Results 51 to 60 of about 327,716 (251)
Comparative Analysis of Click Chemistry Mediated Activity-Based Protein Profiling in Cell Lysates
Molecules, 2013 Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group.
Yinliang Yang +2 more
doaj +1 more source
Click-based porous cationic polymers for enhanced carbon dioxide capture [PDF]
J. Mater. Chem. A, 2017,5, 372 to 383, 2017 Imidazolium based porous cationic polymers were synthesized using an innovative and facile approach, which takes advantage of the Debus Radziszewski reaction to obtain meso- and microporous polymers following click chemistry principles. In the obtained set of materials, click based porous cationic polymers have the same cationic backbone, whereas they ...
arxiv +1 more source
Recent Advances in Transition Metal-Catalyzed Ring-Opening Reaction of Aziridine
CompoundsThe smallest strained, saturated N-heterocycles, such as aziridine, can be a valuable building block in synthetic organic chemistry. Ring-opening reactions with various nucleophiles could be the most important strategy to synthesize various value-added ...
Partha Sarathi Bera +3 more
doaj +1 more source
Catalysis in Click Chemistry Reactions Controlled by Cavity Quantum Vacuum Fluctuations: The Case of endo/exo Diels-Alder Reaction [PDF]
arXiv, 2022 Achieving control over chemical reaction's rate and stereoselectivity realizes one of the Holy Grails in chemistry that can revolutionize chemical and pharmaceutical industries. Strong light-matter interaction in optical or nanoplasmonic cavities might provide the knob to reach such control.
arxiv
Additive manufacturing of ceramics from preceramic polymers: A versatile stereolithographic approach assisted by thiol-ene click chemistry [PDF]
Additive Manufacturing, 2019, Vol 27, 80-90, 2019 Here we introduce a versatile stereolithographic route to produce three different kinds of Si-containing thermosets that yield high performance ceramics upon thermal treatment. Our approach is based on a fast and inexpensive thiol-ene free radical addition that can be applied for different classes of preceramic polymers with carbon-carbon double bonds.
arxiv +1 more source
, 2019 Click chemistry has found wide application in bioconjugation, enabling control over the site of modification in biomolecules. Demonstrations of this chemistry to construct chemically defined antibody-drug conjugates (ADCs) have increased in recent years, following studies that support benefits of homogeneity and site-specificity of drug placement on ...
Tak Ian Chio, Susan Bane
openaire +4 more sources
Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry [PDF]
, 2013 Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the
Anna Lucia Fallacara +11 more
core +1 more source
Click Chemistry in Natural Product Modification
Frontiers in Chemistry, 2021 Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang +5 more
doaj +1 more source
Reaction profiles for quantum chemistry-computed [3 + 2] cycloaddition reactions [PDF]
arXiv, 2022 Bio-orthogonal click chemistry based on [3 + 2] dipolar cycloadditions has had a profound impact on the field of biochemistry and significant effort has been devoted to identify promising new candidate reactions for this purpose. To gauge whether a prospective reaction could be a suitable bio-orthogonal click reaction, information about both on- and ...
arxiv