Results 1 to 10 of about 68,233 (131)

Evidence for Establishing the Clinical Breakpoint of Cefquinome against Haemophilus Parasuis in China [PDF]

Pathogens, 2021
Haemophilus parasuis can cause high morbidity and mortality in swine. Cefquinome possesses excellent antibacterial activity against pathogens causing diseases of the respiratory tract.
Kun Mi, Da Sun, Mei Li, Haihong Hao, Kaixiang Zhou, Zhenli Liu, Zonghui Yuan, Lingli Huang   +7 more
doaj   +2 more sources

Exploration of Clinical Breakpoint of Danofloxacin for Glaesserella parasuis in Plasma and in PELF [PDF]

Antibiotics, 2021
Background: In order to establish the clinical breakpoint (CBP) of danofloxacin against G. parasuis, three cutoff values, including epidemiological cutoff value (ECV), pharmacokinetic-pharmacodynamic (PK-PD) cutoff value (COPD) and clinical cutoff value (
Zihui Xu, Anxiong Huang, Xun Luo, Peng Zhang, Lingli Huang, Xu Wang, Kun Mi, Shiwei Fang, Xiao Huang, Jun Li, Zonghui Yuan, Haihong Hao   +11 more
doaj   +2 more sources

Optimal Regimens and Clinical Breakpoint of Avilamycin Against Clostridium perfringens in Swine Based on PK-PD Study [PDF]

Frontiers in Pharmacology, 2022
Clostridium perfringens causes significant morbidity and mortality in swine worldwide. Avilamycin showed no cross resistance and good activity for treatment of C. perfringens.
Anxiong Huang, Anxiong Huang, Xun Luo, Xun Luo, Zihui Xu, Zihui Xu, Lingli Huang, Lingli Huang, Xu Wang, Xu Wang, Shuyu Xie, Shuyu Xie, Yuanhu Pan, Yuanhu Pan, Shiwei Fang, Shiwei Fang, Zhenli Liu, Zhenli Liu, Zonghui Yuan, Zonghui Yuan, Haihong Hao, Haihong Hao   +21 more
doaj   +2 more sources

Prudent Use of Tylosin for Treatment of Mycoplasma gallisepticum Based on Its Clinical Breakpoint and Lung Microbiota Shift [PDF]

Frontiers in Microbiology, 2021
The aim of this study was to explore the prudent use of tylosin for the treatment of chronic respiratory infectious diseases in chickens caused by Mycoplasma gallisepticum (MG) based on its clinical breakpoint (CBP) and its effect on lung microbiota. The
Anxiong Huang, Anxiong Huang, Shuge Wang, Jinli Guo, Jinli Guo, Yufeng Gu, Yufeng Gu, Jun Li, Lingli Huang, Lingli Huang, Xu Wang, Xu Wang, Yanfei Tao, Yanfei Tao, Zhenli Liu, Zhenli Liu, Zonghui Yuan, Zonghui Yuan, Haihong Hao, Haihong Hao   +19 more
doaj   +2 more sources

Rational Use of Danofloxacin for Treatment of Mycoplasma gallisepticum in Chickens Based on the Clinical Breakpoint and Lung Microbiota Shift [PDF]

Antibiotics, 2022
The study was to explore the rational use of danofloxacin against Mycoplasma gallisepticum (MG) based on its clinical breakpoint (CBP) and the effect on lung microbiota.
Shuge Wang, Anxiong Huang, Yufeng Gu, Jun Li, Lingli Huang, Xu Wang, Yanfei Tao, Zhenli Liu, Congming Wu, Zonghui Yuan, Haihong Hao   +10 more
doaj   +2 more sources

Assessment of long-read strategies for the enrichment of clinically relevant breakpoints in lymphomas: towards a diagnostic implementation [PDF]

