Results 21 to 30 of about 1,905,942 (404)
Objectives To study the impact of blinding on estimated treatment effects, and their variation between trials; differentiating between blinding of patients, healthcare providers, and observers; detection bias and performance bias; and types of outcome ...
Helene Moustgaard+12 more
semanticscholar +1 more source
Paying clinicians to join clinical trials : a review of guidelines and interview study of trialists [PDF]
Background: The motivations of clinicians to participate in clinical trials have been little studied. This project explored the potential role of payment for participation in publicly funded clinical trials in the UK.
Association of British Pharmaceutical Industries+23 more
core +3 more sources
What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients ...
Flavio D’Abramo+4 more
doaj +1 more source
Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to regenerate or replace functionally impaired tissues. Since the introduction of the induced pluripotent stem cell technology in 2006, the number of scientific ...
J. Deinsberger, D. Reisinger, B. Weber
semanticscholar +1 more source
Analyzing differences in the costs of treatment across centers within economic evaluations [PDF]
Objectives: Assessments of health technologies increasingly include economic evaluations conducted alongside clinical trials. One particular concern with economic evaluations conducted alongside clinical trials is the generalizability of results from one
Coyle, D, Drummond, M F
core +1 more source
Applications of Blockchain Technology in Clinical Trials: Review and Open Challenges
Blockchain technology has disclosed unprecedented opportunities in the healthcare sector by unlocking the true value of interoperability. Specifically, the striking features of blockchain technology, such as data provenance, transparency, decentralized ...
Ilhaam A. Omar+4 more
semanticscholar +1 more source
A Clinical Trial Design for Evaluating Topical Antimicrobials in Chronic Wounds: The BLEU Trial
Chronic wound management is a global challenge. Millions of patients suffer from nonhealing ulcers and health systems are overwhelmed by the growing demand for treatment. Despite the prevalence of chronic wounds, the emergence of wound centers and specialized physicians is a recent phenomenon.
Thomas Serena+3 more
openaire +3 more sources
ASTRO Journals' Data Sharing Policy and Recommended Best Practices. [PDF]
Transparency, openness, and reproducibility are important characteristics in scientific publishing. Although many researchers embrace these characteristics, data sharing has yet to become common practice.
Braverman, Lisa+8 more
core +2 more sources
Can real-world data really replace randomised clinical trials?
Background Classically, randomised controlled trials (RCTs) are considered the gold standard for demonstrating product efficacy for the regulatory approval of medicines.
S. Ramagopalan, A. Simpson, C. Sammon
semanticscholar +1 more source
Occipital nerve stimulation for headache disorders [PDF]
Occipital nerve stimulation (ONS) was originally described in the treatment of occipital neuralgia. However, the spectrum of possible indications has expanded in recent years to include primary headache disorders, such as migraine and cluster headaches ...
Bartsch, Thorsten, Paemeleire, Koen
core +2 more sources