Results 21 to 30 of about 1,939,729 (406)

Minority Enrollment in Phase II and III Clinical Trials in Urologic Oncology

Journal of Clinical Oncology, 2022
PURPOSE Proportionate minority representation in clinical trials is an important step toward addressing health care inequities. Given the paucity of data on this topic in urologic oncology, we sought to quantify the enrollment of minority patients in ...
J. Owens-Walton, Cheyenne Williams, Alexis Rompré-Brodeur, Peter A. Pinto, M. Ball   +4 more
semanticscholar   +1 more source

A summary of current NKG2D-based CAR clinical trials

Immunotherapy Advances, 2021
Summary Cancer immunotherapies have significantly improved patient survival and treatment options in recent years. Nonetheless, the success of immunotherapy is limited to certain cancer types and specific subgroups of patients, making the development of ...
Sophie Curio, Gustav Jonsson, S. Marinović   +2 more
semanticscholar   +1 more source

The Bayesian Design of Adaptive Clinical Trials

International Journal of Environmental Research and Public Health, 2021
This paper presents a brief overview of the recent literature on adaptive design of clinical trials from a Bayesian perspective for statistically not so sophisticated readers. Adaptive designs are attracting a keen interest in several disciplines, from a
A. Giovagnoli
semanticscholar   +1 more source

Is Our Science Representative? A Systematic Review of Racial and Ethnic Diversity in Orthopaedic Clinical Trials from 2000 to 2020

Clinical Orthopaedics and Related Research, 2021
Background A lack of racial and ethnic representation in clinical trials may limit the generalizability of the orthopaedic evidence base as it applies to patients in underrepresented minority populations and perpetuate existing disparities in use ...
T. Cwalina, T. Jella, G. Manyak, Andy Kuo, A. Kamath   +4 more
semanticscholar   +1 more source

Molecular targets and gene therapy of lung cancer [PDF]

Archive of Oncology, 2009
Lung cancer is of great interest in human pathology because its apparent aggressiveness cannot be stopped by applied treatment procedures. The lack of highly specific screening tests prevents an early diagnosis of the disease.
Vasić Ljiljana
doaj   +1 more source

Can remote assistance for robotic surgery improve surgical performance in simulation training? A prospective clinical trial of urology residents using a simulator in south america

International Brazilian Journal of Urology, 2022
Introduction: We aimed to evaluate the role of remote proctoring during the initial training phases of a robotics curriculum using surgical robot skills simulator exercises.
Arie Carneiro, Oliver Rojas Claros, Jonathan Doyun Cha, Paulo Priante Kayano, Marcelo Apezzato, Andrew Aurel Wagner, Gustavo Caserta Lemos   +6 more
doaj   +1 more source

Profile of clinical research related to orthopedic disorders in the last five years

Journal of the Foot & Ankle, 2022
Objective: The aim of the study was to identify the profile of clinical research related to orthopedic disorders worldwide. Methods: A survey of clinical research in orthopedics was performed in the ClinicalTrials.gov platform and Plataforma Brasil ...
Luis Lopez Martinez, Caio de Oliveira Candido, Vinicius da Silva Naresse, Bruno Carraro Lolo, Silvonete Lima dos Santos, Alexandre Leme Godoy-Santos   +5 more
doaj   +1 more source

How can health economics be used in the design and analysis of adaptive clinical trials? A qualitative analysis [PDF]

, 2020
Introduction Adaptive designs offer a flexible approach, allowing changes to a trial based on examinations of the data as it progresses. Adaptive clinical trials are becoming a popular choice, as the prudent use of finite research budgets and accurate ...
Brennan, Alan, Flight, Laura, Hind, Daniel, Julious, Steven, Todd, Susan Todd   +4 more
core   +2 more sources

Impact of blinding on estimated treatment effects in randomised clinical trials: meta-epidemiological study

British medical journal, 2020
Objectives To study the impact of blinding on estimated treatment effects, and their variation between trials; differentiating between blinding of patients, healthcare providers, and observers; detection bias and performance bias; and types of outcome ...
Helene Moustgaard, G. Clayton, H. Jones, I. Boutron, Lars Jørgensen, D. L. T. Laursen, M. Olsen, A. Paludan-Müller, P. Ravaud, J. Savović, J. Sterne, J. Higgins, A. Hrõbjartsson   +12 more
semanticscholar   +1 more source

Paying clinicians to join clinical trials : a review of guidelines and interview study of trialists [PDF]

, 2009
Background: The motivations of clinicians to participate in clinical trials have been little studied. This project explored the potential role of payment for participation in publicly funded clinical trials in the UK.
Association of British Pharmaceutical Industries, British Medical Association, Christine Kerr, Clinical Research Report, D Fayter, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, General Medical Council, J Bryant, James Raftery, John Powell, ME Charlson, Medical Research Council, Nvivo, RJ Prescott, S Asch, S Hawker, Sheila Hawker, V Peto, WJ Jack   +23 more
core   +3 more sources