Results 71 to 80 of about 635,069 (409)

Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials

open access: yesBMC Medical Research Methodology, 2012
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design,
Hamm Michele P   +4 more
doaj   +1 more source

Inadequate reporting quality of registered genome editing trials: an observational study

open access: yesBMC Medical Research Methodology, 2022
Background To assess registration completeness and safety data of trials on human genome editing (HGE) reported in primary registries and published in journals, as HGE has safety and ethical problems, including the risk of undesirable and unpredictable ...
Diana Jurić   +2 more
doaj   +1 more source

Clinical Trials Corner

open access: yesNutrition and Healthy Aging, 2017
Welcome to the fi rst edition of the Clinical Trials Corner of Nutrition and Healthy Aging. The aim of this section is to inform readers of upcoming clinical trials and highlight new fi ndings. If you would like to draw attention to a specifi c topic and
L. Heilbronn
semanticscholar   +1 more source

Clinical Assessment of Topical Methotrexate Micro-emulsion as a Treatment for Psoriasis: A Randomized Clinical Trial

open access: yesHormozgan Medical Journal
Objectives: Psoriasis is an inflammatory skin disease, and the main topical treatment for this disease is corticosteroids, vitamin D analogs, salicylic acid, and calcineurin inhibitors. This study clinically evaluates a topical dosage form of methotrexate (MTX) micro-emulsion and compares it with clobetasol lotion.
Mohammad Sadegh Sayyafan   +4 more
openaire   +1 more source

A shared latent space matrix factorisation method for recommending new trial evidence for systematic review updates

open access: yes, 2018
Clinical trial registries can be used to monitor the production of trial evidence and signal when systematic reviews become out of date. However, this use has been limited to date due to the extensive manual review required to search for and screen ...
Bashir, Rabia   +5 more
core   +1 more source

A Practical Application Primer on Cognitive Behavioral Therapy for Insomnia for Medical Residents [PDF]

open access: yes, 2019
Introduction: Cognitive behavioral therapy for insomnia (CBT-I) is a well-established nonpharmacological intervention that is the gold standard treatment for insomnia.
Chernyak, Yelena
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

Which Obstacles Prevent Us from Recruiting into Clinical Trials: A Survey about the Environment for Clinical Studies at a German University Hospital in a Comprehensive Cancer Center

open access: yesFrontiers in Oncology, 2017
BackgroundProspective clinical studies are the most important tool in modern medicine. The standard in good clinical practice in clinical trials has constantly improved leading to more sophisticated protocols.
Christoph Straube   +9 more
doaj   +1 more source

Social media and clinical trials: The pros and cons gain context when the patient is at the center

open access: yesCancer, 2018
Less than 10% of patients in the United States enroll in clinical trials, and even lower rates are noted among minority populations. Barriers to recruitment include lack of awareness, strictness of eligibility, and practical concerns, including travel ...
M. Thompson, R. O'Regan
semanticscholar   +1 more source

Calcific uraemic arteriolopathy - A mini-review [PDF]

open access: yes, 2016
Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica   +7 more
core  

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