Results 121 to 130 of about 363,591 (305)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A solar cycle clock for extreme space weather
Scientific ReportsAbstract The variable solar cycle of activity is a long-standing problem in physics. It modulates the overall level of space weather activity at earth, which in turn can have significant societal impact. The Hilbert transform of the sunspot number is used to map the variable length, approximately 11 year Schwabe cycle onto a uniform clock.
Chapman, S. C., Dudok de Wit, Thierry
openaire +6 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Internal Clock Drift Estimation in Computer Clusters
Journal of Computer Systems, Networks, and Communications, 2008 Most computers have several high-resolution timing sources, from the programmable interrupt timer to the cycle counter. Yet, even at a precision of one cycle in ten millions, clocks may drift significantly in a single second at a clock frequency of ...
Hicham Marouani, Michel R. Dagenais
doaj +1 more source
An improved instruction-level power model for ARM11 microprocessor
, 2014 The power and energy consumed by a chip has become the primary design constraint for embedded systems, which has led to a lot of work in hardware design techniques such as clock gating and power gating.
Wang, Wei, Zwolinski, Mark
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Research progress of biological clock in regulation of tumor development [PDF]
Jichu yixue yu linchuang, 2020 Biological clock is a physiological controlling system with self-regulating functions. There is a close relationship between biological clock disorders and the occurrence of tumors, but underlying mechanism has not yet been elucidated.
GAO Dong-xiao, LIU Dan, GUO Qiang, LUO Ying, LIU Jing
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The Ifo Business Cycle Clock: Circular Correlation with the Real GDP [PDF]
The Ifo Business Climate is the most important indicator for the business cycle in Germany. In 1993 the connection between the two components of the business climate – business situation and business expectations – was graphically portrayed by Ifo in a 4-
Klaus Abberger, Wolfgang Nierhaus
core
Architecture Design Space Exploration for Streaming Applications Through Timing Analysis [PDF]
, 2005 In this paper we compare the maximum achievable throughput of different memory organisations of the processing elements that constitute a multiprocessor system on chip.
Jansen, Pierre G. +3 more
core +4 more sources