Results 71 to 80 of about 13,113,839 (405)

Neuroprotective Properties of Xenon. [PDF]

, 2020
Xenon is a rare noble gas that was introduced into clinical practice more than 70 years ago. Xenon's clinical properties are predicated by its ability to fit into preformed cavities of macromolecules thereby altering their biological functions.
Laitio, Timo, Maze, Mervyn
core  

A novel universal device "LINGUAL RING Ri.P.A.Ra" for TMDs and cranio-cervico-mandibular pains: preliminary results of a randomized control clinical trial [PDF]

, 2018
The aim of this study was to evaluate functionality and clinical application of a novel immediate device in the treatment of temporomandibular disorders (TMDs).
Di Paolo, C, Papi, P, Polimeni, A, Pompa, G, Rampello, A, Rampello, A   +5 more
core   +1 more source

Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.

Journal of the American Medical Association (JAMA), 2011
CONTEXT Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of early breast cancer, but it is not clear whether further nodal dissection affects survival.
A. Giuliano, K. Hunt, K. Ballman, P. Beitsch, P. Whitworth, P. Blumencranz, A. Leitch, S. Saha, L. Mccall, M. Morrow   +9 more
semanticscholar   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Persian medicine anti-dandruff topical remedies: a narrative review [PDF]

Journal of Medicinal Plants, 2022
Background: Dandruff is a common and important scalp disorder affecting almost half of the population at the pre-pubertal age. Various studies have shown that using herbs can be a good option for improving dandruff. There is a way to search for effective
Mohsen Naseri, Maryam Iranzadasl, Farzaneh Ghaffari, Vahedeh Naseri, Fatemeh Emadi, Fatemeh Alijaniha, Abdolazim Behfar, Zahra Bahaeddin   +7 more
doaj  

The Investigational Clinical Center: a clinical-supportive and patient-centered trial unit model. Ten years of experience through normal and pandemic times of a large pediatric trial center in Italy

Italian Journal of Pediatrics, 2021
Evidence-based medicine relies on appropriately designed, conducted and reported clinical trials (CTs) to provide the best proofs of efficacy and safety for pharmacological and non-pharmacological treatments.
Giuseppe Pontrelli, Marco Ciabattini, Franco De Crescenzo, Isabella Biondi, Rossana Cocchiola, Giorgia Copponi, Claudia Frillici, Francesca Molinari, Francesca Rocchi, Alessandra Simonetti, Paolo Rossi, Susanna Livadiotti   +11 more
doaj   +1 more source

Clinical trial site matching with improved diversity using fair policy learning [PDF]

arXiv, 2022
The ongoing pandemic has highlighted the importance of reliable and efficient clinical trials in healthcare. Trial sites, where the trials are conducted, are chosen mainly based on feasibility in terms of medical expertise and access to a large group of patients.
arxiv  

Feasibility of a randomized controlled trial of functional strength training for people between six months and five years after stroke: FeSTivaLS trial [PDF]

, 2014
Background: Functional Strength Training (FST) could enhance recovery late after stroke. The aim of this study was to evaluate the feasibility of a subsequent fully powered, randomized controlled trial.
Barton, Garry R., Clark, Allan, Cross, Jane, Mares, Kathryn, McGlashan, Kate, Myint, Phyo K., O'Ddriscoll, Marie-Luce, Poland, Fiona, Pomeroy, Valerie M., Vaughan, Susan, Watson, Martin   +10 more
core   +1 more source

A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.

New England Journal of Medicine, 1999
BACKGROUND To determine whether a restrictive strategy of red-cell transfusion and a liberal strategy produced equivalent results in critically ill patients, we compared the rates of death from all causes at 30 days and the severity of organ dysfunction.
Paul C. Hébert, G. Wells, M. Blajchman, John C. Marshall, C. Martin, G. Pagliarello, M. Tweeddale, I. Schweitzer, E. Yetisir   +8 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source