Results 181 to 190 of about 579,638 (359)

Bacterial Minicell‐Based Biohybrid Sub‐micron Swimmers for Targeted Cargo Delivery

open access: yesAdvanced Science, EarlyView.
Bacterial minicells, vesicles derived from engineered E. coli, offer promising sub‐micron scale biohybrid swimmers for targeted cargo delivery. Purified with over 99% efficiency while retaining motility, they are functionalized with MNPs for controlled movement.
Saadet Fatma Baltaci   +4 more
wiley   +1 more source

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan   +10 more
wiley   +1 more source

Appraisal of Clinical Competence during Clerkships

open access: bronze, 2001
Mathieu Nendaz   +5 more
openalex   +1 more source

Senescence‐Inducing Therapy Sequential NIR‐II Mild Photothermal/Senolytic Therapy of Triple Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Targeting triple‐negative breast cancer remains challenging due to limited therapies and drug resistance. A sequential theranostic strategy combining palbociclib‐induced senescence (enhancing heat sensitivity via HSP70 downregulation) with an NIR‐II nanoplatform (IQ NPs) for mild photothermal therapy (PTT) and quercetin‐mediated senolysis is developed.
Liya Yu   +8 more
wiley   +1 more source

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