Results 261 to 270 of about 597,976 (301)

Click Reactions with Nitroxides

Synthesis, 2009
Copper-catalyzed azide-alkyne 1,3-dipolar cycloadditions (CuAAC) with paramagnetic azide and alkyne building blocks are described. This method provides a route to the synthesis of complex spin-labeled molecules such as amino acids, carbohydrates, drug molecules and biradicals.
Kálmán Hideg, Tamás Kálai, Wayne Hubbell   +2 more
openaire   +1 more source

Kinugasa Reaction under Click Chemistry Conditions

Synlett, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A. Basak, K. Chandra, R. Pal, S. C. Ghosh   +3 more
openaire   +1 more source

Horseradish‐Peroxidase‐Catalyzed Tyrosine Click Reaction

ChemBioChem, 2017
AbstractThe efficiency of protein chemical modification on tyrosine residues with N‐methylluminol derivatives was drastically improved by using horseradish peroxidase (HRP). In the previous method, based on the use of hemin and H2O2, oxidative side reactions such as cysteine oxidation were problematic for functionalization of proteins selectively on ...
Shinichi Sato, Kosuke Nakamura, Hiroyuki Nakamura   +2 more
openaire   +2 more sources

Clusters for alkyne-azide click reactions

Dalton Transactions, 2010
The clusters Ti(6)O(4)(OPr)(8)(OOC(CH(2))(2)C[triple bond]CH)(8) and [Zr(6)O(4)(OH)(4)(OOC(CH(2))(3)C[triple bond]CH)(12)](2) with acetylenic carboxylate ligands were prepared and structurally characterized in solution and in the crystalline state. Model reactions showed that they are suitable candidates for the formation of cluster-based inorganic ...
Philipp, Heinz, Michael, Puchberger, Maria, Bendova, Stefan O, Baumann, Ulrich, Schubert   +4 more
openaire   +2 more sources

Intramolecular Nitrone Interrupted Click Reaction

Organic Letters
We document the intramolecular interception of a Cu-catalyzed azidoalkyne cycloaddition employing a suitably placed nitrone group, providing a simple route to the unprecedented spiro-polyheterocyclic scaffold. The reaction is comprised of a Cu-catalyzed [3 + 2]-cycloaddition of (2-azidoaryl)isatogen with a terminal alkyne and the intramolecular ...
Tejas A. Pothi, Chepuri V. Ramana
openaire   +2 more sources

Radical-mediated click-clip reactions

Science
Click reactions, which are characterized by rapid, high-yielding, and highly selective coupling of two reaction partners, are powerful tools in synthesis but are rarely reversible. Innovative strategies that reverse such couplings in a precise and on-demand manner, enabling a click-clip sequence, would greatly expand the technique’s versatility. Herein,
Jiantao Zhao, Huacheng Yu, Xingchen Jin, Bo Qin, Shan Mei, Jiang-Fei Xu, Xi Zhang   +6 more
openaire   +2 more sources

ChemInform Abstract: Fluorogenic Click Reaction

ChemInform, 2010
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Celine Le Droumaguet, Chao Wang, Qian Wang   +2 more
openaire   +1 more source

Heterovalent Click Reactions on DNA Origami

Bioconjugate Chemistry
Nucleic acid nanoparticles (NANPs) fabricated by using the DNA origami method have broad utility in materials science and bioengineering. Their site-specific, heterovalent functionalization with secondary molecules such as proteins or fluorophores is a unique feature of this technology that drives its utility.
Grant A. Knappe, Jeffrey Gorman, Andrew N. Bigley, Steven P. Harvey, Mark Bathe   +4 more
openaire   +2 more sources

Two-color emissive probes for click reactions

Chem. Commun., 2014
CuAAC is visualized using a BODIPY reaction system by the bathochromic shift of the fluorescence wavelength in ensemble and microscopy experiments. Reaction progress is correlated with chromophore elongation fading out disturbing background fluorescence.
Marcel, Wirtz, Andreas, Grüter, Philipp, Rebmann, Tobias, Dier, Dietrich A, Volmer, Volker, Huch, Gregor, Jung   +6 more
openaire   +2 more sources

Chemoselective Tyrosine Bioconjugation through Sulfate Click Reaction

Chemistry – A European Journal, 2018
AbstractA novel and selective tyrosine functionalization strategy through SuFEx (sulfur fluoride exchange) chemistry is presented. In this approach, free tyrosine (Tyr) reacts selectively with aryl fluorosulfate in the presence of various nucleophilic amino acid residues in bio‐tolerable conditions.
Eun Joung Choi, Dongwook Jung, Jong‐Seo Kim, Yan Lee, B. Moon Kim   +4 more
openaire   +2 more sources