Results 21 to 30 of about 3,600,128 (335)

Clinical Trial Results: A Clinical Trial Bazaar! [PDF]

open access: yesThe Oncologist, 2014
The Oncologist's Clinical Trial Results section welcomes both positive and negative results in an effort to share information, speed discovery, and inform the field. Clinical Trial Results submissions have shown how succinctly the salient features of a submission can be presented, with more in-depth information to be found online.
Susan E. Bates, Antonio Tito Fojo
openaire   +3 more sources

Novel indicator for the spread of new coronavirus disease 2019 and its association with human mobility in Japan

open access: yesScientific Reports, 2023
The Japanese government adopted policies to control human mobility in 2020 to prevent the spread of severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19). The present study examined the impact of human mobility
Yuta Kawakami   +6 more
doaj   +1 more source

Perceived barriers to pediatrician and family practitioner participation in pediatric clinical trials: Findings from the Clinical Trials Transformation Initiative. [PDF]

open access: yes, 2018
Despite legislation to stimulate pediatric drug development through clinical trials, enrolling children in trials continues to be challenging. Non-investigator (those who have never served as a clinical trial investigator) providers are essential to ...
Benjamin, Daniel K   +12 more
core   +2 more sources

A randomized multicenter clinical trial to evaluate the efficacy of melatonin in the prophylaxis of SARS-CoV-2 infection in high-risk contacts (MeCOVID Trial): A structured summary of a study protocol for a randomised controlled trial

open access: yesTrials, 2020
Objectives Primary objective: to evaluate the efficacy of melatonin as a prophylactic treatment on prevention of symptomatic SARS-CoV-2 infection among healthcare workers at high risk of SARS-CoV-2 exposure. Secondary objectives: To evaluate the efficacy
Irene García García   +13 more
doaj   +1 more source

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]

open access: yes, 2012
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat   +31 more
core   +1 more source

Tanshinone ΙΙA-Incubated Mesenchymal Stem Cells Inhibit Lipopolysaccharide-Induced Inflammation of N9 Cells through TREM2 Signaling Pathway

open access: yesStem Cells International, 2022
Our previous study found that incubating mesenchymal stem cells (MSC) with tanshinone IIA (TIIA) before transplantation could significantly increase the inhibitory effect of MSC on neuroinflammation.
Nanqu Huang   +5 more
doaj   +1 more source

Safety and Tolerability of an Antimalarial Herbal Remedy in Healthy Volunteers: An Open-Label, Single-Arm, Dose-Escalation Study on Maytenus senegalensis in Tanzania

open access: yesTropical Medicine and Infectious Disease, 2022
Background: Though Maytenus senegalensis is one of the medicinal plants widely used in traditional medicine to treat infectious and inflammatory diseases in Africa, there is a lack of safety data regarding its use.
Kamaka Kassimu   +25 more
doaj   +1 more source

Decision aids can support cancer clinical trials decisions: Results of a randomized trial [PDF]

open access: yes, 2016
BACKGROUND. Cancer patients often do not make informed decisions regarding clinical trial participation. This study evaluated whether a web-based decision aid (DA) could support trial decisions compared with our cancer center’s website. METHODS.
Byrne, Margaret M   +5 more
core   +2 more sources

Research ethics consultation: an attempt and 5-year experience in a Japanese University Hospital

open access: yesBMC Research Notes, 2018
Objective Research ethics consultation is an advisory activity that differs from ethics committees, and its role is not yet widely known in Japan. Research ethics consultations were started in 2012 by members of the Clinical Trial Center of Tokushima ...
Hiroaki Yanagawa   +7 more
doaj   +1 more source

Disclosure of Clinical Trial Data: Why Exemption 4 of the Freedom of Information Act Should Be Restored [PDF]

open access: yes, 2005
Clinical trial data generated during the FDA drug approval process can be very valuable. While patients and doctors desperately need this information to make informed choices about medical treatment, drug sponsors strive to keep this resource secret to ...
Boyce, Janene
core   +2 more sources

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