Results 11 to 20 of about 2,703,843 (291)

Click chemistry with DNA [PDF]

open access: yesChemical Society Reviews, 2010
The advent of click chemistry has led to an influx of new ideas in the nucleic acids field. The copper catalysed alkyne-azide cycloaddition (CuAAC) reaction is the method of choice for DNA click chemistry due to its remarkable efficiency. It has been used to label oligonucleotides with fluorescent dyes, sugars, peptides and other reporter groups, to ...
El-Sagheer, Afaf H., Brown, Tom
openaire   +6 more sources

Recent Advances in Click Chemistry Applied to Dendrimer Synthesis

open access: yesMolecules, 2015
Dendrimers are monodisperse polymers grown in a fractal manner from a central point. They are poised to become the cornerstone of nanoscale devices in several fields, ranging from biomedicine to light-harvesting. Technical difficulties in obtaining these
Mathieu Arseneault   +2 more
doaj   +2 more sources

Organotitanium Click Chemistry [PDF]

open access: yes, 2023
The click chemistry of titanium exemplified by the “green” [3+2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising ...
Gregory, Arzoumanidis
core   +1 more source

Click to learn, learn to click: Undergraduate Synthetic Organic Chemistry experiments [PDF]

open access: yes, 2022
The optimization of an undergraduate experiment for Organic Chemistry students is described to explore the concept of click chemistry. The preparation of a terminal fluorescent alkyne and an organic azide is reported consisting of simple steps. These are
Francisco, Santoyo-Gonzalez   +3 more
core   +2 more sources

Unfolding Potential of Click Chemistry in Bioconjugation: A Review [PDF]

open access: yes, 2023
The application of click chemistry, specifically Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC), in bioconjugation has shown tremendous promise in various biomedical fields.
Fathima Shadin, P
core   +1 more source

Redox-Click Chemistry for Disulfide Formation from Thiols [PDF]

open access: yes, 2023
The dynamic disulfide linkage plays a vital role in various biological processes as well as drugs and biomaterials. Oxidation of thiols is a widely utilized approach for disulfide synthesis; however, achieving both optimal reactivity and selectivity ...
Xiaohe, Zhang   +19 more
core   +2 more sources

Accelerated SuFEx Click Chemistry for Modular Synthesis [PDF]

open access: yes, 2021
Click chemistry is a method for the rapid synthesis of functional molecules with desirable properties. We report the development of accelerated SuFEx, a powerful click reaction for the efficient coupling of aryl and alkyl alcohols directly with SuFExable
Timothy, Gialelis   +2 more
core   +3 more sources

Phosphorus(V) Fluoride Exchange (PFEx): Multidimensional Click Chemistry from Phosphorus(V) Connective Hubs [PDF]

open access: yes, 2022
We report catalytic Phosphorus Fluoride Exchange (PFEx) as the latest advance in connective click-reaction technology. Emulating Nature, PFEx reaches into the biological world and creates stable tetrahedral P(V)- connections through efficient phosphorus ...
Shoujun, Sun   +5 more
core   +2 more sources

Harnessing Sulfur(VI) Fluoride Exchange Click Chemistry and Photocatalysis for Deaminative Benzylic Arylation [PDF]

open access: yes, 2023
While among the most common functional handles present in organic molecules, amines are a widely underutilized linchpin for C–C bond formation. To facilitate C–N bond cleavage, large activating groups are typically used but result in the generation of ...
Akin, Aydogan   +5 more
core   +1 more source

Biocompatible nanoreactors of catalase and nanozymes for anticancer therapeutics

open access: yesNano Select, 2021
Significant progress has laid the groundwork in understanding the fundamental role of catalase enzyme and catalase‐like nanozymes, notably with the emergence of nano‐bioreactors which are promoting nanomaterials‐based antitumor therapeutic strategies ...
Tanya Munjal, Saikat Dutta
doaj   +1 more source

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