Results 11 to 20 of about 29,874 (272)
How do climbing fibers teach? [PDF]
Frontiers in Neural Circuits, 2012 A commentary on A theory of cerebellar cortex by Marr, D. (1969). J. Physiol. 202, 437–470. A commentary on A theory of cerebellar function by Albus, J. S. (1971). Math. Biosci. 10, 25–61. Four decades ago, Marr and Albus suggested that the climbing fiber (CF) pathway from the inferior olive (IO) to the cerebellum instructs the ...
Thomas Stephen Otis +3 more
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Structural plasticity of climbing fibers and the growth-associated protein GAP-43 [PDF]
Frontiers in Neural Circuits, 2013 Structural plasticity occurs physiologically or after brain damage to adapt or re-establish proper synaptic connections. This capacity depends on several intrinsic and extrinsic determinants that differ between neuron types.
Giorgio eGrasselli, Piergiorgio eStrata
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Cerebellar climbing fibers impact experience-dependent plasticity in the mouse primary somatosensory cortex [PDF]
eLifeIn the cerebellum, climbing fibers (CFs) provide instructive signals for supervised learning at parallel fiber to Purkinje cell synapses. It has not been tested so far whether CF signaling may also influence plasticity in other brain areas. Here, we show
Abby Silbaugh +2 more
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Stimulation within the cuneate nucleus suppresses synaptic activation of climbing fibers [PDF]
Frontiers in Neural Circuits, 2013 Several lines of research have shown that the excitability of the inferior olive is suppressed during different phases of movement. A number of different structures like the cerebral cortex, the red nucleus and the cerebellum have been suggested as ...
Pontus eGeborek +2 more
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Climbing Fibers Control Purkinje Cell Representations of Behavior. [PDF]
J Neurosci, 2017 A crucial issue in understanding cerebellar function is the interaction between simple spike (SS) and complex spike (CS) discharge, the two fundamentally different activity modalities of Purkinje cells. Although several hypotheses have provided insights into the interaction, none fully explains or is completely consistent with the spectrum of ...
Streng ML, Popa LS, Ebner TJ.
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Current concepts of climbing fiber function [PDF]
The Anatomical Record, 1998 This review examines several of the current postulates regarding the function of one of the most intriguing afferent systems in the brain, the climbing fiber system. The fact that these afferents are activated under a variety of conditions has contributed substantially to the diversity of postulates that have been proposed.
J R, Bloedel, V, Bracha
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Droplets climbing a rotating helical fiber [PDF]
The European Physical Journal E, 2015 A liquid droplet is placed on a rotating helical fiber. We find that the droplet may slide down, attach or climb up the fiber. We inspect experimentally the domain of existence of these three behaviors as a function of the geometrical characteristics of the fiber, its angle relatively to the horizontal, the wetting properties of the fluid and the ...
Darbois-Texier, Baptiste +1 more
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Climbing fiber signaling and cerebellar gain control [PDF]
Frontiers in Cellular Neuroscience, 2009 The physiology of climbing fiber signals in cerebellar Purkinje cells has been studied since the early days of electrophysiology. Both the climbing fiber-evoked complex spike and the role of climbing fiber activity in the induction of long-term depression (LTD) at parallel fiber-Purkinje cell synapses have become hallmark features of cerebellar ...
Gen Ohtsuki +4 more
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Climbing fibers predict movement kinematics and performance errors. [PDF]
J Neurophysiol, 2017 Requisite for understanding cerebellar function is a complete characterization of the signals provided by complex spike (CS) discharge of Purkinje cells, the output neurons of the cerebellar cortex. Numerous studies have provided insights into CS function, with the most predominant view being that they are evoked by error events.
Streng ML, Popa LS, Ebner TJ.
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Climbing fibers provide essential instructive signals for associative learning. [PDF]
Nat NeurosciAbstract Supervised learning depends on instructive signals that shape the output of neural circuits to support learned changes in behavior. Climbing fiber (CF) inputs to the cerebellar cortex represent one of the strongest candidates in the vertebrate brain for conveying neural instructive signals.
Silva NT +3 more
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