Results 71 to 80 of about 1,939,729 (406)

Clinical stakeholders' opinions on the use of selective decontamination of the digestive tract in critically ill patients in intensive care units : an international Delphi study [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Bellingan, Geoff   +11 more
core   +4 more sources

Trustworthiness of Patient-Reported Outcomes in Unblinded Cancer Clinical Trials.

open access: yesJAMA Oncology, 2017
There is substantial and growing interest in measuring patient-reported outcomes in drug development trials, 1 for example, to understand the effects of treatment on tumor-associated pain.
T. Atkinson, J. Wagner, E. Basch
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Hemorrhagic transformation: A review of the rate of hemorrhage in the major clinical trials of acute ischemic stroke

open access: yesFrontiers in Neurology, 2013
Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic transformation. While significant advances have been made over the past two decades with regard to emergent treatment of AIS, many of these therapeutic options are ...
Eric S Sussman   +1 more
doaj   +1 more source

Inadequate reporting quality of registered genome editing trials: an observational study

open access: yesBMC Medical Research Methodology, 2022
Background To assess registration completeness and safety data of trials on human genome editing (HGE) reported in primary registries and published in journals, as HGE has safety and ethical problems, including the risk of undesirable and unpredictable ...
Diana Jurić   +2 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Randomized clinical trial of topical tranexamic acid after reduction mammoplasty [PDF]

open access: yesBritish Journal of Surgery, 2015
Abstract Background The antifibrinolytic drug tranexamic acid is currently being rediscovered for both trauma and major surgery. Intravenous administration reduces the need for blood transfusion and blood loss by about one-third, but routine administration in surgery is not yet advocated owing to ...
Ausen, Kjersti   +3 more
openaire   +4 more sources

Choosing and using methodological search filters : searchers' views [PDF]

open access: yes, 2015
© 2014 The authors.
Beale, Sophie   +10 more
core   +1 more source

Can implant surfaces affect implant stability during osseointegration? A randomized clinical trial

open access: yesBrazilian Oral Research, 2018
This randomized clinical trial evaluated the insertion torque (IT), primary, and secondary stability of dental implants with different surface treatments during the osseointegration period.
Luiz Carlos do CARMO FILHO   +4 more
doaj   +1 more source

ITTC @ TREC 2021 Clinical Trials Track [PDF]

open access: yesarXiv, 2022
This paper describes the submissions of the Natural Language Processing (NLP) team from the Australian Research Council Industrial Transformation Training Centre (ITTC) for Cognitive Computing in Medical Technologies to the TREC 2021 Clinical Trials Track.
arxiv  

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