Results 21 to 30 of about 2,097,223 (266)

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Management and monitoring strategies for severe cerebral malaria: a guide for the intensivist

Annals of Intensive Care
Severe malaria, caused by Plasmodium falciparum, poses a critical public health challenge, with cerebral malaria (CM) representing its most severe and life-threatening neurological manifestation. Defined by impaired consciousness (Glasgow Coma Score 
Sonila Vathi, Alberto Corriero, Edith Elianna Rodríguez, Anthony Moreau, Elisa Gouvea Bogossian, Marta Baggiani, Maya Hites, Romain Sonneville, Fabio Silvio Taccone, Michele Salvagno   +9 more
doaj   +1 more source

Exploration of the immunogenetic landscape of hyperprogressive disease after combined immunotherapy in cancer patients

iScience, 2023
Summary: The immune-genetic changes that occur in cancer patients experiencing hyperprogressive disease (HPD) during combined immunotherapy are unclear.
Caifeng Gong, Wen Zhang, Yongkun Sun, Jianzhong Shou, Zhichao Jiang, Tianyi Liu, Shengzhou Wang, Jun Liu, Ying Sun, Aiping Zhou   +9 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Hemostatic abnormalities after trauma resuscitation: challenges and strategies in caring for the critically injured patient

Annals of Intensive Care
Severe polytrauma and hemorrhage is a common and life-threatening condition often leading to intensive care unit admission for those who survive their initial injury.
Christopher R. Reed, Nicola Curry, Nicole P. Juffermans, Matthew D. Neal   +3 more
doaj   +1 more source

Investigating the barriers to clinical education among medical students in Iran: A narrative review study

Journal of Family Medicine and Primary Care, 2022
Various factors can affect the clinical education of medical students. The main purpose of this study was to investigate the barriers to clinical educational related to medical students in Iranian universities of medical sciences.
Sahar Vahdat, Nazanin Tanhaei, Somayeh Najafi, Mohammad Hossein Salemi, Fereshteh Karbasian   +4 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

The metabolic response to stress in critical illness: updated review on the pathophysiological mechanisms, consequences, and therapeutic implications

Annals of Intensive Care
The understanding of the response to stress in critical illness has significantly improved in recent years. These adaptations unfold across acute, subacute, and chronic phases, with an early adaptive catabolic state, marked anabolic resistance, and a ...
Raphael Mottale, Claire Dupuis, Sylwia Szklarzewska, Jean-Charles Preiser   +3 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Neuromuscular blockade and their monitoring in the intensive care unit: a multicenter observational prospective study

Annals of Intensive Care
Background: Neuromuscular blocking agents may improve outcomes in specific conditions, including the early phase of acute respiratory distress syndrome.
Bertrand Hermann, Guillaume Decormeille, Tiphanie Gobé, Nathanaël Mangeard, Adel Maamar, Saria Sayadi, Bénédicte Pernod, Nadine Robquin, Jean-Pierre Ponthus, Sophie Le Potier, Pierre Bouju, Angélique Balabanian, Antoine Frouin, Sébastien Moschietto, Gwenaelle Jacq, Emeline Villemont, Clémence Houbé, Anaïs Queyreau, Célina Morand, Florence Boissier, Jean-Baptiste Lascarrou, Sabine Valera, Sami Hraiech, Laure Clouet, Gaël Piton, Cindérella Noël, Anne Joosten, Cécilia Tabra Osorio, Adrien Constan, Jérôme Cecchini, Gwennaelle Mercier, Arnaud Bruyneel, Chloé Villamaux, François Pousset, Nicholas Heming, Laurent Poiroux, Jean-François Llitjos, Saber Davide Barbar   +37 more
doaj   +1 more source