Results 101 to 110 of about 363,591 (305)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

System for generating timing and control signals [PDF]

open access: yes, 1975
A system capable of generating every possible data frame subperiod and delayed subperiod of a data frame of length of M clock pulse intervals (CPIs) comprised of parallel modulo-m sub i counters is presented.
Messner, A., Perlman, M., Rousey, W. J.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Possible Role of Extra-ocular Photoreceptors in the Entrainment of Lobster Circadian Rhythms to Light:Dark Cycles [PDF]

open access: yes, 2013
The American lobster, Homarus americanus, is a decapod crustacean whose daily nocturnal rhythms of activity are driven, in part, by an internal biological clock. While this circadian clock is capable of producing a rhythm of approximately 24 hours on its
McKinney, Sara A
core   +1 more source

Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]

open access: yes, 2015
Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Missed medical appointments during shifts to and from daylight saving time [PDF]

open access: yes, 2017
Transitions into and out of Daylight Saving Time (DST) can provide insights into how a minor change to a regular sleep–wake cycle can inadvertently affect health. We examined the relationship between DST and missed medical appointments.
Altman DG.   +3 more
core   +2 more sources

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