Results 71 to 80 of about 612,154 (364)

Which Obstacles Prevent Us from Recruiting into Clinical Trials: A Survey about the Environment for Clinical Studies at a German University Hospital in a Comprehensive Cancer Center

Frontiers in Oncology, 2017
BackgroundProspective clinical studies are the most important tool in modern medicine. The standard in good clinical practice in clinical trials has constantly improved leading to more sophisticated protocols.
Christoph Straube, Christoph Straube, Christoph Straube, Peter Herschbach, Peter Herschbach, Peter Herschbach, Stephanie E. Combs, Stephanie E. Combs, Stephanie E. Combs, Stephanie E. Combs   +9 more
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Can implant surfaces affect implant stability during osseointegration? A randomized clinical trial

Brazilian Oral Research, 2018
This randomized clinical trial evaluated the insertion torque (IT), primary, and secondary stability of dental implants with different surface treatments during the osseointegration period.
Luiz Carlos do CARMO FILHO, Raissa Micaella MARCELLO-MACHADO, Eduardo Dickie de CASTILHOS, Altair Antoninha DEL BEL CURY, Fernanda FAOT   +4 more
doaj   +1 more source

Developing a complex intervention to improve prescribing safety in primary care:mixed methods feasibility and optimisation pilot study [PDF]

, 2014
Objectives (A) To measure the extent to which different candidate outcome measures identified high-risk prescribing that is potentially changeable by the data-driven quality improvement in primary care (DQIP) intervention.(B) To explore the value of ...
Dreischulte, Tobias, Grant, Aileen M., Guthrie, Bruce   +2 more
core   +7 more sources

Lavender-thymol as a new topical aromatherapy preparation for episiotomy: A randomised clinical trial.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016
The objective of this study was to evaluate the effectiveness of topical lavender-thymol in promoting episiotomy healing. This placebo-controlled, single-blinded, randomised clinical trial involved 60 primiparous women. REEDA score was used to evaluate the outcome of the trial.
T, Marzouk, R, Barakat, A, Ragab, F, Badria, A, Badawy   +4 more
openaire   +1 more source

Topical Tazarotene Gel, 0.1%, as a Novel Treatment Approach for Atrophic Postacne Scars

JAMA Facial Plastic Surgery, 2019
Evidence is robust for the effectiveness of microneedle therapy in the management of postacne atrophic scarring. A home-based topical treatment with an efficacy comparable to microneedling would be a useful addition in the armamentarium of acne scar management.To compare the efficacy of topical tazarotene gel, 0.1%, with microneedling therapy in the ...
T P, Afra, Muhammed, Razmi T, Tarun, Narang, Sunil, Dogra, Ashok, Kumar   +4 more
openaire   +3 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Hemorrhagic transformation: A review of the rate of hemorrhage in the major clinical trials of acute ischemic stroke

Frontiers in Neurology, 2013
Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic transformation. While significant advances have been made over the past two decades with regard to emergent treatment of AIS, many of these therapeutic options are ...
Eric S Sussman, Edward Sander Connolly Jr.   +1 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Mapping the evolving definitions of translational research

Journal of Clinical and Translational Science, 2017
Objective Systematic review and analysis of definitions of translational research. Materials and methods The final corpus was comprised of 33 papers, each
Daniel G. Fort, Timothy M. Herr, Pamela L. Shaw, Karen E. Gutzman, Justin B. Starren   +4 more
doaj   +1 more source