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Definition of clinical immunology around the globe [PDF]

Frontiers in Immunology
Immunology has gradually become a core part of many medical specialties. Immune cells and immune mediators are now known to participate in the pathogenesis of a wide variety of diseases and therapies based on the modulation of immune function are ...
José C. Crispín, José C. Crispín, José C. Crispín, Tineke Cantaert, Tineke Cantaert, Alberto Pinzon-Charry, Alberto Pinzon-Charry, Alberto Pinzon-Charry, Domenico Mavilio, Domenico Mavilio, Domenico Mavilio, Ahmed Seri, Ahmed Seri, Pierre Miossec, Pierre Miossec   +14 more
doaj   +2 more sources

Clinical immunology in chromatinopathies: a scoping review [PDF]

Frontiers in Immunology
BackgroundChromatinopathies (CP) are a subclass of monogenic neurodevelopmental disorders caused by germline mutations in genes involved in epigenetic regulation.
Dieke Jans, Burcu Al, Arianne Bouman, Arianne Bouman, Joyce M. Geelen, Tjitske Kleefstra, Tjitske Kleefstra, Tjitske Kleefstra, Katarzyna Placek   +8 more
doaj   +2 more sources

Clinical immunology [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2005
doaj   +4 more sources

Clinical immunology [PDF]

Postgraduate Medical Journal, 1991
Clinical immunology is a medical specialty with a pathogenetic rather than organ-based focus. The main clinical areas covered are allergic disease, autoimmune disease, lymphoproliferative disease, transplantation and immunodeficiency. The role and training of the physician immunologist and the organ-based specialist with an interest are outlined.
J. Brostoff, G.K. Scadding, D. Male, I.M. Roitt   +3 more
  +7 more sources

Association Between Baseline Therapy and Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome

Frontiers in Immunology, 2022
BackgroundCurrent standard-of-care treatments for hypereosinophilic syndrome (HES) include oral corticosteroids (OCS) and immunosuppressive/cytotoxic (IS/CT) therapies.
Andreas Reiter, Guillaume Lefevre, Maria C. Cid, Namhee Kwon, Eleni Mavropolou, Steven W. Yancey, Jonathan Steinfeld   +6 more
doaj   +1 more source

Evaluation of Subjects Experiencing Allergic Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Characteristics and Drugs Involved

Frontiers in Pharmacology, 2020
Non-steroidal anti-inflammatory drugs (NSAIDs), the most commonly prescribed and consumed medicines worldwide, are the main triggers of drug hypersensitivity reactions (DHRs).
Natalia Pérez-Sánchez, Natalia Pérez-Sánchez, Inmaculada Doña, Gador Bogas, María Salas, Almudena Testera, José A. Cornejo-García, María J. Torres, María J. Torres, María J. Torres, María J. Torres   +10 more
doaj   +1 more source

Prevalence of anaphylaxis and prescription rates of epinephrine auto-injectors in urban and rural areas of Korea [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Despite the clinical importance anaphylaxis and the recent increase in its occurrence, studies regarding the epidemiology of anaphylaxis, risk factors for anaphylaxis, and epinephrine auto-injector (EAI) prescription status for patients ...
Hyunseok Cho, Jae-Woo Kwon
doaj   +1 more source

What makes TMB an ambivalent biomarker for immunotherapy? A subtle mismatch between the sample-based design of variant callers and real clinical cohort

Frontiers in Immunology, 2023
Tumor mutation burden (TMB) is a widely recognized biomarker for predicting the efficacy of immunotherapy. However, its use still remains highly controversial.
Yuqian Liu, Yuqian Liu, Shenjie Wang, Shenjie Wang, Yixuan Wang, Yifei Li, Xiaoyan Zhu, Xiaoyan Zhu, Xin Lai, Xin Lai, Xuanping Zhang, Xuanping Zhang, Xuqi Li, Xiao Xiao, Xiao Xiao, Jiayin Wang, Jiayin Wang   +16 more
doaj   +1 more source

A Joint Model Considering Measurement Errors for Optimally Identifying Tumor Mutation Burden Threshold

Frontiers in Genetics, 2022
Tumor mutation burden (TMB) is a recognized stratification biomarker for immunotherapy. Nevertheless, the general TMB-high threshold is unstandardized due to severe clinical controversies, with the underlying cause being inconsistency between multiple ...
Yixuan Wang, Xin Lai, Jiayin Wang, Jiayin Wang, Jiayin Wang, Ying Xu, Xuanping Zhang, Xiaoyan Zhu, Yuqian Liu, Yang Shao, Yang Shao, Li Zhang, Wenfeng Fang   +12 more
doaj   +1 more source

Integrated machine learning approaches for flow cytometric quantification of myeloid-derived suppressor cells in acute sepsis

Frontiers in Immunology, 2022
Highly heterogeneous cell populations require multiple flow cytometric markers for appropriate phenotypic characterization. This exponentially increases the complexity of 2D scatter plot analyses and exacerbates human errors due to variations in manual ...
Anthony S. Bonavia, Anthony S. Bonavia, Abigail Samuelsen, Joshua Luthy, E. Scott Halstead   +4 more
doaj   +1 more source