Results 21 to 30 of about 319,759 (300)
Click-Chemistry-Assisted Alteration of Glycosaminoglycans for Biological Applications
SynOpen, 2023 This short review describes the assistance of click chemistry in the chemical modification of glycosaminoglycans. Through an alkyne-azide 1,3-dipolar cycloaddition reaction, the chemically and physiologically stable triazole unit connects ...
Smritilekha Bera, Dhananjoy Mondal
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Applications of Click Chemistry in Radiopharmaceutical Development
CHIMIA, 2010 Click chemistry, a concept that employs only practical and reliable transformations for compound synthesis, has made a significant impact in several areas of chemistry, including material sciences and drug discovery.
Joseph C. Walsh, Hartmuth C. Kolb
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Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1 [PDF]
, 2011 We describe the use of iterative in situ click chemistry to design an Akt-specific branched peptide triligand that is a drop-in replacement for monoclonal antibodies in multiple biochemical assays.
Agnew, Heather D. +12 more
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Click Chemistry in Materials Science [PDF]
, 2014 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106803/1/adfm201302847 ...
Bowman, Christopher N. +3 more
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Click Chemistry in Human Cancer Research
Zhongliu Fangzhi YanjiuAs one of the typical bioorthogonal chemistry reactions, click chemistry joins molecules similar to “Lego”. Bioorthogonal click chemistry is used to modify cancer cells, design antitumor drugs, delivery drugs, manipulate immune cells, and help ...
Baihong ZHANG, Hongyun YUE
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Triazolinediones as highly enabling synthetic tools [PDF]
, 2016 Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation.
Billiet, Stijn +5 more
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Click chemistry in carbon nanoreactors [PDF]
Chemical Communications, 2013 Copper-nanoparticle catalytic centres anchored at the graphitic step-edges within hollow carbon nanoreactors exhibit superior activity and stability in cycloaddition reactions as compared to catalytic centres outside the nanoreactors. Nanoscale confinement enables efficient recycling of the catalyst in preparative-scale synthesis without significant ...
Rance, Graham A. +2 more
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Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry [PDF]
, 2013 Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the
Anna Lucia Fallacara +11 more
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Layer-by-layer biofabrication of coronary covered stents with clickable elastin-like recombinamers [PDF]
, 2019 Producción CientíficaCoronary artery disease is the leading cause of death around the world. Endovascular stenting is the preferred treatment option to restore blood flow in the coronary arteries due to the lower perioperative morbidity when compared ...
Fernández Colino, Alicia +7 more
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Click-Chemistry Cross-Linking of Hyaluronan Graft Copolymers
Pharmaceutics, 2022 An easy and viable crosslinking procedure by click-chemistry (click-crosslinking) of hyaluronic acid (HA) was developed. In particular, the clickable propargyl groups of hyaluronane-based HA-FA-Pg graft copolymers showing low and medium molecular weight ...
Mario Saletti +12 more
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