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Methodological and statistical topics in randomized controlled clinical trials [PDF]
Cláudia Caminha Escosteguy
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Randomized clinical trial of topical mupirocin versus oral erythromycin for impetigo [PDF]
The safety and efficacy of a new topical antiinfective agent, mupirocin, was compared with that of oral erythromycin ethylsuccinate in the treatment of impetigo in children. Sixty-two children aged 5 months to 13 years with impetigo were assigned to be treated with either mupirocin in three daily applications or erythromycin ethylsuccinate (40 mg/kg of
J Goldfarb+4 more
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Clinical trial of a potent non-halogenated topical steroid, Budesonide
In a double-blind, randomized multi-centre study, 116 patients with psoriasis have been treated for 1-3 weeks with budesonide ointment (Preferid, Draco/Tika; a subsidiary of AB ASTRA), a new non-halogenated topical steroid. In a series of 11 patients a 0.025% budesonide ointment was significantly superior to placebo. In a second series, of 54 patients,
G, Agrup+8 more
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One hundred three patients with acne vulgaris were randomly designated to receive either a topical formulation of erythromycin plus zinc or a topical solution of 1% clindamycin phosphate (Cleocin-T). The patients treated themselves twice daily and were examined at 3, 6, 9, and 12 weeks after the start of therapy.
Lawrence A. Schachner+2 more
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Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing
Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy. There were 26 patients in each group. Group A received topical diltiazem in the anal region three times a day. Group B
Ulises Rodríguez-Wong+2 more
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Are wash outs needed in clinical trials of topical agents? [PDF]
Laura F. Sandoval, Steven R. Feldman
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Clinical Trial of Fluclorolone Acetonide, a new Topical Steroid
R R, Harman+3 more
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Effect of Microneedle Pretreatment on Topical Anesthesia [PDF]
Jennifer Ornelas+4 more
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Clinical trials of topical agents: Easy application but difficult design
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