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What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]

open access: yesSão Paulo Medical Journal, 2023
BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco   +2 more
doaj   +1 more source

Clinical Trials in Portugal: How Can we Improve?

open access: yesActa Médica Portuguesa, 2021
N/a.
Marta Carvalho   +9 more
doaj   +1 more source

Reassessment of Historical Clinical Trials Supports the Effectiveness of Phage Therapy

open access: yesClinical Microbiology Reviews, 2022
Phage therapy has become a hot topic in medical research due to the increasing prevalence of antibiotic-resistant bacteria strains. In the treatment of bacterial infections, bacteriophages have several advantages over antibiotics, including strain ...
L. Marongiu   +4 more
semanticscholar   +1 more source

Portuguese Authorship in Published Clinical Trials: Differences in Industry and Investigator Initiated Trials

open access: yesActa Médica Portuguesa, 2021
Introduction: The aim of this study was to investigate the Portuguese authorship in publications resulting from trials initiated by the industry or investigators and run in Portugal.
Maria Pinheiro Andrade   +6 more
doaj   +1 more source

Potential Applications of Artificial Intelligence in Clinical Trials for Alzheimer’s Disease

open access: yesLife, 2022
Clinical trials for Alzheimer’s disease (AD) face multiple challenges, such as the high screen failure rate and the even allocation of heterogeneous participants.
Youngho Seo, Hyemin Jang, Hyejoo Lee
semanticscholar   +1 more source

Minority Enrollment in Phase II and III Clinical Trials in Urologic Oncology

open access: yesJournal of Clinical Oncology, 2022
PURPOSE Proportionate minority representation in clinical trials is an important step toward addressing health care inequities. Given the paucity of data on this topic in urologic oncology, we sought to quantify the enrollment of minority patients in ...
J. Owens-Walton   +4 more
semanticscholar   +1 more source

Cannabis for Medical Use: Analysis of Recent Clinical Trials in View of Current Legislation

open access: yesFrontiers in Pharmacology, 2022
Cannabis has long been regarded as a recreational substance in the Western world. The recent marketing authorization of some medicinal products of industrial origin and the introduction onto the market of inflorescences for medical use mean that medical ...
F. Baratta   +3 more
semanticscholar   +1 more source

A summary of current NKG2D-based CAR clinical trials

open access: yesImmunotherapy Advances, 2021
Summary Cancer immunotherapies have significantly improved patient survival and treatment options in recent years. Nonetheless, the success of immunotherapy is limited to certain cancer types and specific subgroups of patients, making the development of ...
Sophie Curio   +2 more
semanticscholar   +1 more source

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