Results 51 to 60 of about 1,889,174 (167)

Pharmacokinetics and Bioequivalence of Two Formulations of Azithromycin Tablets: A Randomized, Single-Dose, Three-Period, Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions

Drugs in R&D
Background and Objective Azithromycin is the first azalide antibiotic that is related to the macrolide family of antibiotics. Bioequivalence studies in China are initiated by the National Medical Products Administration (NMPA), which supports a generic ...
Yingrong Chen, Libing Ye, Jue Mei, Mengli Tian, Min Xu, Qiuyue Jin, Xiang Yu, Shuixin Yang, Jie Wang   +8 more
doaj   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous Administration JMKX003142 in Chinese Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Single, and Multiple Ascending Dose Phase I Clinical Trial

Drug Design, Development and Therapy
Cheng Cui,1– 3 Jixiang Zhu,1,2 Zhiping Liu,1– 3 Jingyao Liu,1,2 Xiaomin Huang,1,2 Yi Liu,4 Jingqiu Hu,4 Lingli Zhang,4 Xue Zhang,4 Yila Sha,4 Dongyang Liu,1– 3 Haiyan Li1– 3 1Drug Clinical Trial Center, Department of Pharmacy, Peking University Third ...
Cui C, Zhu J, Liu Z, Liu J, Huang X, Liu Y, Hu J, Zhang L, Zhang X, Sha Y, Liu D, Li H   +11 more
doaj  

Recent landscape and trends for industry‐sponsored pediatric clinical trials in China from 2013 to 2022

Pediatric Investigation
Importance Pediatric medication is a challenging issue globally. Promoting trials of medications for children and implementing measures to encourage innovation for addressing unmet medical and health needs are important.
Chang Liu, Yi Liu, Ling Ou, Yuenan Qi, Jianmin Zhang   +4 more
doaj   +1 more source

LEGAL ASPECTS OF CLINICAL TRIALS INVOLVING UNDER-AGE SUBJECTS IN RUSSIA

Педиатрическая фармакология, 2010
The article focuses on a complicated, no less pressing issue of conducting clinical trials in pediatrics. When vulnerable groups of patients are involved as subjects in clinical trials, specific ethical issues inevitably arise.
S.S. Zavidova, A.A. Tolpanova
doaj   +2 more sources

Regular human insulins versus rapid-acting insulin analogues in children and adolescents with type 1 diabetes: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis

Systematic Reviews
Background Type 1 diabetes is a serious, chronic disorder with an increasing incidence among children and adolescents. Glycemic control in individuals with type 1 diabetes is better managed through a basal-bolus regimen with either regular human or rapid-
Johanne Juul Petersen, Sophie Juul, Caroline Barkholt Kamp, Pascal Faltermeier, Christina Dam Bjerregaard Sillassen, Tiago Jeronimo Dos Santos, Janus Christian Jakobsen   +6 more
doaj   +1 more source

Paediatric Phase I/II Clinical Trial Assessments Under the New EU Clinical Trial Regulation: A Descriptive Analysis. [PDF]

Pharmaceut Med
Fankhauser L, Ligas F, Lesa G, Karlsen AS, Lunzer M, Al M, Scherer S, Benchetrit S, Riedel C, Kopp-Schneider A, Witt R, Witt O, Karres D, van Tilburg CM.   +13 more
europepmc   +1 more source

Clinical trial simulation of antiviral drugs. [PDF]

J Virol
Schiffer JT, Reeves DB, Mayer B, Rodriguez LR, Duke ER, Haddock B, Avila-Ponce de Leon U, Iwami S, Owens K, Esmaeili-Wellman S.   +9 more
europepmc   +1 more source

Clinical trials

, 2016
Phillips, Patrick PJ, Nunn, Andrew J
openaire   +2 more sources

The Prospective Registration of Clinical Trial Protocols: When Is a Health-Related Intervention Study Not a 'Clinical Trial'? [PDF]

Nurs Rep
Bressington D, Suriyawong W, Pipatpiboon N, Gray R.   +3 more
europepmc   +1 more source

Putting clinical trials on trial [PDF]

Nature Reviews Nephrology, 2009
openaire   +2 more sources