Results 21 to 30 of about 2,224,952 (265)

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Management and monitoring strategies for severe cerebral malaria: a guide for the intensivist

Annals of Intensive Care
Severe malaria, caused by Plasmodium falciparum, poses a critical public health challenge, with cerebral malaria (CM) representing its most severe and life-threatening neurological manifestation. Defined by impaired consciousness (Glasgow Coma Score 
Sonila Vathi, Alberto Corriero, Edith Elianna Rodríguez, Anthony Moreau, Elisa Gouvea Bogossian, Marta Baggiani, Maya Hites, Romain Sonneville, Fabio Silvio Taccone, Michele Salvagno   +9 more
doaj   +1 more source

Exploration of the immunogenetic landscape of hyperprogressive disease after combined immunotherapy in cancer patients

iScience, 2023
Summary: The immune-genetic changes that occur in cancer patients experiencing hyperprogressive disease (HPD) during combined immunotherapy are unclear.
Caifeng Gong, Wen Zhang, Yongkun Sun, Jianzhong Shou, Zhichao Jiang, Tianyi Liu, Shengzhou Wang, Jun Liu, Ying Sun, Aiping Zhou   +9 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Hemostatic abnormalities after trauma resuscitation: challenges and strategies in caring for the critically injured patient

Annals of Intensive Care
Severe polytrauma and hemorrhage is a common and life-threatening condition often leading to intensive care unit admission for those who survive their initial injury.
Christopher R. Reed, Nicola Curry, Nicole P. Juffermans, Matthew D. Neal   +3 more
doaj   +1 more source

Investigating the barriers to clinical education among medical students in Iran: A narrative review study

Journal of Family Medicine and Primary Care, 2022
Various factors can affect the clinical education of medical students. The main purpose of this study was to investigate the barriers to clinical educational related to medical students in Iranian universities of medical sciences.
Sahar Vahdat, Nazanin Tanhaei, Somayeh Najafi, Mohammad Hossein Salemi, Fereshteh Karbasian   +4 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

The metabolic response to stress in critical illness: updated review on the pathophysiological mechanisms, consequences, and therapeutic implications

Annals of Intensive Care
The understanding of the response to stress in critical illness has significantly improved in recent years. These adaptations unfold across acute, subacute, and chronic phases, with an early adaptive catabolic state, marked anabolic resistance, and a ...
Raphael Mottale, Claire Dupuis, Sylwia Szklarzewska, Jean-Charles Preiser   +3 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Neuromuscular blockade and their monitoring in the intensive care unit: a multicenter observational prospective study

Annals of Intensive Care
Background: Neuromuscular blocking agents may improve outcomes in specific conditions, including the early phase of acute respiratory distress syndrome.
Bertrand Hermann, Guillaume Decormeille, Tiphanie Gobé, Nathanaël Mangeard, Adel Maamar, Saria Sayadi, Bénédicte Pernod, Nadine Robquin, Jean-Pierre Ponthus, Sophie Le Potier, Pierre Bouju, Angélique Balabanian, Antoine Frouin, Sébastien Moschietto, Gwenaelle Jacq, Emeline Villemont, Clémence Houbé, Anaïs Queyreau, Célina Morand, Florence Boissier, Jean-Baptiste Lascarrou, Sabine Valera, Sami Hraiech, Laure Clouet, Gaël Piton, Cindérella Noël, Anne Joosten, Cécilia Tabra Osorio, Adrien Constan, Jérôme Cecchini, Gwennaelle Mercier, Arnaud Bruyneel, Chloé Villamaux, François Pousset, Nicholas Heming, Laurent Poiroux, Jean-François Llitjos, Saber Davide Barbar   +37 more
doaj   +1 more source