Results 71 to 80 of about 608,159 (405)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Anticoagulants for acute ischaemic stroke [PDF]

open access: yes, 2015
Peer reviewedPublisher ...
Counsell, Carl   +2 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Optimal search strategies for identifying sound clinical prediction studies in EMBASE [PDF]

open access: yes, 2005
BACKGROUND: Clinical prediction guides assist clinicians by pointing to specific elements of the patient's clinical presentation that should be considered when forming a diagnosis, prognosis or judgment regarding treatment outcome.
A Laupacis   +25 more
core   +3 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Evaluation of sodium nitroprusside for controlled hypotension in children during surgery

open access: yesFrontiers in Pharmacology, 2015
Purpose. (1) To define the onset and offset of the blood-pressure-lowering effects of sodium nitroprusside (SNP) for use in developing instructions for dose titration in children undergoing a surgical or medical procedure, and (2) to assess the safety of
David R Drover   +7 more
doaj   +1 more source

Randomized clinical trial of topical tranexamic acid after reduction mammoplasty [PDF]

open access: yesBritish Journal of Surgery, 2015
Abstract Background The antifibrinolytic drug tranexamic acid is currently being rediscovered for both trauma and major surgery. Intravenous administration reduces the need for blood transfusion and blood loss by about one-third, but routine administration in surgery is not yet advocated owing to ...
Ausen, Kjersti   +3 more
openaire   +4 more sources

Calcific uraemic arteriolopathy - A mini-review [PDF]

open access: yes, 2016
Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica   +7 more
core  

A shared latent space matrix factorisation method for recommending new trial evidence for systematic review updates

open access: yes, 2018
Clinical trial registries can be used to monitor the production of trial evidence and signal when systematic reviews become out of date. However, this use has been limited to date due to the extensive manual review required to search for and screen ...
Bashir, Rabia   +5 more
core   +1 more source

“It’s trying to manage the work” : A qualitative evaluation of recruitment processes within a UK multi-centre trial [PDF]

open access: yes, 2017
Acknowledgments The authors would like to thank all interviewees who agreed to take part in this study. The authors would like to thank the TISU Trial Group for their support with this project. In particular, the authors would like to thank Sarah Cameron
Gillies, Katie   +2 more
core   +1 more source

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