Results 31 to 40 of about 486,600 (333)

What is clinical immunology? [PDF]

Journal of Clinical Pathology, 1981
The clinical and laboratory details of 10 patients with predominantly immunological problems were circulated to selected physicians in different forms of hospital practice. In general, these physicians would prefer to select their own immunological tasks and could get these performed in their clinical pathology laboratories or regional immunology ...
openaire   +3 more sources

A case report of simultaneous PML-IRIS during corticosteroids tapering in a patient with an anti-synthetase syndrome [v1; ref status: indexed, http://f1000r.es/2l6]

F1000Research, 2013
We report a case of simultaneous progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome (PML-IRIS) during corticosteroid tapering in a patient with an anti-synthetase syndrome.
Guillaume Martin-Blondel, David Brassat, Hervé Dumas, Emmanuelle Uro-Coste, Daniel Adoue, Hans Lassmann, Michel Clanet   +6 more
doaj   +1 more source

Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-β blockade in HPV-unrelated head and neck cancer

The Journal of Clinical Investigation, 2023
BACKGROUND Head and neck squamous cell carcinoma not associated with HPV (HPV-unrelated HNSCC) is associated with a high rate of recurrence and poor survival.METHODS We conducted a clinical trial in 14 patients with newly diagnosed HPV-unrelated HNSCC to
Jason M. Redman, Jay Friedman, Yvette Robbins, Cem Sievers, Xinping Yang, Wiem Lassoued, Andrew Sinkoe, Antonios Papanicolau-Sengos, Chyi-Chia Lee, Jennifer L. Marte, Evrim Turkbey, Wojtek Mydlarz, Arjun Joshi, Nyall R. London Jr., Matthew Pierce, Rodney Taylor, Steven Hong, Andy Nguyen, Patrick Soon-Shiong, Jeffrey Schlom, James L. Gulley, Clint T. Allen   +21 more
doaj   +1 more source

Bayesian Models and Decision Algorithms for Complex Early Phase Clinical Trials [PDF]

Statistical Science 2010, Vol. 25, No. 2, 227-244, 2010
An early phase clinical trial is the first step in evaluating the effects in humans of a potential new anti-disease agent or combination of agents. Usually called "phase I" or "phase I/II" trials, these experiments typically have the nominal scientific goal of determining an acceptable dose, most often based on adverse event probabilities.
arxiv   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The role of out-of-class work of doctor-interns in improving qualitive academic progress on clinical immunology and allergology under the primary specialization “Internal diseases”.

Medičnì Perspektivi, 2018
The use of independent out-of-class work of interns on the specialty "Internal diseases" in the section of clinical immunology and allergology promoted the improvement of the qualitative success of interns.
G. P. Kuz'mina, V. A. Potabashniy, V. I. Fesenko, O. V. Knjazjeva, V. Je. Azarenko, A. M. Vasylenko, V. E. Khatsko   +6 more
doaj   +1 more source

International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem

World Allergy Organization Journal, 2017
Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the ...
Mario Sánchez-Borges, Enrique Fernandez-Caldas, Wayne R. Thomas, Martin D. Chapman, Bee Wah Lee, Luis Caraballo, Nathalie Acevedo, Fook Tim Chew, Ignacio J. Ansotegui, Leili Behrooz, Wanda Phipatanakul, Roy Gerth van Wijk, Demoly Pascal, Nelson Rosario, Motohiro Ebisawa, Mario Geller, Santiago Quirce, Susanne Vrtala, Rudolf Valenta, Markus Ollert, Giorgio Walter Canonica, Moises A. Calderón, Charles S. Barnes, Adnan Custovic, Suwat Benjaponpitak, Arnaldo Capriles-Hulett   +25 more
doaj   +3 more sources

Using Clinical Cases to Restore Basic Science Immunology Knowledge in Physicians and Senior Medical Students

Frontiers in Immunology, 2020
The majority of medical students and many physicians find basic science immunology confusing and the teaching of immunology to be uninteresting. Physicians undergoing training in a range of disciplines treat patients with immunological disease, including
Mohammed Yousuf Karim, Mohammed Yousuf Karim   +1 more
doaj   +1 more source

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue [PDF]

Science Translational Medicine, American Association for the Advancement of Science, 2017, 9 (405), pp.eaal5088, 2017
Dengue is the most prevalent arthropod-borne viral disease. Clinical symptoms of dengue virus (DENV) infection range from classical mild dengue fever to severe, life-threatening dengue shock syndrome. However, most DENV infections cause few or no symptoms.
arxiv   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source