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Current Organic Chemistry, 2016
The Diels-Alder reactions can be classified as click reactions because of their simplicity and high yields. The Diels-Alder click reactions have been used for the preparation of complex macromolecules, such as hydrogels and polymers and also for labeling of various biological targets.
Dajana Ga.so-Soka.c, Marija Stivojevi.c
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The Diels-Alder reactions can be classified as click reactions because of their simplicity and high yields. The Diels-Alder click reactions have been used for the preparation of complex macromolecules, such as hydrogels and polymers and also for labeling of various biological targets.
Dajana Ga.so-Soka.c, Marija Stivojevi.c
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Clusters for alkyne-azide click reactions
Dalton Transactions, 2010The clusters Ti(6)O(4)(OPr)(8)(OOC(CH(2))(2)C[triple bond]CH)(8) and [Zr(6)O(4)(OH)(4)(OOC(CH(2))(3)C[triple bond]CH)(12)](2) with acetylenic carboxylate ligands were prepared and structurally characterized in solution and in the crystalline state. Model reactions showed that they are suitable candidates for the formation of cluster-based inorganic ...
Philipp, Heinz +4 more
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Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction
Chemical Communications, 2007Horse spleen apoferritin, the hollow protein shell derived from ferritin, a special biological nanoparticle, can be chemoselectively modified at the lysine residues, which affords a robust scaffold for further chemical reactions including Cu(i)-catalyzed azide-alkyne cycloaddition reaction and atom transfer radical polymerization reaction.
Qingbing, Zeng +5 more
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Kinugasa Reaction under Click Chemistry Conditions
Synlett, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Subhash Chandra Ghosh
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Intramolecular Nitrone Interrupted Click Reaction
Organic LettersWe document the intramolecular interception of a Cu-catalyzed azidoalkyne cycloaddition employing a suitably placed nitrone group, providing a simple route to the unprecedented spiro-polyheterocyclic scaffold. The reaction is comprised of a Cu-catalyzed [3 + 2]-cycloaddition of (2-azidoaryl)isatogen with a terminal alkyne and the intramolecular ...
Tejas A. Pothi, Chepuri V. Ramana
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Radical-mediated click-clip reactions
ScienceClick reactions, which are characterized by rapid, high-yielding, and highly selective coupling of two reaction partners, are powerful tools in synthesis but are rarely reversible. Innovative strategies that reverse such couplings in a precise and on-demand manner, enabling a click-clip sequence, would greatly expand the technique’s versatility. Herein,
Jiantao Zhao +6 more
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Heterovalent Click Reactions on DNA Origami
Bioconjugate ChemistryNucleic acid nanoparticles (NANPs) fabricated by using the DNA origami method have broad utility in materials science and bioengineering. Their site-specific, heterovalent functionalization with secondary molecules such as proteins or fluorophores is a unique feature of this technology that drives its utility.
Grant A. Knappe +4 more
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The potential of click reactions for the synthesis of bioactive triterpenes
Bioorganic & Medicinal Chemistry Letters, 2019Click reactions between alkynes and azides using the privileged scaffold of triterpenes have been of interest for biological chemistry. Many publications deal with the synthesis of novel bioactive molecules; these conjugates have also been used for bioanalytical and diagnostic purposes.
Csuk, René, Deigner, Hans-Peter
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Core functionalization of polydiacetylene micelles by a “click” reaction
Soft Matter, 2011Diacetylene amphiphile bearing terminal alkyne moiety form micelles which can be further photopolymerized. Herein we address the covalent grafting of a fluorescent label within the micelles by a “click” reaction. Fluorescence experiments revealed that micelles act for the label as a protective shield from the bulk water.
Contal, Emmanuel +4 more
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Horseradish‐Peroxidase‐Catalyzed Tyrosine Click Reaction
ChemBioChem, 2017AbstractThe efficiency of protein chemical modification on tyrosine residues with N‐methylluminol derivatives was drastically improved by using horseradish peroxidase (HRP). In the previous method, based on the use of hemin and H2O2, oxidative side reactions such as cysteine oxidation were problematic for functionalization of proteins selectively on ...
Shinichi Sato +2 more
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