Results 271 to 280 of about 2,796,861 (304)

Radical-mediated click-clip reactions

Science
Click reactions, which are characterized by rapid, high-yielding, and highly selective coupling of two reaction partners, are powerful tools in synthesis but are rarely reversible. Innovative strategies that reverse such couplings in a precise and on-demand manner, enabling a click-clip sequence, would greatly expand the technique’s versatility. Herein,
Jiantao Zhao, Huacheng Yu, Xingchen Jin, Bo Qin, Shan Mei, Jiang-Fei Xu, Xi Zhang   +6 more
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Heterovalent Click Reactions on DNA Origami

Bioconjugate Chemistry
Nucleic acid nanoparticles (NANPs) fabricated by using the DNA origami method have broad utility in materials science and bioengineering. Their site-specific, heterovalent functionalization with secondary molecules such as proteins or fluorophores is a unique feature of this technology that drives its utility.
Grant A. Knappe, Jeffrey Gorman, Andrew N. Bigley, Steven P. Harvey, Mark Bathe   +4 more
openaire   +2 more sources

The potential of click reactions for the synthesis of bioactive triterpenes

Bioorganic & Medicinal Chemistry Letters, 2019
Click reactions between alkynes and azides using the privileged scaffold of triterpenes have been of interest for biological chemistry. Many publications deal with the synthesis of novel bioactive molecules; these conjugates have also been used for bioanalytical and diagnostic purposes.
Csuk, René, Deigner, Hans-Peter
openaire   +3 more sources

Core functionalization of polydiacetylene micelles by a “click” reaction

Soft Matter, 2011
Diacetylene amphiphile bearing terminal alkyne moiety form micelles which can be further photopolymerized. Herein we address the covalent grafting of a fluorescent label within the micelles by a “click” reaction. Fluorescence experiments revealed that micelles act for the label as a protective shield from the bulk water.
Contal, Emmanuel, Klymchenko, Andrey, Mély, Yves, Meunier, Stephane, Wagner, Alain   +4 more
openaire   +2 more sources

Horseradish‐Peroxidase‐Catalyzed Tyrosine Click Reaction

ChemBioChem, 2017
AbstractThe efficiency of protein chemical modification on tyrosine residues with N‐methylluminol derivatives was drastically improved by using horseradish peroxidase (HRP). In the previous method, based on the use of hemin and H2O2, oxidative side reactions such as cysteine oxidation were problematic for functionalization of proteins selectively on ...
Shinichi Sato, Kosuke Nakamura, Hiroyuki Nakamura   +2 more
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Surface immobilization of biomolecules by click sulfonamide reaction

Chemical Communications, 2008
Alkyne-modified biomolecules can be immobilized site- and chemoselectively on sulfonylazide slides under very mild conditions by means of the click sulfonamide reaction.
Govindaraju, T., Jonkheijm, P., Gogolin, L., Schroeder, H., Becker, C., Niemeyer, C., Waldmann, H.   +6 more
openaire   +3 more sources

Kinugasa Reaction under Click Chemistry Conditions

Synlett, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A. Basak, K. Chandra, R. Pal, S. C. Ghosh   +3 more
openaire   +1 more source

Polymer “Clicking” by CuAAC Reactions

Macromolecular Rapid Communications, 2008
AbstractThe CuAAC “click” reaction has developed as one of the most useful and widely employed reactions in ligation within polymer chemistry. This is due to the unique properties of the Cu(I) catalysis which renders the reaction quantitative even at low concentrations, orthogonal with other chemistries and extremely robust.
openaire   +1 more source

Miscellaneous Click and Click-like Reactions in Polymer Science

Click chemistry approaches have directed the materials research community to access a diverse range of complex polymeric systems. Click chemistry involves exploiting the easy-to-execute chemical reactions that can be performed at ambient conditions while being efficient and rapid.
Prantik Mondal, Nikhil K. Singha, Richard Hoogenboom   +2 more
openaire   +1 more source

Two-color emissive probes for click reactions

Chem. Commun., 2014
CuAAC is visualized using a BODIPY reaction system by the bathochromic shift of the fluorescence wavelength in ensemble and microscopy experiments. Reaction progress is correlated with chromophore elongation fading out disturbing background fluorescence.
Marcel, Wirtz, Andreas, Grüter, Philipp, Rebmann, Tobias, Dier, Dietrich A, Volmer, Volker, Huch, Gregor, Jung   +6 more
openaire   +2 more sources