Results 71 to 80 of about 2,930,507 (308)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Innovating Residency Orientation Training. A Multi-Modal, Gamified Approach to Clinical Onboarding at Fondazione Policlinico Universitario Campus Bio-Medico

Excellence and Innovation in Learning and Teaching
This study assesses the effectiveness of “Resident Day,” a multi-modal orientation program at Fondazione Policlinico Universitario Campus Bio-Medico for newly enrolled medical residents. The program combines traditional lectures, experiential simulations,
Claudio Pensieri, Sabrina Saccoccia, Rosanna Alloni   +2 more
doaj   +1 more source

The impact of staff training on the knowledge of support staff in relation to bereavement and people with an intellectual disability [PDF]

, 2012
This study aimed to investigate whether a 1-day training course improved support staff knowledge about bereavement and grief in people with a learning disability. A questionnaire based, mixed design was used.
Bennett, Blackman, Bonell-Pascual, Bowey, Boyden, Carder, Cathcart, Cathcart, Cochrane, Crick, Cullen, Delorme, Department of Health, Dodd, Dodd, Elliott, Hansson, Harper, Hollins, Hollins, James, Luchterhand, MacHale, McEvoy, Murray, Niedomysl, Oswin, Palazon, Parkes, Read, Read, Read, Read, Reynolds, Schuchter, Service, Sheldon, Stoddart, Stroebe, Stroebe, Stylianos, Wass, Worden, Wright   +43 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Student and instructor perceptions of feedback in veterinary clinical education, part II qualitative analysis

Frontiers in Education
IntroductionFeedback is a critical component of clinical and professional skill development in veterinary medical education that is influenced by hierarchical, structural, and psychosocial factors.
Shane D. Lyon, Katherine Fogelberg, Ariana Hinckley-Boltax, Michelle C. Coleman, Jonathan H. Foreman, Jody S. Frost, Jennifer L. Hodgson, Regina Schoenfeld-Tacher   +7 more
doaj   +1 more source

Lernen am späteren Arbeitsplatz: eine Analyse studentischer Erwartungen an den Stationseinsatz im Fachbereich der Inneren Medizin

GMS Zeitschrift für Medizinische Ausbildung, 2014
[english] Background: Learning on the ward as a practice-oriented preparation for the future workplace plays a crucial role in the medical education of future physicians.
Köhl-Hackert, Nadja, Krautter, Markus, Andreesen, Sven, Hoffmann, Katja, Herzog, Wolfgang, Jünger, Jana, Nikendei, Christoph   +6 more
doaj   +1 more source

Surface Electromyography in Clinical Practice. A Perspective From a Developing Country

Frontiers in Neurology, 2020
Surface electromyography (sEMG) has long been used in research, health care, and other fields such as ergonomics and brain-machine interfaces. In health care, sEMG has been employed to diagnose as well as to treat musculoskeletal disorders, pelvic floor ...
Hachi Manzur-Valdivia, Joel Alvarez-Ruf, Joel Alvarez-Ruf   +2 more
doaj   +1 more source

Deliberate clinical inertia: Using meta-cognition to improve decision-making [PDF]

, 2018
Deliberate clinical inertia is the art of doing nothing as a positive response. To be able to apply this concept, individual clinicians need to specifically focus on their clinical decision-making.
Croskerry, Pat, Cullen, Louise, Egerton-Warburton, Diana, Fatovich, Daniel M., Glasziou, Paul, Keijzers, Gerben, Scott, Ian A.   +6 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

An exploratory study on the elements that might affect medical students' and residents' responsibility during clinical training.

Journal of Medical Ethics and History of Medicine, 2015
We are now more or less confronting a "challenge of responsibility" among both undergraduate and postgraduate medical students and some recent alumni from medical schools in Iran.
Omid Asemani, Mohammad Taghi Iman, Marzieh Moattari, Seyed Ziaadin Tabei, Farkhondeh Sharif, Mohammad Khayyer   +5 more
doaj