Results 21 to 30 of about 635,069 (409)

Impact of blinding on estimated treatment effects in randomised clinical trials: meta-epidemiological study

open access: yesBritish medical journal, 2020
Objectives To study the impact of blinding on estimated treatment effects, and their variation between trials; differentiating between blinding of patients, healthcare providers, and observers; detection bias and performance bias; and types of outcome ...
Helene Moustgaard   +12 more
semanticscholar   +1 more source

Occipital nerve stimulation for headache disorders [PDF]

open access: yes, 2010
Occipital nerve stimulation (ONS) was originally described in the treatment of occipital neuralgia. However, the spectrum of possible indications has expanded in recent years to include primary headache disorders, such as migraine and cluster headaches ...
Bartsch, Thorsten, Paemeleire, Koen
core   +2 more sources

Global trends in clinical trials involving pluripotent stem cells: a systematic multi-database analysis

open access: yesnpj Regenerative Medicine, 2020
Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to regenerate or replace functionally impaired tissues. Since the introduction of the induced pluripotent stem cell technology in 2006, the number of scientific ...
J. Deinsberger, D. Reisinger, B. Weber
semanticscholar   +1 more source

ASTRO Journals' Data Sharing Policy and Recommended Best Practices. [PDF]

open access: yes, 2019
Transparency, openness, and reproducibility are important characteristics in scientific publishing. Although many researchers embrace these characteristics, data sharing has yet to become common practice.
Braverman, Lisa   +8 more
core   +2 more sources

Applications of Blockchain Technology in Clinical Trials: Review and Open Challenges

open access: yesThe Arabian journal for science and engineering, 2020
Blockchain technology has disclosed unprecedented opportunities in the healthcare sector by unlocking the true value of interoperability. Specifically, the striking features of blockchain technology, such as data provenance, transparency, decentralized ...
Ilhaam A. Omar   +4 more
semanticscholar   +1 more source

The Effect of Sodium Hypochlorite and Chlorhexidine as Irrigant Solutions for Root Canal Disinfection: A Systematic Review of Clinical Trials [PDF]

open access: yes, 2016
Introduction This systematic review aimed to compare the effectiveness of sodium hypochlorite and chlorhexidine for root canal disinfection during root canal therapy.
Andrade Junior, C.V.   +4 more
core   +1 more source

A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)

open access: yesJournal of Applied Oral Science, 2010
INTRODUCTION: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which ...
Raphael Freitas de Souza   +3 more
doaj   +1 more source

Can real-world data really replace randomised clinical trials?

open access: yesBMC Medicine, 2020
Background Classically, randomised controlled trials (RCTs) are considered the gold standard for demonstrating product efficacy for the regulatory approval of medicines.
S. Ramagopalan, A. Simpson, C. Sammon
semanticscholar   +1 more source

SPOT: Sequential Predictive Modeling of Clinical Trial Outcome with Meta-Learning [PDF]

open access: yesACM International Conference on Bioinformatics, Computational Biology and Biomedicine, 2023
Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing trial outcome
Zifeng Wang, Cao Xiao, Jimeng Sun
semanticscholar   +1 more source

Trends and Features of the Applications of Natural Language Processing Techniques for Clinical Trials Text Analysis

open access: yesApplied Sciences, 2020
Natural language processing (NLP) is an effective tool for generating structured information from unstructured data, the one that is commonly found in clinical trial texts.
Xieling Chen   +5 more
semanticscholar   +1 more source

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