Results 11 to 20 of about 204,788 (255)

Biocompatible nanoreactors of catalase and nanozymes for anticancer therapeutics

open access: yesNano Select, 2021
Significant progress has laid the groundwork in understanding the fundamental role of catalase enzyme and catalase‐like nanozymes, notably with the emergence of nano‐bioreactors which are promoting nanomaterials‐based antitumor therapeutic strategies ...
Tanya Munjal, Saikat Dutta
doaj   +1 more source

Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications

open access: yesMolecules, 2021
The click azide = alkyne 1,3-dipolar cycloaddition (click chemistry) has become the approach of choice for bioconjugations in medicinal chemistry, providing facile reaction conditions amenable to both small and biological molecules.
Daniela Perrone   +3 more
doaj   +1 more source

Enhanced protein–protein interaction network construction promoted by in vivo cross-linking with acid-cleavable click-chemistry enrichment

open access: yesFrontiers in Chemistry, 2022
Chemical cross-linking coupled with mass spectrometry has emerged as a powerful strategy which enables global profiling of protein interactome with direct interaction interfaces in complex biological systems.
Lili Zhao   +13 more
doaj   +1 more source

Intercalation Engineering of 2D Materials at Macroscale for Smart Human–Machine Interface and Double‐Layer to Faradaic Charge Storage for Ions Separation

open access: yesAdvanced Materials Interfaces, 2023
2D materials have attracted considerable attention in the past decade for their superlative physical properties. Lightweight foam from 2D materials can reduce the use of raw materials, save energy in processing the material and downregulate the carbon ...
Rahul Patil, Saikat Dutta
doaj   +1 more source

Click triazole as a linker for drug repurposing against SARs-CoV-2: A greener approach in race to find COVID-19 therapeutic

open access: yesCurrent Research in Green and Sustainable Chemistry, 2021
WHO holding the hands of the scientific commune and trying to repurpose the drugs against the SARS-CoV-2. The robust scientific data has illustrated the probable mechanistic path of SARS-CoV-2 entry and action in damaging the cells.
Satyaki Chatterjee   +4 more
doaj   +1 more source

Recent Advancements in Triazole-based Click Chemistry in Cancer Drug Discovery and Development

open access: yesSynOpen, 2023
Triazole-based compounds possess a broad range of activity and can be synthesized using click chemistry. Many new chemotherapeutic agents have been developed in recent years by exploiting click chemistry and these are covered in this review.
Arun Kumar   +3 more
doaj   +1 more source

Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Click chemistry reactions constitute an important and relatively new approach in the medicinal chemistry toolbox and offer substantial advantages to medicinal chemists in terms of overcoming the limitations of facile chemical synthesis, increased ...
Andrea Angeli, Claudiu T. Supuran
doaj   +1 more source

Heterogeneous Photocatalytic Click Chemistry [PDF]

open access: yesJournal of the American Chemical Society, 2016
Copper-doped semiconductors are designed to photoassist the alkyne-azide cycloaddition catalysis by Cu(I). Upon irradiation, injection of electrons from the semiconductor into copper oxide nanostructures produces the catalytic Cu(I) species. The new catalysts are air- and moisture-tolerant and can be readily recovered after use and reused several times.
Wang, Bowen   +4 more
openaire   +3 more sources

Application of click chemistry in nanoparticle modification and its targeted delivery

open access: yesBiomaterials Research, 2018
Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi   +4 more
doaj   +1 more source

Click chemistry in carbon nanoreactors [PDF]

open access: yesChemical Communications, 2013
Copper-nanoparticle catalytic centres anchored at the graphitic step-edges within hollow carbon nanoreactors exhibit superior activity and stability in cycloaddition reactions as compared to catalytic centres outside the nanoreactors. Nanoscale confinement enables efficient recycling of the catalyst in preparative-scale synthesis without significant ...
Rance, Graham A.   +2 more
openaire   +2 more sources

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