Results 181 to 190 of about 2,796,861 (304)

Facile Synthesis of Sulfur-Containing Functionalized Disiloxanes with Nonconventional Fluorescence by Thiol-Epoxy Click Reaction. [PDF]

Int J Mol Sci, 2023
Tang J, Feng S, Wang D.
europepmc   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

Self-supplying hydrogen peroxide-driven gold nanoparticle aggregation via bio-orthogonal click reaction activates cGAS-STING-PERK pathway for multimodal tumor therapy. [PDF]

J Nanobiotechnology
Li J, Hu K, Lee ML, Li T, Chen P, Wang C, Li HW.   +6 more
europepmc   +1 more source

Thiol-ene click reaction as an effective tool for the synthesis of PEG-functionalized alkoxysilanes-precursors of anti-fog coatings. [PDF]

Sci Rep, 2023
Kaczmarek M, Przybylska A, Szymańska A, Dutkiewicz A, Maciejewski H.   +4 more
europepmc   +1 more source

AMPing up click reactions [PDF]

Nature Chemical Biology, 2011
openaire   +1 more source

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

Advanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu, Jingfan Wang, Pengfei Ge, Qinyuan Gu, Hongying Li, Yuanyuan Fan, Haiyue Xie, Yangyang Lu, Yifan Lin, Xinjing Wu, Chengkun Wang, Ping Xie, Zizhong Hu   +12 more
wiley   +1 more source

Efficient and rapid cell surface functionalization: a sub-minute selenol-yne click reaction for bioconjugation. [PDF]

Chem Sci
Shan F, Heng X, Yao L, Xu G, Hu J, Pan X, Chen G.   +6 more
europepmc   +1 more source

Ionizable Lipids with Triazole Moiety from Click Reaction for LNP-Based mRNA Delivery. [PDF]

Molecules, 2023
Wang Y, Si X, Feng Y, Feng D, Xu X, Zhang Y.   +5 more
europepmc   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

Copper immobilized MIL-125-NH₂ as an efficient nanocatalyst for click reaction and synthesis of benzo[b]pyrans. [PDF]

Sci Rep
Sadati Z, Alinezhad H, Tajbakhsh M.
europepmc   +1 more source