Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou +10 more
wiley +1 more source
The effect of combined training program on clinical competence and professional commitment of perioperative nursing students in laparoscopic surgery: a quasi-experimental study. [PDF]
Bagheri M +5 more
europepmc +1 more source
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv +11 more
wiley +1 more source
Enhancing Teamwork and Clinical Competence in Radiotherapy Education: Integrating TeamSTEPPS with PEARLS Structured Debriefing in Scenario-Based Simulations. [PDF]
Liu G, Lan T, E M, He Y, Hu H.
europepmc +1 more source
Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini +8 more
wiley +1 more source
Comparison of A Mini-Clinical evaluation exercise with the routine logbook in assessing clinical competence of operating room trainees: A parallel randomized controlled trial. [PDF]
Bagheri S +4 more
europepmc +1 more source
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua +6 more
wiley +1 more source
Artificial intelligence in psychiatric education: Enhancing clinical competence through simulation.
Ajluni V.
europepmc +1 more source
Impact of Simulation-Based Medical Education on Pre-clerkship Medical Students' Confidence in Key Areas of Clinical Competence: An Exploratory Pre- and Post-survey Study. [PDF]
Friesen DK +4 more
europepmc +1 more source