Annals of Hematology
Recurrent chromosomal translocations are hallmarks of many hematological malignancies, including lymphomas and leukemias. Accurate breakpoint detection is essential for diagnostics, treatment optimization, and disease monitoring.
Filip Pardy, Kamila Reblova, Hana Svozilova, Boris Tichy, Sarka Pospisilova, Jana Kotaskova, Veronika Navrkalova   +6 more
doaj   +2 more sources

High-Dose Minocycline Improves Outcomes in Acinetobacter baumannii Group Pneumonia: A Propensity-Weighted Cohort Study with MIC-Based Insights for Breakpoint Revision [PDF]

Infectious Diseases and Therapy
Introduction Optimal minocycline dosing for Acinetobacter baumannii group pneumonia remains unclear. We assessed the clinical impact of high-dose (HD) versus standard-dose (SD) minocycline and explored the predictive value of susceptibility breakpoints ...
Yu-Tao Tseng, Yang-Chuan Chen, Yi-Tzu Lee, Po-Hsiang Liao, Dung-Hung Chiang, Po-Liang Chen, Tzu-Wen Huang, Yung-Chih Wang   +7 more
doaj   +2 more sources

Microbiological, Clinical, and Pharmacokinetic/Pharmacodynamic Data to Support EUCAST Aztreonam–Avibactam Minimum Inhibitory Concentration Susceptibility Breakpoints Against Enterobacterales [PDF]

Infectious Diseases and Therapy
Introduction Aztreonam–avibactam was approved for adults with limited treatment options for multiple infections due to aerobic Gram-negative organisms in the European Union and for complicated intra-abdominal infection in the US, following the phase 3 ...
Susan R. Raber, Rujia Xie, Halley Rogers, Elena Soto, Francis F. Arhin, Gregory G. Stone, Heidi Leister-Tebbe, Joseph W. Chow   +7 more
doaj   +2 more sources

Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs [PDF]

, 2018
Four full-sibling intact male Miniature Poodles were evaluated at 4–19 months of age. One was clinically normal and three were affected. All affected dogs were reluctant to exercise and had generalised muscle atrophy, a stiff gait and a markedly elevated
A Aartsma-Rus, A McKenna, Alberta de Stefani, Anita Shea, AP Monaco, AV Winnard, BA Valentine, BF Smith, BJ Cooper, C Le Guiner, C Pichavant, CA Collins, CA Jenkins, CA Wetterman, Carlos E. Ambrósio, CT Caskey, DE Cole, DJ VanBelzen, Elsa Beltrán, EM Hoogerwaard, EM Hoogerwaard, EP Hoffman, F Daoud, G Anil, G Bulfield, G. Diane Shelton, GD Shelton, GD Shelton, GD Shelton, GD Shelton, GL Walmsley, H Li, JA Goldstein, JL Carpenter, JN Kornegay, JN Kornegay, JR Mendell, JW McGreevy, K Bushby, K Nakamura, KJ Livak, KJ Nowak, Ling T. Guo, Lluís Sánchez, Louise M. Burmeister, LT Guo, Luisa De Risio, M Koenig, N Klymiuk, N Winand, NJ Olby, NJ Sharp, PP Nghiem, S Atencia-Fernandez, S Pouwels, S Rozen, SJ Schatzberg, SJ Schatzberg, T Larcher, U Francke, V Dubowitz, V Ricotti, W El Nemer, WI Baltzer   +63 more
core   +14 more sources

Diagnostic utility of GenoType MTBDRsl assay for the detection of moxifloxacin-resistant mycobacterium tuberculosis, as compared to phenotypic method and whole-genome sequencing

International Journal of Mycobacteriology, 2022
Background: Recently, moxifloxacin (MFX)-resistant results of Mycobacterium tuberculosis (Mtb) obtained by GenoType MTBDRsl (second-line line probe assay [SL-LPA]) have been stratified to determine their resistance level; however, its accuracy has not ...
Raj Narayan Yadav, Manpreet Bhalla, Gavish Kumar, Grish C Sah, Ravindra Kumar Dewan, Ritu Singhal   +5 more
doaj   +1 more source