Results 51 to 60 of about 4,021 (200)

Strengths and Limitations of Sodium Lauryl Sulfate as an Irritant Control in Patch Testing

Contact Dermatitis, Volume 94, Issue 4, Page 338-346, April 2026.
Positive SLS reactions occurred in 22% of 43 478 patients and correlated predominantly with irritant‐prone allergens. Thirty‐one of 189 allergen preparations showed significant associations, strongest for cocamidopropyl betaine, formaldehyde, sorbic acid and DPG. A simple positive/negative SLS classification was diagnostically sufficient.
Susann Forkel, Silke S. Matzke, Moritz M. Hollstein, Burkhard Kreft, Harald Löffler, Christoph Skudlik, Mathias Sulk, Guido Heine, Andrea Bauer, Nicola Wagner, Annice Heratizadeh, Timo Buhl   +11 more
wiley   +1 more source

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

Cell Proliferation, Volume 59, Issue 3, March 2026.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie, Yu Wang, Wenjie Cheng, Minbo Yan, Kunyu Li, Xiang Wu, Jiaqing Wu, Zhuangzhuang Zhang, Yingbo Dai   +8 more
wiley   +1 more source

Clioquinol derivatives as potent inhibitors of Methicillin-Resistant Staphylococcus aureus and their mechanistic study

Results in Chemistry
Aims: Methicillin-Resistant Staphylococcus aureus cause many nosocomial, and community-acquired infections, burdening healthcare systems globally. The aim of the current study was to identify the potent inhibitors of MRSA strains as first step towards ...
Sumaira Hamid, Atia-tul-Wahab, Shoukat Wali, Humaira Zafar, M. Iqbal Choudhary   +4 more
doaj   +1 more source

Isolation and Characterisation of Serotype III in Miamiensis avidus (Ciliophora: Scuticociliatida) From Olive Flounder (Paralichthys olivaceus)

Journal of Fish Diseases, Volume 49, Issue 2, February 2026.
ABSTRACT Miamiensis avidus (Ciliophora: Scuticociliatida, syn. Philasterides dicentrarchi) is a significant pathogen causing scuticociliatosis in olive flounder (Paralichthys olivaceus) in Korea and Japan. In this study, the BB19 strain, isolated from olive flounder, was identified as M.
Jin‐Young Kim, Jeong‐Hoon Kim, Su‐Mi Shin, Taeho Kim, Se Ryun Kwon, Sung‐Ju Jung   +5 more
wiley   +1 more source

Policy formation and debate concerning the government regulation of ayurveda in Great Britain in the twenty-first century [PDF]

, 2005
Since 2000, the British House of Lords and the Government have been working towards a regulatory scheme for Complementary and Alternative medicine in Britain, a scheme that will include ayurveda.The present paper discusses these regulatory moves by the ...
Wujastyk, D
core  

Smart systems related to polypeptide sequences [PDF]

, 2016
Increasing interest for the application of polypeptide-based smart systems in the biomedical field has developed due to the advantages given by the peptidic sequence.
Franco García, María Lourdes, Puiggalí Bellalta, Jordi, Valle Mendoza, Luis Javier del   +2 more
core   +2 more sources

Pre-Clinical Pharmacokinetics, Tissue Distribution and Physicochemical Studies of CLBQ14, a Novel Methionine Aminopeptidase Inhibitor for the Treatment of Infectious Diseases

Drug Design, Development and Therapy, 2020
Oscar Ekpenyong, Xiuqing Gao, Jing Ma, Candace Cooper, Linh Nguyen, Omonike A Olaleye, Dong Liang, Huan Xie Department of Pharmaceutical and Environmental Health Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX ...
Ekpenyong O, Gao X, Ma J, Cooper C, Nguyen L, Olaleye OA, Liang D, Xie H   +7 more
doaj  

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

Neurobiology of Disease, 2015
Iron accumulation and tau protein deposition are pathological features of Alzheimer's (AD) and Parkinson's diseases (PD). Soluble tau protein is lower in affected regions of these diseases, and we previously reported that tau knockout mice display motor ...
Peng Lei, Scott Ayton, Ambili Thoppuvalappil Appukuttan, Irene Volitakis, Paul A. Adlard, David I. Finkelstein, Ashley I. Bush   +6 more
doaj   +1 more source

Diclofenac impairs autophagic flux via oxidative stress and lysosomal dysfunction: Implications for hepatotoxicity

Redox Biology, 2020
Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with various side effects, including cardiovascular and hepatic disorders. Studies suggest that mitochondrial damage and oxidative stress are important mediators of toxicity, yet ...
Seung-Hwan Jung, Wonseok Lee, Seung-Hyun Park, Kang-Yo Lee, You-Jin Choi, Soohee Choi, Dongmin Kang, Sinri Kim, Tong-Shin Chang, Soon-Sun Hong, Byung-Hoon Lee   +10 more
doaj   +1 more source

Clioquinol inhibits zinc-triggered caspase activation in the hippocampal CA1 region of a global ischemic gerbil model. [PDF]

PLoS ONE, 2010
BACKGROUND: Excessive release of chelatable zinc from excitatory synaptic vesicles is involved in the pathogenesis of selective neuronal cell death following transient forebrain ischemia.
Tao Wang, Wei Zheng, He Xu, Jia-Min Zhou, Zhan-You Wang   +4 more
doaj   +1 more source