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What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]
São Paulo Medical Journal, 2023 BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco +2 more
doaj +1 more source
Clinical Trials in Portugal: How Can we Improve?
Acta Médica Portuguesa, 2021 N/a.
Marta Carvalho +9 more
doaj +1 more source
Reassessment of Historical Clinical Trials Supports the Effectiveness of Phage Therapy
Clinical Microbiology Reviews, 2022 Phage therapy has become a hot topic in medical research due to the increasing prevalence of antibiotic-resistant bacteria strains. In the treatment of bacterial infections, bacteriophages have several advantages over antibiotics, including strain ...
L. Marongiu +4 more
semanticscholar +1 more source
Acta Médica Portuguesa, 2021 Introduction: The aim of this study was to investigate the Portuguese authorship in publications resulting from trials initiated by the industry or investigators and run in Portugal.
Maria Pinheiro Andrade +6 more
doaj +1 more source
Minority Enrollment in Phase II and III Clinical Trials in Urologic Oncology
Journal of Clinical Oncology, 2022 PURPOSE Proportionate minority representation in clinical trials is an important step toward addressing health care inequities. Given the paucity of data on this topic in urologic oncology, we sought to quantify the enrollment of minority patients in ...
J. Owens-Walton +4 more
semanticscholar +1 more source
A summary of current NKG2D-based CAR clinical trials
Immunotherapy Advances, 2021 Summary Cancer immunotherapies have significantly improved patient survival and treatment options in recent years. Nonetheless, the success of immunotherapy is limited to certain cancer types and specific subgroups of patients, making the development of ...
Sophie Curio +2 more
semanticscholar +1 more source
The Bayesian Design of Adaptive Clinical Trials
International Journal of Environmental Research and Public Health, 2021 This paper presents a brief overview of the recent literature on adaptive design of clinical trials from a Bayesian perspective for statistically not so sophisticated readers. Adaptive designs are attracting a keen interest in several disciplines, from a
A. Giovagnoli
semanticscholar +1 more source
Clinical Orthopaedics and Related Research, 2021 Background A lack of racial and ethnic representation in clinical trials may limit the generalizability of the orthopaedic evidence base as it applies to patients in underrepresented minority populations and perpetuate existing disparities in use ...
T. Cwalina +4 more
semanticscholar +1 more source