, 2009
Gaulthier Rydzek, Jean‐Sébastien Thomann, Nejla Ben Ameur, Loı̈c Jierry, Philippe J. Mésini, Arnaud Ponche, Christophe Contal, Alae El Haitami, Jean‐Claude Voegel, Bernard Senger, Pierre Schaaf, Benoı̂t Frisch, Fouzia Boulmedais   +12 more
openalex   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Combinatorial and Automated Synthesis of Phosphodiester Galactosyl Cluster on Solid Support by Click Chemistry Assisted by Microwaves

, 2008
Gwladys Pourceau, Albert Meyer, Jean‐Jacques Vasseur, F. Morvan   +3 more
openalex   +1 more source

Synthesis of Red-Shifted 8-Hydroxyquinoline Derivatives Using Click Chemistry and Their Incorporation into Phosphorylation Chemosensors [PDF]

, 2009
Juan A. González‐Vera, Elvedin Luković, Barbara Imperiali   +2 more
openalex   +1 more source

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

Advanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou, Chao Dong, Xiaochun Shen, Pengbo Wang, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Chengxiang Xu, Kaipeng Duan, Dongbao Li, Jin Zhou   +11 more
wiley   +1 more source

Signature of click chemistry in advanced techniques for cancer therapeutics. [PDF]

RSC Adv
Ragab SS.
europepmc   +1 more source