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Clinical immunology [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2005
Zoilo Pires dè Camargo
doaj   +4 more sources

Definition of clinical immunology around the globe [PDF]

Frontiers in Immunology
Immunology has gradually become a core part of many medical specialties. Immune cells and immune mediators are now known to participate in the pathogenesis of a wide variety of diseases and therapies based on the modulation of immune function are ...
José C. Crispín, José C. Crispín, José C. Crispín, Tineke Cantaert, Tineke Cantaert, Alberto Pinzon-Charry, Alberto Pinzon-Charry, Alberto Pinzon-Charry, Domenico Mavilio, Domenico Mavilio, Domenico Mavilio, Ahmed Seri, Ahmed Seri, Pierre Miossec, Pierre Miossec   +14 more
doaj   +2 more sources

Basic and clinical immunology [PDF]

Journal of Allergy and Clinical Immunology, 2003
Progress in immunology continues to grow exponentially every year. New applications of this knowledge are being developed for a broad range of clinical conditions. Conversely, the study of primary and secondary immunodeficiencies is helping to elucidate the intricate mechanisms of the immune system.
Javier Chinen, William T. Shearer
openaire   +5 more sources

Modeling-Enabled Systems Nutritional Immunology

Frontiers in Nutrition, 2016
This review highlights the fundamental role of nutrition in the maintenance of health, the immune response and disease prevention. Emerging global mechanistic insights in the field of nutritional immunology cannot be gained through reductionist methods ...
Meghna Verma, Raquel Hontecillas, Vida Abedi   +2 more
exaly   +3 more sources

Association Between Baseline Therapy and Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome

Frontiers in Immunology, 2022
BackgroundCurrent standard-of-care treatments for hypereosinophilic syndrome (HES) include oral corticosteroids (OCS) and immunosuppressive/cytotoxic (IS/CT) therapies.
Andreas Reiter, Guillaume Lefevre, Maria C. Cid, Namhee Kwon, Eleni Mavropolou, Steven W. Yancey, Jonathan Steinfeld   +6 more
doaj   +1 more source

Ocular Motor Abnormalities in Anti-IgLON5 Disease

Frontiers in Immunology, 2021
ObjectiveAnti-IgLON5 disease forms an interface between neuroinflammation and neurodegeneration and includes clinical phenotypes that are often similar to those of neurodegenerative diseases.
Stefan Macher, Ivan Milenkovic, Tobias Zrzavy, Romana Höftberger, Stefan Seidel, Evelyn Berger-Sieczkowski, Thomas Berger, Paulus S. Rommer, Gerald Wiest   +8 more
doaj   +1 more source

Prevalence of anaphylaxis and prescription rates of epinephrine auto-injectors in urban and rural areas of Korea [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Despite the clinical importance anaphylaxis and the recent increase in its occurrence, studies regarding the epidemiology of anaphylaxis, risk factors for anaphylaxis, and epinephrine auto-injector (EAI) prescription status for patients ...
Hyunseok Cho, Jae-Woo Kwon
doaj   +1 more source

TMBserval: a statistical explainable learning model reveals weighted tumor mutation burden better categorizing therapeutic benefits

Frontiers in Immunology, 2023
A high tumor mutation burden (TMB) is known to drive the response to immune checkpoint inhibitors (ICI) and is associated with favorable prognoses. However, because it is a one-dimensional numerical representation of non-synonymous genetic alterations ...
Yixuan Wang, Jiayin Wang, Wenfeng Fang, Xiao Xiao, Quan Wang, Jian Zhao, Jingjing Liu, Shuanying Yang, Yuqian Liu, Xin Lai, Xiaofeng Song   +10 more
doaj   +1 more source

A Joint Model Considering Measurement Errors for Optimally Identifying Tumor Mutation Burden Threshold

Frontiers in Genetics, 2022
Tumor mutation burden (TMB) is a recognized stratification biomarker for immunotherapy. Nevertheless, the general TMB-high threshold is unstandardized due to severe clinical controversies, with the underlying cause being inconsistency between multiple ...
Yixuan Wang, Xin Lai, Jiayin Wang, Jiayin Wang, Jiayin Wang, Ying Xu, Xuanping Zhang, Xiaoyan Zhu, Yuqian Liu, Yang Shao, Yang Shao, Li Zhang, Wenfeng Fang   +12 more
doaj   +1 more source

The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection

Frontiers in Immunology, 2020
The RTS,S/AS01 vaccine provides partial protection against Plasmodium falciparum infection but determinants of protection and/or disease are unclear. Previously, anti-circumsporozoite protein (CSP) antibody titers and blood RNA signatures were associated
Ying Du, Ethan G. Thompson, Julius Muller, Joseph Valvo, Jackie Braun, Smitha Shankar, Robert A. van den Berg, Erik Jongert, Drew Dover, Jerald Sadoff, Jenny Hendriks, Malcolm J. Gardner, W. Ripley Ballou, Jason A. Regules, Robbert van der Most, Alan Aderem, Christian F. Ockenhouse, Adrian V. Hill, Ulrike Wille-Reece, Daniel E. Zak   +19 more
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