Results 11 to 20 of about 319,759 (300)

Click chemistry with DNA [PDF]

Chemical Society Reviews, 2010
The advent of click chemistry has led to an influx of new ideas in the nucleic acids field. The copper catalysed alkyne-azide cycloaddition (CuAAC) reaction is the method of choice for DNA click chemistry due to its remarkable efficiency. It has been used to label oligonucleotides with fluorescent dyes, sugars, peptides and other reporter groups, to ...
El-Sagheer, Afaf H., Brown, Tom
openaire   +7 more sources

Intercalation Engineering of 2D Materials at Macroscale for Smart Human–Machine Interface and Double‐Layer to Faradaic Charge Storage for Ions Separation

Advanced Materials Interfaces, 2023
2D materials have attracted considerable attention in the past decade for their superlative physical properties. Lightweight foam from 2D materials can reduce the use of raw materials, save energy in processing the material and downregulate the carbon ...
Rahul Patil, Saikat Dutta
doaj   +1 more source

Enhanced protein–protein interaction network construction promoted by in vivo cross-linking with acid-cleavable click-chemistry enrichment

Frontiers in Chemistry, 2022
Chemical cross-linking coupled with mass spectrometry has emerged as a powerful strategy which enables global profiling of protein interactome with direct interaction interfaces in complex biological systems.
Lili Zhao, Lili Zhao, Bowen Zhong, Yuxin An, Yuxin An, Weijie Zhang, Weijie Zhang, Hang Gao, Hang Gao, Xiaodan Zhang, Zhen Liang, Yukui Zhang, Qun Zhao, Lihua Zhang   +13 more
doaj   +1 more source

Click Chemistry with Cyclopentadiene

Chemical Reviews, 2021
Cyclopentadiene is one of the most reactive dienes in normal electron-demand Diels-Alder reactions. The high reactivities and yields of cyclopentadiene cycloadditions make them ideal as click reactions. In this review, we discuss the history of the cyclopentadiene cycloaddition as well as applications of cyclopentadiene click reactions. Our emphasis is
Brian J. Levandowski, Ronald T. Raines
openaire   +3 more sources

Recent Advancements in Triazole-based Click Chemistry in Cancer Drug Discovery and Development

SynOpen, 2023
Triazole-based compounds possess a broad range of activity and can be synthesized using click chemistry. Many new chemotherapeutic agents have been developed in recent years by exploiting click chemistry and these are covered in this review.
Arun Kumar, Ashok Kumar Yadav, Vivek Mishra, Deepak Kumar   +3 more
doaj   +1 more source

Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Click chemistry reactions constitute an important and relatively new approach in the medicinal chemistry toolbox and offer substantial advantages to medicinal chemists in terms of overcoming the limitations of facile chemical synthesis, increased ...
Andrea Angeli, Claudiu T. Supuran
doaj   +1 more source

Application of click chemistry in nanoparticle modification and its targeted delivery

Biomaterials Research, 2018
Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi, Jihwan Son, Jihye Yoo, Changhee Park, Heebeom Koo   +4 more
doaj   +1 more source

Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]

, 2013
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa, Gopalan, Began, Hauser, Charlotte A. E., Joshi, Mangesh, Lakshmanan, Anupama, Lam, Dang Hoang, Mishra, Archana, Reithofer, Michael R., Wang, Shu   +8 more
core   +1 more source

Bio-click chemistry: a bridge between biocatalysis and click chemistry

RSC Advances, 2022
This review summarizes chemo/biocatalytic syntheses that combine the highly efficient click chemistry reactions with the advantages of biocatalysis. The concept of bio-click chemistry and its implications are introduced in this review.
Diego F. Rodríguez, Yanina Moglie, César A. Ramírez-Sarmiento, Sachin Kumar Singh, Kamal Dua, Flavia C. Zacconi   +5 more
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Nanoplasmonics tuned “click chemistry” [PDF]

Nanoscale, 2016
Nanoplasmonics is a growing field of optical condensed matter science dedicated to optical phenomena at the nanoscale level in metal systems. Extensive research on noble metallic nanoparticles (NPs) has emerged within the last two decades due to their ability to keep the optical energy concentrated in the vicinity of NPs, in particular, the ability to ...
Tijunelyte, I., Guenin, E., Lidgi-guigui, N., Colas, Florent, Ibrahim, J., Toury, T., Lamy De La Chapelle, M.   +6 more
openaire   +3 more sources