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Clinical immunology [PDF]

open access: goldRevista do Instituto de Medicina Tropical de São Paulo, 2005
Zoilo Pires dè Camargo
doaj   +4 more sources

Definition of clinical immunology around the globe [PDF]

open access: yesFrontiers in Immunology
Immunology has gradually become a core part of many medical specialties. Immune cells and immune mediators are now known to participate in the pathogenesis of a wide variety of diseases and therapies based on the modulation of immune function are ...
José C. Crispín   +14 more
doaj   +2 more sources

Basic and clinical immunology [PDF]

open access: bronzeJournal of Allergy and Clinical Immunology, 2003
Progress in immunology continues to grow exponentially every year. New applications of this knowledge are being developed for a broad range of clinical conditions. Conversely, the study of primary and secondary immunodeficiencies is helping to elucidate the intricate mechanisms of the immune system.
Javier Chinen, William T. Shearer
openalex   +5 more sources

Modeling-Enabled Systems Nutritional Immunology

open access: yesFrontiers in Nutrition, 2016
This review highlights the fundamental role of nutrition in the maintenance of health, the immune response and disease prevention. Emerging global mechanistic insights in the field of nutritional immunology cannot be gained through reductionist methods ...
Meghna Verma   +2 more
exaly   +3 more sources

Association Between Baseline Therapy and Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome

open access: yesFrontiers in Immunology, 2022
BackgroundCurrent standard-of-care treatments for hypereosinophilic syndrome (HES) include oral corticosteroids (OCS) and immunosuppressive/cytotoxic (IS/CT) therapies.
Andreas Reiter   +6 more
doaj   +1 more source

Prevalence of anaphylaxis and prescription rates of epinephrine auto-injectors in urban and rural areas of Korea [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims Despite the clinical importance anaphylaxis and the recent increase in its occurrence, studies regarding the epidemiology of anaphylaxis, risk factors for anaphylaxis, and epinephrine auto-injector (EAI) prescription status for patients ...
Hyunseok Cho, Jae-Woo Kwon
doaj   +1 more source

A Joint Model Considering Measurement Errors for Optimally Identifying Tumor Mutation Burden Threshold

open access: yesFrontiers in Genetics, 2022
Tumor mutation burden (TMB) is a recognized stratification biomarker for immunotherapy. Nevertheless, the general TMB-high threshold is unstandardized due to severe clinical controversies, with the underlying cause being inconsistency between multiple ...
Yixuan Wang   +12 more
doaj   +1 more source

Integrated machine learning approaches for flow cytometric quantification of myeloid-derived suppressor cells in acute sepsis

open access: yesFrontiers in Immunology, 2022
Highly heterogeneous cell populations require multiple flow cytometric markers for appropriate phenotypic characterization. This exponentially increases the complexity of 2D scatter plot analyses and exacerbates human errors due to variations in manual ...
Anthony S. Bonavia   +4 more
doaj   +1 more source

What makes TMB an ambivalent biomarker for immunotherapy? A subtle mismatch between the sample-based design of variant callers and real clinical cohort

open access: yesFrontiers in Immunology, 2023
Tumor mutation burden (TMB) is a widely recognized biomarker for predicting the efficacy of immunotherapy. However, its use still remains highly controversial.
Yuqian Liu   +16 more
doaj   +1 more source

The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection

open access: yesFrontiers in Immunology, 2020
The RTS,S/AS01 vaccine provides partial protection against Plasmodium falciparum infection but determinants of protection and/or disease are unclear. Previously, anti-circumsporozoite protein (CSP) antibody titers and blood RNA signatures were associated
Ying Du   +19 more
doaj   +1 more source

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