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Definition of clinical immunology around the globe [PDF]

open access: yesFrontiers in Immunology
Immunology has gradually become a core part of many medical specialties. Immune cells and immune mediators are now known to participate in the pathogenesis of a wide variety of diseases and therapies based on the modulation of immune function are ...
José C. Crispín   +14 more
doaj   +2 more sources

Clinical immunology in chromatinopathies: a scoping review [PDF]

open access: yesFrontiers in Immunology
BackgroundChromatinopathies (CP) are a subclass of monogenic neurodevelopmental disorders caused by germline mutations in genes involved in epigenetic regulation.
Dieke Jans   +8 more
doaj   +2 more sources

Clinical immunology [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2005
doaj   +4 more sources

Clinical immunology [PDF]

open access: yesPostgraduate Medical Journal, 1991
Clinical immunology is a medical specialty with a pathogenetic rather than organ-based focus. The main clinical areas covered are allergic disease, autoimmune disease, lymphoproliferative disease, transplantation and immunodeficiency. The role and training of the physician immunologist and the organ-based specialist with an interest are outlined.
J. Brostoff   +3 more
  +7 more sources

Association Between Baseline Therapy and Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome

open access: yesFrontiers in Immunology, 2022
BackgroundCurrent standard-of-care treatments for hypereosinophilic syndrome (HES) include oral corticosteroids (OCS) and immunosuppressive/cytotoxic (IS/CT) therapies.
Andreas Reiter   +6 more
doaj   +1 more source

Prevalence of anaphylaxis and prescription rates of epinephrine auto-injectors in urban and rural areas of Korea [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims Despite the clinical importance anaphylaxis and the recent increase in its occurrence, studies regarding the epidemiology of anaphylaxis, risk factors for anaphylaxis, and epinephrine auto-injector (EAI) prescription status for patients ...
Hyunseok Cho, Jae-Woo Kwon
doaj   +1 more source

What makes TMB an ambivalent biomarker for immunotherapy? A subtle mismatch between the sample-based design of variant callers and real clinical cohort

open access: yesFrontiers in Immunology, 2023
Tumor mutation burden (TMB) is a widely recognized biomarker for predicting the efficacy of immunotherapy. However, its use still remains highly controversial.
Yuqian Liu   +16 more
doaj   +1 more source

A Joint Model Considering Measurement Errors for Optimally Identifying Tumor Mutation Burden Threshold

open access: yesFrontiers in Genetics, 2022
Tumor mutation burden (TMB) is a recognized stratification biomarker for immunotherapy. Nevertheless, the general TMB-high threshold is unstandardized due to severe clinical controversies, with the underlying cause being inconsistency between multiple ...
Yixuan Wang   +12 more
doaj   +1 more source

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