Results 231 to 240 of about 599,878 (339)

Log of Clinical Competence [PDF]

core  

An Engineered Probiotic Consortium Based on Quorum‐Sensing for Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This work develops an engineered probiotic consortium sensing pH, hypoxia, and lactate in the tumor microenvironment. It releases a lactate‐depleting enzyme (LdhA) and a PD‐L1 nanobody. In humanized mouse models (MC38 and HT‐29 tumors), it achieves durable oscillations, suppresses tumors, activates CD8+, CD4+, IFN‐γ+ T cells, and reduces Foxp3 ...
Yufei Guo, Mengxue Gao, Lina Wang, Haibin Yuan, Jianan Yin, Jiahao Wu, Xinran Gao, Zhixin Zhu, Yan Zhang, Zichen Wang, He Huang, Guangbo Kang   +11 more
wiley   +1 more source

Impact of Simulation-Based Medical Education on Pre-clerkship Medical Students' Confidence in Key Areas of Clinical Competence: An Exploratory Pre- and Post-survey Study. [PDF]

Cureus
Friesen DK, Rebello L, Reel R, Espinosa V, Lelj Garolla Di Bard B.   +4 more
europepmc   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Advancing the assessment of clinical competence in Latin America: a scoping review of OSCE implementation and challenges in resource-limited settings. [PDF]

BMC Med Educ
Armijo-Rivera S, Fuenzalida-Muñoz B, Vicencio-Clarke S, Elbers-Arce A, Bozzo-Navarrete S, Kunakov N, Miranda-Hurtado C, Shibao-Miyasato H, Sanhueza J, Cornejo C, Soublette A, Sandoval AM, Casas-Bueno FC, Delgado X.   +13 more
europepmc   +1 more source

ACCF/AHA/SCAI 2013 Update of the Clinical Competence Statement on Coronary Artery Interventional Procedures [PDF]

, 2013
John Harold, Theodore A. Bass, Thomas M. Bashore, Ralph G. Brindis, John E. Brush, James A. Burke, Gregory Dehmer, Yuri A. Deychak, Hani Jneid, James G. Jollis, Joel S. Landzberg, Glenn N. Levine, James B. McClurken, John C. Messenger, Issam Moussa, J. Brent Muhlestein, Richard M. Pomerantz, Timothy A. Sanborn, Chittur A. Sivaram, Christopher J. White, Eric S. Williams, John Harold, Shalom Jacobovitz, William J. Oetgen, Charlene May, Dawn R. Phoubandith, Grace D. Ronan, Erin A. Barrett, Donna K. Arnett, Nancy Brown, Rose Marie Robertson, Gayle R. Whitman, Judy L. Bezanson, Theodore A. Bass, Norm Linsky, Joel Harder   +35 more
openalex   +1 more source

Dual‐Pedicle Tissue‐Engineered Trachea Promotes Biomimetic Cartilaginous Framework, Vascularization, and Epithelial Lining for Long‐Segment Tracheal Reconstruction

Advanced Science, EarlyView.
Overcoming the limitations of conventional grafts, a biomimetic trachea with two independent vascular pedicles enables rapid integration and sustained patency. This approach markedly improves survival rates, restores the epithelial barrier, and promotes regenerative pathways, presenting a transformative paradigm for clinical application.
Ziming Wang, Yuming Wang, Zihao Chen, Erji Gao, Liang Guo, Juanjuan Li, Siqiang Zheng, Jiaoyu Yi, Zhe‐Sheng Chen, Bo Tao   +9 more
wiley   +1 more source

A Dynamic Interaction: Supervisors' Reasoning About Nursing Students' Conditions for Learning and Development of Clinical Competence. A Focus Group Study. [PDF]

Nurs Open
Löfgren U, Lindberg B, Strömbäck U, Wälivaara BM.   +3 more
europepmc   +1 more source

Development of a Computerized Model of Performance-Based Measurement to Facilitate and Evaluate New Graduate Nurses' Clinical Competence [PDF]

, 2013
Shwu‐Ru Liou, Ching‐Yu Cheng, Hsiu‐Chen Liu, Shu‐Ling Tsai   +3 more
openalex   +1 more source

Contemplating Competence: Three Mediations [PDF]

, 2016
Wegner, Judith Welch
core   +1 more source