Results 111 to 120 of about 565,685 (338)
Position Paper on Road Map for RNA Virus Research in India
The Indian subcontinent with its population density, climatic conditions, means of subsistence, socioeconomic factors as well as travel and tourism presents a fertile ground for thriving of RNA viruses. Despite being pathogens of huge significance, there
Guruprasad R. Medigeshi+2 more
doaj +1 more source
One hundred three patients with acne vulgaris were randomly designated to receive either a topical formulation of erythromycin plus zinc or a topical solution of 1% clindamycin phosphate (Cleocin-T). The patients treated themselves twice daily and were examined at 3, 6, 9, and 12 weeks after the start of therapy.
Lawrence A. Schachner+2 more
openaire +3 more sources
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
Weilong Zhang,1,* Yinghua Lv,1,* Juan Yang,1 Yunhui Chen,2 Yingchun He,1 Jihan Huang1 1Center for Drug Clinical Research, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203 ...
Zhang W+5 more
doaj
Study designs: Part 5 – interventional studies (II)
In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention).
Rakesh Aggarwal, Priya Ranganathan
doaj +1 more source
Developing a topic-based repository of clinical trial individual patient data: experiences and lessons learned from a pilot project [PDF]
Nancy Medley+5 more
openalex +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Patient and public involvement in the design of clinical trials: An overview of systematic reviews [PDF]
BACKGROUNDFunders encourage lay-volunteer inclusion in research. There are controversy and resistance, given concerns of role confusion, exploratory methods, and limited evidence about what value lay-volunteers bring to research.
Albarqouni, Loai+6 more
core +3 more sources
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source