Results 231 to 240 of about 3,191,477 (292)

Bio-orthogonal functionalization of bacterial cellulose combining metabolic glycoengineering and click chemistry. [PDF]

Nat Commun
Chen S, Tang H, Fan X, Li B, Wang Y, Zhou W, Jiang X, Dong X, Wang Y, Zhao P, Ye T, An B, Zheng Y, Zhong C.   +13 more
europepmc   +1 more source

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

Advanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser, Haseeb Muhammad, Junaid Younas, Gillian Lovell, Bianca Migliori, Andreas Dengel, Sheraz Ahmed   +6 more
wiley   +1 more source

Click Chemistry-Based Strategy for Modular Ligand Attachment to siRNAs: Toward Extrahepatic RNAi

Rädler JA, Filipiak E, Marquant A, Ojansivu M, Czapik T, Hill A, Ahlskog N, Roudi S, Barradas C, Huang Y, Saher O, Wood M, Zain R, Honcharenko M, EL Andaloussi S.   +14 more
europepmc   +1 more source

Versatility of Click Chemistry in Hydrogel Synthesis: From Molecular Strategies to Applications in Regenerative Medicine. [PDF]

Gels
Carrascal-Hernández DC, Grande-Tovar CD, Insuasty D, Márquez E, Mendez-Lopez M.   +4 more
europepmc   +1 more source

Printed Wearable Sweat Rate Sensor for Continuous In Situ Perspiration Measurement

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A wireless wearable sweat rate sensor system is presented, featuring digital 3D direct‐write printing on a flexible substrate with microfluidic layers for continuous, real‐time monitoring. Printed encapsulated metal electrodes are used for capacitance measurements, achieving high sensitivity (0.01 μL min−1) while maintaining a compact and lightweight ...
Mohammad Shafiqul Islam, Sangwon Cha, Md Farhad Hassan, Wenxin Cai, Tahsin Sejat Saniat, Cedar Rose Leach, Yasser Khan   +6 more
wiley   +1 more source

Applying click chemistry principles to the design of tumor-targeted nanosystems. [PDF]

Nanomedicine (Lond)
Diaz-Mochon JJ, Sanchez-Martin RM.
europepmc   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Click chemistry of phenyl 1,2,3-triazole-2-pyridylpiperazine hybrids: synthesis, targeted anticancer activity, molecular modeling and computational studies. [PDF]

RSC Adv
El Malah T, El-Rashedy AA.
europepmc   +1 more source

pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging

Advanced NanoBiomed Research, EarlyView.
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang, Liwei Liu, Jiayuan Zhu, Xinghao Hu, Changkui Fu, Yao Wang, Lining Arnold Ju, Thomas P. Davis, Andriansjah Rukmana, Shaohua Ma, Zheng Zhang, Ruirui Qiao   +11 more
wiley   +1 more source

Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives. [PDF]

Molecules
Beeser L, Armstrong D, Fullerton MS, Beasley I, Treadway W, Nikkel C, Ho ML, Glenn B, Mills C, Budhathoki S, Parchman J, Holdiness R, Smith J, Hodge Z, Dragan AL, Alam MA, Shields RC, Voth DE, Nawarathne IN.   +18 more
europepmc   +1 more source